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Sometimes, regular estrogen pills and creams wouldn't work when the body had suffered an extended degree of estrogen deficiency. Unlike regular estrogen creams with only Estriol as the main ingredient, Whole Family Products natural estrogen cream called BiEstro Cream is infused with Estradiol, a potent form of estrogen, to help replenish the body with the estrogen it needs.

Diindolylmethane, also known as DIM, is an activator of estrogen metabolism. It is a nutrient isolated from cruciferous vegetables that enhance the synthesis and breakdown of estrogen inside the body.