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Assunta Krehl

Pharmafocus.com - 0 views

  • Canada has always had to fight hard to attract talent and investment
  • MaRS Vital to Toronto's life sciences vision is MaRS (derived from Medical and Related Sciences) a non-profit organisation and business centre located in the heart of the city. Its core function is as a biotech incubator and business park, known as MaRS Discovery District. The venture was first established in 2000 to help foster and accelerate the growth of successful Canadian businesses and, after some uncertain times, it is now gathering momentum. A separate technology transfer office, MaRS Innovation, has also been established that, it is hoped, can be a world beater in its own right (see Turning good ideas into world beaters below). The location of the MaRS building in central Toronto is important, as it is just a stone's throw away from an existing cluster of universities and academic hospitals. MaRS has many links with other research-based organisations, including collaborations with three local universities, 10 academic teaching hospitals and the Ontario Institute for Cancer Research. MaRS occupies the Old Toronto general hospital, where insulin was first discovered by Best and Banting in 1921 and then developed for use in human trials. The 21st Century organisation can build on this heritage in patient-focused discovery and development. Formerly the head of venture capital firm Primaxis, Ilse Treurnicht is chief executive of MaRS Discovery District. She acknowledges the crisis in venture capital funding, and says Canada's sector has always had less access funds through this route than other countries. This is one of the drivers behind the search for a new approach. Treurnicht says the old models of building biotech and life sciences businesses have to be discarded, as they have failed to build companies with critical mass. She says MaRS' new 'Convergence Innovation' strategy of bringing science, capital and business together will pay off.
  • "We call our strategy 'Convergence Innovation' and what we are trying to do is move away from the old linear model of academics struggling in their spare time to build companies or entrepreneurs doing this in a very incremental way."It takes time and it has many risk points along the way. So using this Convergence centre model to create a much more dynamic organisation which can help accelerate good ideas towards the commercialisation." But she says Canada's geography and demographics are always going to be a challenge. "This is a very large country with a small population. If you think in terms of clusters and hub regions, Canada's business hubs are separated geographically, and there is not much in between in terms of people."That means we can't try to be a little United States, because we just won't show up on the radar. We have to take a different approach. We have to think about collaboration as our potential competitive advantage - that means using networks and associations to solve problems and build businesses."So as new opportunities emerge, we can take them to market faster and hopefully with a higher success rate." The centre currently accommodates numerous start up companies, as well as those providing legal and financial services to them. AstraZeneca and GlaxoSmithKline also have offices on site. In all, MaRS provides mentoring for over 200 different companies across Ontario, and runs courses on entrepreneurship and preparing products for market.
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  • Transition Therapeutics is one of the companies based at MaRS, and is an example of a biopharmaceutical company that is taking a new approach to the science and business of drug development.
  • Now Toronto's MaRS Innovation (MI) has been launched to try to guide and accelerate these promising ideas out of the wilderness and onto the market. MI is a not-for-profit technology transfer company that will channel all the best ideas to come out of Toronto's renowned academic centres. In the Toronto and Ontario area there were between 14-16 different technology transfer offices in the different institutions, and MaRS Innovation resolved to bring these interests together into a single entity after industry partners told them it was an inefficient way to do business. Bringing together the different institutions under one umbrella organisation has been an arduous task for MaRS, but the reward could be considerable for all parties. MI now oversees probably the largest intellectual property pipeline of its kind, representing about $1 billion in annual research spending. This means MI will be a unified route for all of Toronto's academics and their institutions when they want to develop and commercialise a bright idea. Most importantly, investors from industry who are looking to collaborate will now be able to deal with just organisation and one IP process. MI will cover patentable ideas across a broad range of areas, and not just life sciences - the discovery pipeline in physical sciences, information and communication technology, and green technology ('cleantech') will all be funnelled through MI. MI now represents three universities, 10 academic teaching hospitals and the Ontario Institute for Cancer Research. MaRS Innovation, with support from MaRS and BioDiscovery Toronto, will advance commercialisation through industry partnerships, licensing and company creation.
  • ts chief executive is Dr Rafi Hofstein. Hofstein has been headhunted from Israel where he was chief executive of Hadasit, the technology transfer company of the Hadassah Medical Organization in Jerusalem and chair of the publicly-traded company Hadasit BioHolding. He brings this considerable experience in technology transfer to what he thinks is a groundbreaking enterprise."MaRS Innovation is a unique global initiative, and I must commend the institutional leaders in Toronto for pulling this innovation powerhouse together to strengthen commercialisation output." He adds: "I believe this is going to modernise the whole notion of tech transfer." He says the scale and diversity of MaRS Innovation's remit puts it into a league of its own. Other research clusters elsewhere in the world have attempted similar projects before, but have been thwarted by the difficulty in bringing parties together. MaRS Innovation will also help launch and grow new spin-off companies and incubate them for 2-3 years to ensure a strong commercial footing. Hofstein says MI will also fund proof of concept trials which will persuade major pharma companies to invest in their development.
  • MI has just announced its first two commercialisation deals with academic partners in the city. The first is with the Samuel Lunenfeld Research Institute of Mount Sinai Hospital to develop stem cell from umbilical cords to treat cardiovascular disease, diabetes and neurological disorders. "With the Toronto area identified as a world-leading cluster in stem cell research, we are extremely excited to have identified this technology as our first commercialisation opportunity," said Dr Hofstein.
  • "Our partnership with MaRS Innovation on developing methods for using stem cells for diseases such as diabetes will allow us to work towards advancing care for these critical conditions."
  • The second collaboration is between MI and The University of Toronto (U of T) and involves a novel sustained release formulation of nitric oxide (NO) for applications in wound healing, including diabetic ulcers. "There are 300 million diabetics worldwide, of which some 15% develop troublesome foot ulcers. This wound healing technology is extremely exciting, making it an early commercialisation opportunity that MaRS Innovation has identified as being a potential win for some 45 million diabetics globally," said Dr Hofstein.
  • "This is one of many new commercialisation ventures that will be initiated by MaRS Innovation, our partner in commercialisation of research with 13 other academic institutions across the Greater Toronto Area," said Paul Young, U of T's vice-president, Research. "We at U of T are delighted that this innovation from Dr Lee will be taken to the marketplace to the benefit of society and the economy of Ontario and Canada." By aggregating the leading edge science of its institutional members and being a one-stop commercialisation centre for industry, entrepreneurs and investors, MI could really help put Toronto and Canada on the map."MaRS Innovation is deeply committed to facilitating strategic research collaborations with industry partners, strengthening the innovation capacity of Canadian industry through adoption of new technologies, and launching a new generation of robust, high-growth Canadian companies that will become global market leaders," added Dr Hofstein. "We look forward to working closely with all of our institutional members and to continue to jointly announce exciting commercial opportunities."
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    Canada has always had to fight hard to attract talent and investment. As stated in Pharmafocus.com, "MaRS Discovery District helps to foster and accelerate the growth of successful Canadian businesses." MaRS Innovation has also been launched to accelerate ideas onto the market.
Assunta Krehl

"mesh09 kicks off!" - Social Media Release - 0 views

  • April 6, 7 & 8 at the MaRS Centre in Toronto, mesh is the place to be for exciting discussions about the ever-changing online world.
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    Mention of mesh09 kick off April 6 -8 at the MaRS Centre.
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    Mention of mesh09 kick off April 6 -8 at the MaRS Centre. April 6, 2009
Assunta Krehl

YFile - How to prevent wrongful convictions caused by misuse of science - 0 views

  • It will take place on Saturday from 9am to 5pm at the MaRS Centre, 101 College Street at University Avenue.
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    Expert Forensic Evidence in Criminal Proceedings: Avoiding Wrongful Convictions, is jointly organized by Osgoode Professional Development (the professional development program of York's Osgoode Hall Law School) and the Centre for Forensic Science & Medicine at the University of Toronto. Mention that the conference will be held at the MaRS Centre.
Assunta Krehl

Canadian Consulting Engineer - Ontario aims to become centre of water expertise - May 3... - 0 views

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    The Ontario Society of Professional Engineers held its second symposium related to climate change on April 29 in Toront,.Entitled, "Engineering in a Climate of Change: Making the Lakes Great." This event was held at the MaRS Centre, in cooperation with the ArcelorMittal Dofasco Centre for Engineering and Public Policy at McMaster University.
Assunta Krehl

MaRS Awarded $1.3 Million By Rockefeller Foundation and J.W. McConnell Family Foundatio... - 1 views

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    MaRS Discovery District announced  substantial funding support from the Rockefeller Foundation and the J.W. McConnell Family Foundation will be made available for the Centre for Impact Investing, to be housed at MaRS.
Assunta Krehl

MaRS to launch Centre for Impact Investing - The Globe and Mail - September 28, 2011 - 0 views

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    MaRS Discovery District announced  substantial funding support from the Rockefeller Foundation and the J.W. McConnell Family Foundation will be made available for the Centre for Impact Investing, to be housed at MaRS.
Assunta Krehl

MaRS Awarded $1.3 Million By Rockefeller Foundation and J.W. McConnell Family Foundatio... - 0 views

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    MaRS Discovery District announced   substantial funding support from the Rockefeller Foundation and the J.W. McConnell Family Foundation will be made available for the Centre for Impact Investing, to be housed at MaRS.
Assunta Krehl

The Centre for Commercialization of Regenerative Medicine (CCRM): CCRM Announces Its In... - 0 views

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    Rafi Hofstein, President and CEO of MaRS Innovation is one of the inaugural Board of Directors for The Centre for Commercialization of Regenerative Medicine (CCRM). CCRM is a MaRS tenant.
Assunta Krehl

Grand Opening of the Stephen Hawking Centre at Ontario, Canada-based Perimeter Institut... - 0 views

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    The Stephen Hawking Centre is now open at the Perimeter Institute for Theoretical Physics (PI) in Ontario, Canada.The Phase II of the MaRS Discovery District construction is just one in a series of recent, major investments that are increasing Ontario's innovation, research and development capacities.
Assunta Krehl

Goar: Micro-loans unlock trap of mental illness - Toronto Star - January 10, 2012 - 0 views

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    People with mental health challenges can run viable businesses. Rotman School of Management at the University of Toronto and the Centre for Addiction and Mental Health (CAMH) did an experiment with to see if microcredit could make a difference and it did. Rise Asset Development was created.The MaRS centre, which incubates innovative businesses, is providin support.
Assunta Krehl

U of Windsor research could halt advance of Parkinson's - Vancouver Sun - 0 views

  • Michael J. Fox addresses the media and introduces his Parkinson's disease foundation at the MaRS Centre in Toronto Ont. on September 24, 2009. Each time University of Windsor graduate student Katie Facecchia sees actor Michael J. Fox on television, talking about his life-and-death battle with Parkinson's disease, she "can't help but think — just hang on, there'll be something soon."
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    Michael J Fox introduced his Parkinson's disease foundation at the MaRS Centre in Toronto Sept 24, 2009.
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    Michael J Fox introduced his Parkinson's disease foundation at the MaRS Centre in Toronto Sept 24, 2009.
Assunta Krehl

MaRS Centre, Toronto - Intelligent Building of the Year - Canadian Consulting Engineer - 0 views

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    The MaRS Centre won the Intelligent Building of the Year award. This award.
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    The MaRS Centre wins the Intelligent Building of the Year award. Aug 1, 2006
Assunta Krehl

Changing Colours - BizBash - 0 views

  • Film Italia and the Italian Trade Commission's annual TIFF party took on a  chameleon theme set at the MaRS Discovery Centre.
  • The lower-key festival event, held at the MaRS Discovery District, attracted more than 400 people and took on a chameleon theme and slogan: "Try on the colours of Italian cinema."
  • “We try every year to shock people and to be a novelty,” said Italian trade commissioner Paolo Ponti of the party, which he planned in collaboration with Graham. Ponti said MaRS was chosen as a venue this year because of its melding of old and new and its representation of innovation. (The centre is known for leadership in science and business research.)
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  • The Italian Trade Commission chose MaRS as a venue for this year's TIFF party to represent innovation.
  • Rentals, Venue MaRS Discovery District
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    The Italian Trade Commission's Annual TIFF party was held at the MaRS Centre. More than 400 people attended the event. Sept 18, 2009
Assunta Krehl

Year in ideas: Stem-cell science grows up - National Post - 0 views

  • Gordon Keller, a senior stem-cell scientist who works out of Toronto's MaRS centre, also pointed to the potential for studying genetic diseases in a culture dish.
  • cientists have been working at a rapid pace over the past year to refine a process that allows them to replicate human embryonic stem cells, without the controversial use of a human embryo. It involves genetically reprogramming adult stem cells to an embryonic, or pluripotent, state.
  • Embryonic cells remain the "gold standard,"
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  • scientists have pinpointed a number of advantages IPS cells could have over embryonic cells.
  • Indeed, the International Society for Stem Cell Research teamed up with a number of leading scientists in September to issue an open letter reiterating the need for government support of all types of stem-cell research. The letter points out that research efforts on both embryonic and IPS cells "are in fact complementary and synergistic," noting that without the past decade of human embryonic stem-cell research, scientists would not have been able to realize their recent successes in reprogramming adult cells.
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    Scientists have been working at a rapid pace over the past year to refine a process that allows them to replicate human embryonic stem cells, without the controversial use of a human embryo. Mention of Gordon Keller, a senior stem-cell scientist working out of the MaRS centre.
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    Scientists have been working at a rapid pace over the past year to refine a process that allows them to replicate human embryonic stem cells, without the controversial use of a human embryo. Mention of Gordon Keller, a senior stem-cell scientist working out of the MaRS centre. Jan 2, 2009
Assunta Krehl

I had loads of fun at the MaRS District Entrepreneurship VC interview (Ochard, iNovia &... - 0 views

  • MaRS District Collaboration Centre in Toronto CIBC Presents Entrepreneurship 101. March 4th re-webcast of the session titled: How to Get Money From a VC Every entrepreneur wants to know the secrets for successfully pitching a VC or an angel. Join guest lecturer Peter Tolnai from Orchard Capital along with Chris Arsenault of iNovia Capital and Michael Midmer of Rosetta Capital, all prominent VCs who tell you their secrets for making a successful pitch.  They also host a Q&A session in which the panel  answers your questions directly without saying, "Come back in a few months when you've made some more revenue traction!"   http://www.marsdd.com/Events/Event-Calendar/Ent101/2009/what-investors-look-for-03042009.html
  • Last Wednesday I had the pleasure of participating in one of the MaRS District courses up in Toronto – CIBC Presents Entrepreneurship 101.
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    Arsenault's blog mentions about Entrepreneurship101 presentation on How to Get Money From a VC by Peter Tolani from Orchard Capital along with Chris Arsenault of iNovia Capital and Michael Midmer of Rosetta Capital at the MaRS Centre. March 9, 2009
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    Arsenault's blog mentions about Entrepreneurship101 presentation on How to Get Money From a VC by Peter Tolani from Orchard Capital along with Chris Arsenault of iNovia Capital and Michael Midmer of Rosetta Capital at the MaRS Centre.
Assunta Krehl

Doors Open Toronto - DayTrips.ca - 0 views

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    Mentions the MaRS Centre will be participating in Doors Open Toronto May 23 & 24, 2009.
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    Mentions the MaRS Centre will be participating in Doors Open Toronto May 23 & 24, 2009. March 26, 2009
Assunta Krehl

Media Advisory - Chief Medical Officer of Health releases report on 2008 listeriosis ou... - 0 views

  • : Collaboration Room 2 MaRS Centre 101 College Street Toronto, Ontario
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    Dr. David Williams, Ontario's Chief Medical Officer of Health, will release a report which reviews the way the public health system responded to last year's listeriosis outbreak. Mention press conference at the MaRS Centre.
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    Dr. David Williams, Ontario's Chief Medical Officer of Health, will release a report which reviews the way the public health system responded to last year's listeriosis outbreak. Mention press conference at the MaRS Centre. April 16, 2009
Assunta Krehl

Flashpoint News and Ratings - Moon Chase Blog Spot - 0 views

  • Ellis' Flashpoint
  • Toronto's MaRS Collaboration Centre,
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    Blog mentions Flashpoint episode "Business" was filmed at the MaRS Centre.
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    Blog mentions Flashpoint episode "Business" was filmed at the MaRS Centre. Feb 26, 2009
Assunta Krehl

A TIME'S MEMORY: Canada. Four cases of swine flu in Toronto area - hygimia69.blogspot - 0 views

  • Dr. David Williams, Ontario's acting medical officer of health announced the cases during a press conference downtown at the Mars Centre.
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    Dr. David Williams, Ontario's acting medical officer of health announced that there are 4 cases of the Swine flu in Toronto. Mention press conference at the MaRS Centre.
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    Dr. David Williams, Ontario's acting medical officer of health announced that there are 4 cases of the Swine flu in Toronto. Mention press conference at the MaRS Centre. April 28, 2009
Assunta Krehl

Four cases of swine flu in Toronto area - HealthZone.ca - 0 views

  • Dr. David Williams, Ontario's acting medical officer of health announced the cases during a press conference downtown at the Mars Centre.
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    Dr. David Williams, Ontario's acting medical officer of health announced that there are 4 cases of the Swine flu in Toronto. Mention press conference at the MaRS Centre.
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    Dr. David Williams, Ontario's acting medical officer of health announced that there are 4 cases of the Swine flu in Toronto. Mention press conference at the MaRS Centre. April 28, 2009
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