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Primary sclerosing cholangitis (PSC) is an uncommon chronic non-inflammatory disorder typically characterized by thickening, inflammation, and fibrosis of the bile tissues within the bile (septum) or the porcine bile duct (burgh's lobules). Both the apocrine and bile ducts are involved. The lining of the small intestine also becomes thickened. Patients generally have no symptoms. However, some symptoms may occur such as diarrhea, nausea, abdominal bloating, and vomiting. Other inflammatory diseases may co-occur with psoriasis. Primary sclerosing cholangitis is also called systemic sclerosis. It is one of the most common causes of cirrhosis of the liver in the U.S. In approximately one third of patients with PSC, no identifiable disease or infection is present. In approximately twenty-five percent of patients with this disorder, the disorder is diagnosed based on history and symptoms. In approximately ten percent of individuals with this disease, specific tests for an adequate diagnosis are not performed. Approximately two-thirds of individuals with PSC do not have a history of cancer or other systemic autoimmune diseases. Read more @ https://coherentmarketinsights-cmi.blogspot.com/2020/12/effective-treatment-is-need-of-hour-in.html