Though the software will sync information between two computers, highlights and notes created in NOOKStudy won't sync to the Nook, nor will highlights and notes created on the Nook sync to NOOKStudy. In fact, NOOKStudy couldn't even bring me to the correct page in the book I'm currently reading. At least the pages in NOOKStudy seem to correspond with the pagination you'd see on the Nook, so finding one's place isn't horrendously difficult, but still. Amazon had this sort of thing figured out with Whispersync some time ago.
