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The National Institute for Health and Care Excellence (NICE) today issued a draft guidance recommending dapagliflozin, sold under the brand name Forxiga among others, as an option for treating certain adults with chronic kidney disease (CKD). Dapagliflozin belongs to a group of medicines called sodium glucose co-transporter-2 (SGLT2) inhibitors. It is the first SGLT2 inhibitor to be recommended through NICE's technology appraisal process for CKD. Adding dapagliflozin to current standard care has been shown to significantly reduce the risk of having declining kidney function, end-stage kidney disease, or dying from causes related to the kidneys or cardiovascular system. "Dapagliflozin is a promising treatment for certain people with chronic kidney disease and it has the potential to increase the length of time before the disease gets worse," Meindert Boysen, deputy chief executive and director of the NICE Centre for Health Technology Evaluation, said.

E-pharmacy, a digital platform also known as internet pharmacy or online pharmacy, has emerged as an escape route to longstanding queues at pharmacy stores across almost all regions of the world, especially during the Covid-19 health crisis realm. They have long been recognised to act promptly in public health response, like ensuring an effective medicine supply system, resolving and monitoring drug shortage issues, educating about the proper use of PPE, promoting remote pharmacy services, and conducting drug evaluation and active surveillance. These factors will support in easing the load on healthcare facilities during the ongoing pandemic, eventually adding value to patients and the healthcare system. Overall, the e-pharmacy market size is expanding in terms of valuation on the back of regulations and standards laid by the respective governments. As per a recent study by Global Market Insights, the global e-pharmacy industry accounted for a business share of $68 billion in 2021 with an anticipated growth rate of 16.8 per cent through 2028.

As part of its inclusion and diversity strategy, the Royal Pharmaceutical Society (RPS) has launched a campaign to challenge barriers to working in pharmacy for those with disabilities. A profession-wide survey on the subject conducted by the RPS, identified disability as the biggest barrier to working in pharmacy, highlighting the area of work to support pharmacists. The campaign will focus on reducing barriers to enter the profession, developing more accessible working environments and encouraging employers to collect data on disability in the workplace. The campaign, based on inputs from the RPS Ability Group volunteers with visible and non-visible disabilities, will run until the end of March. Following recommendation of the RPS Ability Group, RPS has written to the General Pharmaceutical Council (GPhC) the Higher Education Occupational Practitioners (HEOPS) to update the guidance on standards of medical fitness for pharmacy students.

Britain has approved a new coronavirus vaccine by the Austrian-French drugmaker Valneva. "An approval has been granted after the Valneva Covid-19 vaccine was found to meet the required safety, quality and effectiveness standards," the Medicines and Healthcare products Regulatory Agency said in a statement on Thursday (April 14), adding: "It is also the first, whole-virus inactivated Covid-19 vaccine to gain regulatory approval in the UK." In vaccines such as Valneva's VLA2001, the virus is grown in a lab and then made completely inactive so that it cannot infect cells or replicate in the body but can still trigger an immune response. It is seen by some as having the potential to win over people wary of some which use new mRNA technology. Valneva CEO Thomas Lingelbach said that "this authorisation could pave the way for the availability of an alternative vaccine solution for the UK population."

Out of the 2,805 students who sat for the common registration assessment test for pharmacists this June, approximately 2,150 have passed the exam, according to the General Pharmaceutical Council. It assesses pharmacy graduates' knowledge and skills to ensure safe and effective practice as pharmacists. This year, the pass rate was 77 per cent, slightly lower than the 80 per cent pass rate in June 2022, where 2,147 out of 2,697 candidates cleared the assessment, GPhC data showed. The exam comprises a written assessment testing pharmaceutical science and pharmacy practice knowledge and a practical assessment evaluating clinical skills and patient-facing competencies. Eligible candidates must complete an accredited pharmacy degree program and meet GPhC requirements. The assessment is conducted jointly by the General Pharmaceutical Council and the Pharmaceutical Society of Northern Ireland. "The assessment is a primary method for testing trainees' ability to apply knowledge and make professional judgments in pharmacy practice," said Mark Voce, Director of Education and Standards, GPhC. "This is crucial in assuring patients and the public that they are in safe hands."

The Indian government has suspended manufacturing in over 40 pharmaceutical companies based on a risk-based assessment conducted earlier in the year across 162 firms, according to the data provided by Union Health Minister Mansukh Mandaviya in Parliament on Thursday (Aug. 10). "Overall, a sum of 143 show-cause notices has been issued," Mandaviya said. There have been numerous recent incidents involving accusations from foreign countries regarding the contamination of syrups, eye drops, and ointments manufactured in India. Countries such as the Gambia, Uzbekistan, and Cameroon have linked the deaths of 70, 18, and six children, respectively, to cough syrups contaminated in India. Licenses for specific products have been either temporarily suspended or fully revoked for an additional 66 companies. In one case, an FIR has been registered, and in 21 cases, warning letters have been issued following inspections by both the Central Drugs Standard Control Organization and State authorities, the Minister added. Meanwhile, the Indian government has mandated rigorous testing for cough syrups before export. Starting June 1, any cough syrup must possess a government laboratory-issued certificate of analysis before being exported, the government said in a notice dated May 22.

The General Pharmaceutical Council's Fitness-to-Practise (FtP) committee has reversed its earlier decision ruling that a London pharmacist's statement, attributing the Grenfell tragedy to "Zionist supporters of the Tory party," amounted to the propagation of anti-Semitic tropes. In an initial 2020 hearing, the FtP committee found that a set of remarks delivered by Nazim Hussain Ali, Managing Partner of Chelsea Pharmacy Medical Clinic, through a megaphone to a crowd assembled at a Palestinian rights rally in central London in 2017 were deemed "grossly offensive," but not classified as anti-Semitic. Ali admitted his comments were offensive, but he was cleared of accusations of antisemitism and received a first warning on November 5, 2020. However, the High Court overturned this decision in June 2021 following an appeal by the Professional Standards Authority as the Judge found evidence of a "serious procedural or other irregularity" in the FtP committee's decision and instructed the GPhC to reopen the case.

The Pharmacists' Defence Association (PDA) has begun conciliation with 86 pharmacy companies to safeguard the interests of former LloydsPharmacy pharmacists. The Advisory, Conciliation and Arbitration Service (Acas), a government agency, serves as a mediator between companies and employees to resolve disputes. If the ongoing mediation prove unsuccessful, individual employees retain the option to file claims in the employment tribunal, the PDA has said. The ongoing dispute centres around employers potentially failing to conduct the required consultation under the Transfer of Undertakings (Protection of Employment) regulations (TUPE) with employees and their representatives during employee transfers, the PDA said. The TUPE legislation, known for its complexity and technical nature, applies when a section of the company, like a pharmacy sold as an asset using standard disposal, undergoes a transfer. According to NHS England's recent pharmaceutical list, LloydsPharmacy has either sold or shuttered 461 branches since September 2022. According to NHSE data, as of June 30, the pharmacy chain operates approximately 512 pharmacies in England. This positions it as the third-largest chain after Boots UK and Well Pharmacy.

RP Healthcare, a multi-operator, has sold Hammersmith pharmacy in West London to an independent pharmacist for an undisclosed amount. "Mariam Moshref, owner of Fulham Pharmacy, together with her twin brothers, Arya and Jaan Moshref, purchased Hammersmith Pharmacy from Ravi Patel of RP Healthcare," Christie and Co, who handled the sale, said in a statement. This pharmacy operates during standard hours, handling an average of 5,920 items per month, the statement added. Refurbished in 2018, the pharmacy is located on Fulham Palace Road, W6, near Charing Cross Hospital and Hammersmith Underground station. RP Healthcare placed the pharmacy on the market as a strategic move to divest from the area.

The Medicines and Healthcare Products Regulatory Agency (MHRA) has approved the marketing authorisation of Adtralza, a dermatological solution developed by Danish specialist LEO Pharma. This injectable solution contains 300 mg of tralokinumab in a 2 mL pre-filled pen and will be available for tralokinumab patients in the UK from early 2024. Tralokinumab is indicated for treating moderate-to-severe atopic dermatitis in adult and adolescent patients aged 12 and older who require systemic therapy, Leo Pharma said in a statement. It is a fully human monoclonal antibody developed to specifically bind to and inhibit the IL-13 cytokine. Previously, it was available in a 150 mg in 1 mL pre-filled syringe. According to Leo Pharma, the 300 mg tralokinumab in a 2 mL pre-filled pen offers a streamlined administration for both patients and prescribers. It begins with an initial 600 mg dose in two injections, followed by a single 300 mg maintenance dose administered every other week. "We're pleased that this simplified administration method for tralokinumab will soon benefit eligible atopic dermatitis patients in the UK. It aligns with our commitment to elevate the standard of care and support for individuals with skin conditions," said Leanne Walsh, Vice President and General Manager of UK and Ireland at LEO Pharma.

The Pharmaceutical Services Negotiating Committee (PSNC) has reminded Community pharmacy contractors to ensure that the correct flu vaccines are being used for each patient cohort. The pharmacies have also been asked to ensure that they recorded accurately in the patient's clinical record for the NHS Flu Vaccination Service. The move was followed by PSNC after the cases where the standard egg-cultured quadrivalent influenza vaccine (QIVe) was administered in the 65 years and over patient cohort. PSNC said: "On investigation, it appears that a number of these errors are due to data input errors; however, it is important to be careful when selecting a flu vaccine for this patient cohort as there is no provision for the use of the QIVe vaccine in patients aged 65 years and over in the NHS Flu Vaccination Service." The Joint Committee on Vaccination and Immunisation has advised it is not an effective intervention for patients aged 65 years and over.

The Pharmacists' Defence Association (PDA) has raised concerns over "certain elements" of the Pharmaceutical Society of Northern Ireland (PSNI)'s consultation on pharmacy staffing levels. PSNI recently consulted on its draft guidance for pharmacy staffing levels which sets out to explain what pharmacy owners and superintendents must do to ensure that each pharmacy has enough skilled and qualified staff. This includes having an appropriate skill mix, to provide safe and effective pharmacy services which comply with the standards. PDA said that the role of the 'responsible pharmacist' has not been "fully acknowledged" and that more clarification is needed. The association has made a few recommendations to PSNI that includes: the guidance must explicitly recognise the statutory role of the responsible pharmacist and their authority in securing the safe operations within the pharmacy. "The guidance should specify that pharmacy owners and superintendents must ensure that they do not set incentives or targets which may compromise the professional judgement of staff." It also recommended that unregistered staff (including unregistered managers) are accountable firstly to the responsible pharmacist for any activity involving the clinical care of patients (for example unregistered managers must not interfere in diary bookings for vaccinations).

The Pharmacists' Defence Association (PDA) has submitted a 17-page contribution to the commission on the future of pharmacy professional leadership and encourages pharmacists to engage in the overall discussion. The association wants to ensure that the voice of its members is heard in the discussions about the future of professional leadership, which has been initiated by the four government Chief Pharmaceutical Officers. The PDA has published its first formal contribution to the commission, in its response it raised concern on the current exercise is being rushed and a call for the review to be conducted in a more sensible timeframe, one which enables the engagement of the whole profession. It has urged on being supportive of the creation of a Royal College of Pharmacists to take custodianship of the training and education for pharmacists and to set the requisite standards, whilst still relying upon the profession's regulators to undertake the accreditation role.

Well Pharmacy has announced a new partnership with RangeMe, a product discovery, sourcing and purchasing platform, as it looks to increase the diversity of products available to its customers. The independent pharmacy chain said the partnership will provide new, emerging and diverse brands increased access to its buying teams. There are already over 200,000 suppliers registered on the RangeMe platform. "We pride ourselves on being at the heart of the communities we serve and are delighted to be working with RangeMe to increase the diversity of the products we are able to offer to our customers across the UK," Reena Takhar, head of OTC & NHS buying at Well Pharmacy said. "Given the ongoing cost-of-living crisis, we're keen to do all we can to give businesses of all sizes the opportunity to connect with our buyersto allow us to offer new and interesting great value products to our customers." RangeMe helps retailers and their buying teams scale product sourcing efforts with streamlined submissions, simplified discovery tools, and the industry standard digital sell sheet.

On World Pharmacists' Day, the Council of the Pharmaceutical Society NI (PSNI) thanked pharmacists working in every sector of pharmacy in Northern Ireland (NI) for their continued service to the public. The theme of this year's International Pharmaceutical Federation's World Pharmacists' Day, (25 September 2022) was 'Pharmacy united in action for a healthier world'. In acknowledgement of the day, Dr. Jim Livingstone, president of the Council of the Pharmaceutical Society NI said: "The theme of this year's World Pharmacists' Day, 'Pharmacy united in action for a healthier world' highlights pharmacy's positive impact on health around the world and seeks to further strengthen solidarity amongst the profession. "In Northern Ireland, pharmacy played a prominent role in primary health care throughout the pandemic and remains the public's most trusted and accessible frontline health care profession. "As pharmacy continues to develop additional services for the public and encompasses broader roles for pharmacists than ever before, it is essential, no matter what pharmacy sector pharmacists practise in, that the Pharmaceutical Society NI's Code (Professional standards of conduct, ethics and performance for pharmacists in Northern Ireland) remains at the core of pharmacists' practice. It is through this adherence to the Code, that pharmacy remains a united profession, providing positive health outcomes for patients and maintaining public trust.