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On the occasion of World Sepsis Day, PAGB, the consumer healthcare association, has underscored the significant role that over-the-counter (OTC) antiseptics can play in preventing sepsis, potentially saving the NHS millions of pounds each year. Sepsis is a life-threatening condition where the body's immune system overreacts to an infection, causing damage to tissues and organs. Early recognition and treatment are crucial, as sepsis can rapidly escalate without prompt care. Symptoms of sepsis include confusion or slurred speech, fever, severe breathlessness, blotchy or mottled skin, and a lack of urination. PAGB emphasised that using OTC medicines early on can help prevent infections from worsening and potentially leading to serious conditions like sepsis. Michelle Riddalls, CEO of PAGB, stated: "Early prevention is always the best treatment for conditions that could potentially lead to sepsis. "If you don't get the right care for sepsis quickly it can be life-threatening so it's essential to seek immediate help if you or someone else has any symptoms.

The NHS has launched plans to expand pioneering subscription-style drug contracts to develop lifesaving antibiotics of the future. It is building on its world-first pilot to incentivise the pharmaceutical industry to develop new antibiotics that could be offered to NHS patients when they need them the most. The consultation has launched almost a year to the day that contracts for two superbug-busting drugs were rolled out as part of a world-first pilot. Cefiderocol and ceftazidime-avibactam, new antibiotics manufactured by Shionogi and Pfizer respectively, were awarded world-first subscription contracts which provided the companies with a fixed annual fee based primarily on the availability of the drugs and their value to the NHS, as opposed to the volumes used. By breaking the link between the payments companies receive and the number of their antibiotics prescribed, the NHS is removing any incentive to overuse antibiotics, decreasing the risk of life-threatening infections, such as sepsis and pneumonia, becoming resistant to treatment.