A smattering of monkeypox cases in Britain has prompted authorities to offer a smallpox vaccine to some healthcare workers and others who may have been exposed,
as a handful more cases were confirmed in parts of Europe.
Monkeypox is a usually mild viral illness, characterised by symptoms of fever as well as a distinctive bumpy rash.
There are two main strains: the Congo strain, which is more severe - with up to 10 per cent mortality - and the West African strain, which has a fatality rate of
about one per cent
First identified in monkeys, the viral disease typically spreads through close contact and largely occurs in west and central Africa. It has rarely spread elsewhere,
so this fresh spate of cases outside the continent has triggered concern.
In the United Kingdom, nine cases of the West African strain have been reported so far.
There isn't a specific vaccine for monkeypox, but a smallpox vaccine does offer some protection, a UK Health Security Agency (UKHSA) spokesperson said.
Data shows that vaccines that were used to eradicate smallpox are up to 85 per cent effective against monkeypox, according to the World Health Organisation.
A group of drugs commonly used to treat erectile dysfunction may be able to boost the effect of chemotherapy in oesophageal cancer, according to new research
funded by Cancer Research UK and the Medical Research Council.
The research, published on Tuesday (June 22) in Cell Reports Medicine, found that the drugs, known as PDE5 inhibitors can reverse chemotherapy resistance by
targeting cells called cancer-associated fibroblasts (CAFs) residing in the area surrounding the tumour.
Although this is early discovery research, PDE5 inhibitors combined with chemotherapy, may be able to shrink some oesophageal tumours more than chemotherapy could
alone, tackling chemotherapy resistance, which is one of the major challenges in treating oesophageal cancer.
Oesophageal cancer affects the food pipe that connects the mouth to the stomach, and while it is a relatively rare cancer, the UK has one of the higher rates in the
world, with 9,300 new oesophageal cancer cases in the UK every year.
Resistance to chemotherapy in oesophageal cancer is influenced by the tumour microenvironment, the area that sounds the tumour. This is made up of molecules, blood
vessels, and cells such as cancer associated fibroblasts (CAFs), which are important for tumour growth. It feeds the tumour and can act as a protective cloak,
preventing treatments like chemotherapy from having an effect.
Statistics show that 1 in 8 women will develop breast cancer at some point in their lives. While this disease can be deadly, it is also preventable. This
blog post will discuss six things you need to know about breast cancer prevention. Knowledge is power when it comes to fighting cancer, so read on and learn how
you can protect yourself.
UNDERGO ROUTINE CHECKUPS
One of the first things you can do to prevent breast cancer is to undergo routine checkups. This means going for mammograms and clinical breast exams regularly. In
this case, your doctor may even recommend using ultrasound technology to get a clear picture of the breast tissue. Rest assured that your doctor will be able to
detect any changes in your breasts and will be able to determine if there is anything to worry about. The earlier you catch any abnormalities, the better your chances
of beating cancer.
BE AWARE OF YOUR FAMILY HISTORY
Another important factor to consider is your family history. If you have close relatives who have been diagnosed with breast cancer, your risk may be higher. This is
because some forms of breast cancer can be hereditary. As such, it is important to be aware of your family history and to let your doctor know if there is a history
of breast cancer in your family. From there, you should discuss your options with your doctor and make sure to get regular screenings. More often than not, early
detection is key when it comes to surviving breast cancer which is why family history is so important.
Ninety-six per cent of community pharmacists surveyed in the Royal Pharmaceutical Society (RPS) Workforce Wellbeing survey said they were at 'risk of burnout'.
A higher number of respondents working in community pharmacy (20%) reported not being offered breaks compared to all other sectors (8%) and were more likely to
experience verbal or physical abuse from patients and the public (69% vs an average 44%).
The annual Workforce Wellbeing survey also revealed that 88 per cent of pharmacists surveyed are at high risk of burnout due to winter pressure. Therefore, RPS is
calling for workforce planning for pharmacy to address skill mix and staffing levels so that workloads can be effectively managed.
Top factors causing poor mental health and wellbeing revealed by the survey include inadequate staffing (70%), lack of work/life balance (53%), lack of protected
learning time (48%) and lack of colleague/senior support (47%).
This is the fourth survey RPS has run in partnership with the charity Pharmacist Support on the state of mental health and wellbeing in pharmacy.
The findings demonstrate continued pressure on pharmacists and trainees across the workforce, especially in community pharmacy where 96% of those surveyed said they
were at risk of burnout.
WHAT IS PROTEINASE K MADE OF?
Proteinase K is known enzyme belonging to the class of serine proteases that cleave adjacent to the carboxylic group peptide bonds of aromatic and aliphatic amino
acids. It's also exhibited a very broad cleavage specificity. The enzyme was discovered in extracts of the fungus Engyodontium album.
HOW DOES PROTEINASE K WORK?
In molecular biology, main application of proteinase K is to digest proteins during nucleic acids purification in order to remove protein contaminants:
- Proteinase K quickly inactivates nucleases (enzymes that digest nucleic acids) that degrade DNA or RNA molecules during the cleansing.
- Proteinase K is activated by calcium. It does not affect the activity of the proteinase, but protects again autolysis, improves thermal stability, and regulates
substrate binding capacity. To increase the stability of Proteinase K, thereby enhancing its action, Urea as well as SDS (sodium dodecyl sulfate) or elevated
temperature at 37-60C is commonly used. Inactivation of Proteinase K is occurring at temperature above 65C.
WHAT IS THE PURPOSE OF PROTEINASES?
Proteinase K is used to break down proteins in cell lysates (tissues, cell culture cells) and to release nucleic acids due to its action described above. Proteinase K
application purpose:
DNA isolation from various tissues;
Removal of DNAses and RNAses: Proteinase K and RNases can act together in the lysis buffer to degrades contaminating RNAs and proteins;
Margaret MacRury has stepped down from her role as superintendent director for the Rowlands Pharmacy, which has a community pharmacy network in England,Scotland and Wales with more than 450 branches.
MacRury, who served the role for a decade, will step down next month to focus on the pharmacy contract developments taking place in Scotland, Rowlands said in a statement.
She will start her new role in February 2022.
With MacRury leaving the position, Stephen Thomas, currently her deputy, will take up the role of superintendent for Rowlands. He has been with the multiple for nearly 18 years and has worked side-by-side with MacRury for the last decade.
MacRury stated: "I know Stephen will continue that commitment to protecting patients and promoting the pharmacy sector.
The Pharmacists' Defence Association raised concerns over the practice of firing and rehiring employees, which often leads to denial of individuals' rights to redundancy, forcing them to face cuts to their terms and conditions.
It noted that some employers may use the 'fire and rehire' practice to force staff to accept lower wages, different hours, or other changes in working conditions.
It cited an example of a lawsuit in which Tesco lost a High Court battle when Usdaw won a case to protect workers from unfair tactics.
The PDA said although the trade union won the case, the practice of firing and rehiring can still be legal in some circumstances. However, it believes the practice is both immoral and unethical.
Have you ever wondered about the health benefits of ginseng? It's been used for thousands of years by people in Asia and Eastern Europe, but did you know it's good for more than just boosting energy? The ginseng plant deals with 11 combinations of short, slowly growing plants with fleshy roots. It can revive and improve well-being. This article will explore how this herbal plant can benefit your body.
11 Health Benefits of the Ginseng Plant
There are two types of ginseng plants mainly:
Asian or Korean ginseng (Panax ginseng)
American ginseng (Panax quinquefolius).
Studies have discovered that the distinct types have various uses. American ginseng is believed to be less stimulating in traditional Chinese medicine than the Asian one. There are several other herbs known as ginseng, like eleuthero or Siberian ginseng, but they don't have the valuable content of ginsenosides. Ginseng has traditionally been used for several medical illnesses. However, its benefits for most of them have yet to be thoughtfully researched. These include:
1/11_It may help your lungs work better.
ginseng plant lowers lungs infections.Ginseng may also help your lungs, according to a published study in the Journal of Ethnopharmacology.
Researchers found that one of the active ingredients in ginseng, ginsenoside Rg1 has an anti-inflammatory effect on the lungs and can even protect against asthma and bronchitis.
They found that rats with asthma had less inflammation after being given doses of ginseng for two weeks compared to rats not given any. They also observed that rats with pneumonia had fewer symptoms when they were treated with inhaled doses of ginsenoside Rg1 or orally administered doses of Korean red ginseng extract (KRGE).
2/11_It may lower blood sugar levels.
ginseng plant lower blood sugar levels.
It's not just your imagination-ginseng can help lower blood sugar levels in people with diabetes. It also has been proven to reduce the amount of cholesterol in your body. It
Every day, we all struggle for a balance in life, but how many of us endeavor for it?
When we care about our health, we take steps to protect it, we try to eat right, exercise more, and sleep better. But sometimes even after trying hard and putting a lot of effort to adopt a hearty and healthful life, we lack.
We all need nutrients from our diet but sadly, we don't live in a perfect world that can supply these essential supplements and nutrients.
That's where the need for multivitamin tablets in india takes over to fill our nutrient deficiencies, stress, sleep disorder, and various other complications.
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Northern Ireland will see changes in the regulatory landscape following the issuance of the Windsor Framework on 27th Feb 2023 and the corresponding EU
Commission proposal. An agreement, in principle, has been reached by the UK and EU.
The new path forward of the Windsor Framework marks a turning point in how both the UK and the EU will work together collaboratively and constructively to ensure
that the same medicines are available in Northern Ireland at the same time as they are in the rest of the United Kingdom.
Whilst this is a successful result for Northern Ireland patients, this is major change for companies that have made specific provisions in their supply chains for
Northern Ireland. The supply chains of companies where provisions and changes were made such as introduction of GB specific pack may be impacted as a result.
However, the burden on the UK Pharma supply chain will be eased.
Prime Minister Rishi Sunak walks with European Commission chief Ursula von der Leyen in Windsor on February 27, 2023
Pharma companies will need to carefully consider making changes within their processes and supply chains pending the issuance of clear guidance from the MHRA on
the regulation changes resulting from the Windsor Agreement and the corresponding EU Commission proposed regulatory changes associated with medicinal products
within the Northern Ireland market.
Smooth access to the EU market for Northern Ireland pharmaceutical and medical technology firms has been safeguarded within the constraints of the agreement. The
pragmatic dual-regulatory system protects business, patients and healthcare services, and reflects that it is an essential state function to maintain and oversee
the supply of medicines within the whole United Kingdom.
If you want to start your day feeling refreshed and energized, consider creating a daily regimen of ginger shots instead! Ginger shots are like taking ginger ale straight to the source. They give you all sorts of vitamins, minerals, and antioxidants your body needs to feel its best. These shots are beverages made from concentrated doses of ginger root (Zingiber officinale), which are asserted to aid in warding off sickness and strengthen your resilience against many health conditions. However, ginger shots just became prevalent recently in the wellness society; ginger brews have been used since ancient times to cure a host of ailments. While ginger presents unique health features, you may wonder whether sipping ginger shots is healthful.
This article inspects ginger shots, including their potential health benefits, side effects, and preparation at home.
Ginger Shots
Ginger shots are potent drinks made with fresh ginger root. The ingredients used in the shot differ depending on the recipe you want to try. Some shots include only fresh ginger juice, while others comprise lemon juice, orange juice, turmeric, cayenne pepper, and/or manuka honey. You can make it at home by squeezing fresh ginger root juice or blending fresh, grated ginger with different juices, like lemon or orange. Now you can see that these shots are available pre-made or made to take away at juicers or health food stores.
You can also beat them up at home by operating a juicer machine. For this, just add freshly grated ginger to citrus juice or mix a dash of ginger with other ingredients in a high-powered blending pot.
You may find ginger shots spicy and unpleasant to drink owing to their high content of ginger roots. Hence, they're made in small amounts and generally drunk in one or two swigs.
Ginger Root
Ginger root has been used medicinally for thousands of years. The ancient Chinese used it to treat stomach problems, colds, and inflammation. According to the National Institute of Health (NIH
The Pharmacists Defence Association (PDA) has welcomed the government's action of publishing 'AI Regulation White Paper' which will regulate the artificial
intelligence (AI) system used in pharmacy on Wednesday (29 March).
The Association had raised concerns about the risk of patient harm due to inappropriate use of so-called AI to include that seen in some of the pharmacy systems
undertaking clinical checks.
For some time, it has been receiving concerns from practicing pharmacists describing examples of the potentially detrimental impact of automation and online pharmacy
provision on patient safety and pharmacy practice.
As a result, it raised these concerns with regulators, Chief Pharmaceutical Officers, and parliamentarians in all four nations of the UK to urge action.
It said: "This is required not only to protect patients, but also the frontline pharmacists who could be blamed for potential harm caused by inappropriate use of so
called 'AI' systems implemented by their employer."
The PDA therefore, welcomes the announcement from the UK government that they intend to strengthen regulation of such technology, empowering existing regulators to
come up with tailored, context-specific approaches that suit the way AI is actually being used in their sectors; this will include pharmacy.
Organic Turmeric powder has long been used as a natural beauty agent as it is used to make a paste and face masks for treating various skin issues till now. As per the latest research, turmeric Soap helps banish dark spots and hyperpigmentation. Also, a study published in the journal of clinical and aesthetic dermatology affirms that topical turmeric curcumin extract in a moisturizing cream and soap formula reduces the appearance of facial spots, fine lines, aging, and wrinkles on human facial skin. Also, it was found that hyperpigmentation can be reduced by 14-15% within four to five weeks of turmeric-based skincare products. Being a natural ingredient, turmeric soap is safe for all skin types and is even recommended for people with skin conditions. So let's further explain why this is so good for you.
Naturally, turmeric is rich in antioxidants and antibacterial properties. The antibacterial and antioxidant content in turmeric battle acne, whereas the mighty antioxidant makes the skin tone clear. And the same properties go for turmeric used in soaps.
Is turmeric soap good for your face?
Yes, turmeric soap is virtually good for your face because modern dermatologists have explored its positive and healthy effects on the skin. On the other hand, it is becoming famous because of its beneficial impacts on the skin.
Turmeric soap benefits for skin
Backed by clinically proven research, this skin-healthy soap has the following benefits:
1. Antiseptic, Anti-bacterial & Anti-inflammatory Soap
Turmeric is a known herb that treats acne. This is because it boasts natural antiseptic and anti-inflammatory qualities that prevent clogged pores and stop the growth of acne-causing bacteria while reducing redness and inflammation. As an anti-inflammatory agent, it can help calm the skin and prevent long-term acne scars. Anti-bacterial content in turmeric arrest acne breakout and prevents further infection both for skin as well as oral health. You must add this soap to your ski
Dark spots or hyperpigmentation might force you to pick skin-bleaching products to even skin tone, but their results can be the least, and the odds are doubled. Applying sunscreen daily and articulate with a dermatologist is the easiest way to protect your skin from dark spots. But if you want to pick a natural alternative for dark spots or hyperpigmentation, what could be a better natural alternative than spice turmeric?
Yes, TURMERIC SOAP FOR DARK SPOTS. You may wonder why turmeric retard the melanin production in your skin cells because melanin is the pigment that forms dark spots and other types of hyperpigmentation. Using turmeric-oriented products or turmeric soap benefits uneven skin naturally. After three to eight weeks, you'll see that turmeric soap is fading the dark spots and giving your skin a more even-toned impression!
Hyperpigmentation, or dark spots, can be induced by acne scars, extreme sun openness, or hormonal shifts, according to Dr. Asim Sohail, Dermatologist, Cosmetologist, M.B.B.S., M.C.P.S. (Dermatology), A.A.C.M.E. (U.S.A.), Professional Diploma in facial aesthetics.
The market is full of various creams and serums that patients often utilize to help fade, brighten, and even dark spots over time," he said. Each of these therapeutic choices may put you at risk. Read on to uncover which alternative may work best in your case.
Turmeric Soap For Dark Spots:
A 2018 Journal of Clinical and Aesthetic Dermatology review found that natural ingredients effectively manage dark spots or hyperpigmentation. Among these natural ingredients, turmeric was proven to reduce the appearance of dark spots within four weeks of usage. However, due to the shortage of clinical studies on the issue, turmeric's skin-lightening benefits have yet to be resolved.
READ MORE
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https://amvital.com/turmeric-soap-for-dark-spots-know-the-truth/?v=1d20b5ff1ee9
PSNC has urged community pharmacy contractors and LPCs to engage with their local MPs on the immense pressures that pharmacies are facing.
The organisaiton has also published some new resources to help pharmacists in this regard.
"PSNC is deeply aware of the funding crisis affecting the sector and is working hard to increase the pressure on [the] government to act now with an urgent funding
uplift. This has included upping investment in influencing activities and working closely with LPCs to take united action," it said.
PSNC has last month launched its Four Point Plan to safeguard the future of community pharmacy, setting out how pharmacy could be the solution to a number of
problems if, and only if, it is properly funded, resourced and supported.
As pressures continue to mount, further briefings now focus solely on the urgent need to resolve the funding squeeze in order to protect existing pharmacy services.
Maintaining good personal hygiene is among the most effective defenses against gastrointestinal and infectious disorders such as the flu, and the common cold.
By using soap and water to wash your hands, you can prevent the spread of germs that can make you sick.
When it comes to your own health, basic personal hygiene can also assist protect you from infecting others. A typical personal hygiene consists of following habits:
Every day, washing your face and body
Washing your hands after using the bathroom with soap
Twice daily cleaning of the teeth
When you sneeze or cough, using a tissue (or your sleeve) to cover your mouth and nose
After touching pets and other animals, cleaning your hands
Here's what you can do to reduce the spread of infection through a basic personal hygiene:
Keeping Food In A Safe Environment
Before and after cooking, wash your hands. Thus, you won't be able to contaminate food and won't get sick or spread bacteria from food, such as raw meat
One type of bacteria found in the gut may contribute to the development of Type 2 diabetes, while another may protect from the disease, according to early
results from an ongoing, prospective study led by investigators at Cedars-Sinai.
The study, published in the peer-reviewed journal Diabetes, found people with higher levels of a bacterium called Coprococcus tended to have higher insulin
sensitivity, while those whose microbiomes had higher levels of the bacterium Flavonifractor tended to have lower insulin sensitivity.
Mark Goodarzi, the director of the Endocrine Genetics Laboratory at Cedars-Sinai in Los Angeles, California, is leading an ongoing study that is following and
observing people at risk for diabetes to learn whether those with lower levels of these bacteria develop the disease.
"The big question we're hoping to address is: Did the microbiome differences cause diabetes, or did diabetes cause the microbiome differences?" said Goodarzi, who
is the senior author of the study and principal investigator of the multicenter study called Microbiome and Insulin Longitudinal Evaluation Study (MILES).
In response to Thursday (5 January)'s announcement on the proposal of new 'anti-strike' legislation, the Pharmacists Defence Association (PDA) has said that
it will work with other trade unions to defend the fundamental right for workers in the sector to strike.
The association believes that "industrial action should always be a last resort, especially for health professionals such as pharmacists, however having the option
to strike is a fundamental right for working people in a fair and free, civilised society."
"The right to strike is a fundamental right through which employees can act collectively to secure and protect pay and conditions."
It added: "The Trade Union Congress (TUC) are coordinating the challenge to these proposals."
The TUC said in a statement: "The Prime Minister should concentrate on fixing our public services, not attacking public sector staff. The proposed legislation would
make it harder for disputes to be resolved."
The Medicines and Healthcare products Regulatory Agency (MHRA) on Wednesday (9 January) announced that the novel type 2 oral polio vaccine (nOPV2) has been
quality-assured (prequalified) by the World Health Organization (WHO).
Developed by a team including scientists from the MHRA, nOPV2 is considered a safer polio vaccine that helps to protect children from the disabling and
life-threatening disease and lower the risk of vaccine-derived outbreaks.
The vaccine received WHO Emergency Use Listing three years ago, and since then 950 million doses have been delivered worldwide.
The UN health agency's decision to add it to the list of prequalified vaccines is based on the analysis of outcomes in vaccinated populations that has confirmed
strong safety profile and effectiveness.
