Influenza Research - 0 views
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Influenza viruses are important pathogens that can cause sporadic respiratory diseases, annual epidemics and (in case of influenza A virus) periodic pandemics
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Influenza researchers at five sites in the United States received funds from the American National Institute of Allergy and Infectious Diseases (NIAID) to collaborate with scientists worldwide in a network designed to advance understanding of influenza viruses – especially how they cause disease. The centers are based in Icahn School of Medicine at Mount Sinai (New York City), Emory University (Atlanta), St. Jude Children’s Research Hospital (Memphis), University of Rochester Medical Center (Rochester) and Johns Hopkins University (Baltimore).
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Two classes of antiviral medications are currently used for the treatment of influenza, but each has limitations in scope and its effectiveness.
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Antigenic diversity of the virus and constant influx of new subtypes allow the virus to become resistant to these antiviral drugs and evade vaccines. There is therefore a continuing need for new anti-influenza therapeutics using novel targets and creative strategies.
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An aggressive immune response known as the cytokine storm plays an important role in causing significant tissue injury and mortality following human pathogenic influenza virus
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bacterial infections in the lungGSK starts shipping FLUARIX
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infection
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most vaccine formulations for influenza are still produced by rather old-fashioned techniques that have been in use for over 60 years. Such methods involve the growth and passaging of the vaccine strains in embryonated chicken eggs, therefore production and subsequent formulation can take several months and rely
