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We don’t know for sure,” said Dr. John Evans, chair of the board of directors at MARS (Medical and Related Sciences) Discovery District in Toronto, and vicechair of Mississauga, Ont.-based NPSAllelix Biopharmaceuticals, one of the pioneers of biotech in Canada. “But we believe that if you could ‘type’ the patient processes of how he/she handles a drug, you could peel off those people who would be particularly sensitive to a drug. Then you could find a sub-population where the drug is safe and highly effective.” Evans used the arthritis drug Vioxx as an example. It helped millions of people battle painful inflammation, but was pulled from the market recently because of potential cardiac side effects in some people. “If the drug company could have predicted which patients would have complications from Vioxx treatment — through some genetic profiling — then a very powerful and effective drug could have been preserved,” Evans said. His company, NPS-Allelix Bio-pharmaceuticals, has been developing a product since 1989 that will be launched later this year. The drug secretes a parathyroid hormone for treating osteoporosis.

It builds up bone matrix and helps build bone, rather than just delay bone loss as other drugs do.

The Caldwell Partners, Deloitte and National Post are pleased to announce the appointment of Gordon M. Nixon to Canada's Outstanding CEO of theYearTM Advisory Board for 2009.

Mr. Nixon is Chairman of the Canadian Council of Chief Executives, Chairman of MaRS Discovery District, and is on the Board of Directors of The Hospital for Sick Children, The International Monetary Conference, Catalyst Canada and is on the Advisory Board of Mercedes-Benz Canada.

The Toronto Region Immigrant Employment Council (TRIEC) is pleased to announce today's appointment of Gordon M. Nixon, president and chief executive officer of RBC, as Chair, and Zabeen Hirji, chief human resources officer of RBC, as Co-Chair of TRIEC.

As top executives at one of the largest financial institutions in North America, Gord Nixon and Zabeen Hirji are key ambassadors to articulate how Canadian companies can benefit from the international experience and networks, language skills and cultural knowledge that skilled immigrants bring with them to Canada."

Nixon has for years been a champion for promoting diversity in Canadian communities and of leveraging skilled immigrant talent as a driver of Canadian innovation and prosperity. Nixon is chairman of the Canadian Council of Chief Executives and chairman of MaRS Discovery District. In 2007, Nixon was invested into the Order of Ontario and was named Canada's Outstanding CEO of the Year.

My Charity Connects is part of Net Change Week – a week long city wide event put on by Mars Discovery District designed to dissolve the divide between digital professionals and social change-makers. Information about other exciting Net Change Week events can be found at http://netchangeweek.ca

Charles Plant of MaRS Discovery District, the innovation hub in Toronto. Charles communicates a rather negative view of venture capital, but it has the merit of presenting some of the important things to consider before seeking VC money.

I especially like the call to focus on customers first. This is not always possible, but designing for a defined market certainly is, and anyone involved with tech commercialization will tell you it’s often the exception rather than the rule.

Almost two years after Ottawa's 'Innovation Hub' was first proposed, documents show the province has serious concerns as to whether the Hub can garner enough private-sector support or will create enough jobs to qualify for funding.

The Hub is modelled after similar centres around the world, including the MaRS Discovery District in Toronto. But the concept has local critics, including Ottawa serial entrepreneur John Ogilvie, who said governments looking to promote innovation should focus on setting up commercialization facilities at universities.

Ontario's clean technology industry is poised for growth, and is comprised of companies that manufacture, develop and sell competitive products. Despite this promise, these companies face key challenges in becoming globally competitive - including lack of growth capital, weak domestic demand, and a small pool of management experienced in product commercialization.

Ogilvy Renault LLP, MaRS Discovery District, Blake, Cassels & Graydon LLP, Export Development Canada, RBC, Department of Foreign Affairs and International Trade, Ontario BioAuto Council, TMX Group Inc., Canada's Venture Capital & Private Equity Association, National Angel Capital Organization, XPV Capital and Investeco Capital.

"This investment underscores the government's recognition that Ontario must continue to invest in its strong life sciences cluster. Now more than ever, innovative research and development is a key driver, reshaping the knowledge economy and creating prosperity for all Ontarians." Dr. John Evans, Chair, MaRS Discovery District