Contents contributed and discussions participated by Nadeem Uddin
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'Viagra cream' could prove safer\nViagra\nSide-effects can include headaches, blurred vision and upset stomach\n\nA cream allowing erectile dysfunction drugs to be applied directly to the skin could one day make them safer to use, say New York scientists.\n\nStudies in rats suggest that Viagra, Levitra and Cialis could pass through the skin in tiny capsules, they say.\n\nThe research, published in the Journal of Sexual Medicine, could mean fewer side-effects, and even significantly speed up the drug's action.\n\nHowever, it could be a decade before creams are fully ready for use.\n\nThe arrival of erectile dysfunction treatments in tablet form has been one of the success stories of the modern pharmaceutical industry, with some estimates suggesting that tens of millions of men worldwide have used them.\n\nHowever, although they have worked for many men, they also carry the risk of side-effects such as headaches, blurred vision or upset stomachs.\n\nIn addition, men with severe heart problems, or who have just suffered a stroke, are advised to avoid the tablets altogether or use them with extreme caution.\n\nLess risk\n\nFor many, this could be solved by the development of the cream, with would confine more of the active ingredients of the drug to a single area of the body, rather than circulating them widely.\n \nThe response time to the nanoparticles was very short, just a few minutes, which is basically what people want in an erectile dysfunction medication\nDr Kelvin Davies\nStudy author\n\nThe research team at the Albert Einstein College of Medicine at Yeshiva University, in New York, used nanoparticles, each much smaller than a grain of pollen, and found a way to encapsulate particles of the drug inside.\n\nTheir early tests involved just a few rats bred to have erectile dysfunction later in life.\n\nOf these, 11 were treated with nanoparticles containing Cialis, a newer erectile dysfunction drug called sialorphin, and nitric oxide, a chemical also needed to wid
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