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The Company Chemists' Association (CCA)'s research has found that between 2015 and 2022 more than 40 per cent of permanent community pharmacy closures took place in the 20 per cent most deprived parts of England. The association has analysed the NHS data and found that between 2015 and 2022, 808 pharmacies closed permanently in England. In that period, only 138 new pharmacies opened - a net loss of 670 community pharmacies. It also examined where permanent closures had taken place. "41% of net permanent closures had taken place in the top 20% most deprived areas in England. Meanwhile, only 9% of net permanent closures took place in the top 20% least deprived areas." Although the latest figures for 2021/22 suggest that the overall rate of closures may be slowing down, the proportion of pharmacies permanently shutting in more deprived areas has only increased. An even larger share of pharmacies that permanently shut in 2021/22 occurred in the most deprived areas compared with the previous fiscal year: 44% of net closures took place within the bottom two IMD deciles.

Department of Health and Social Care (DHSC) has increased the rate of discount deduction for generics from 17.52 per cent to 20 per cent. The Drug Tariff for April 2023 will contain changes to the discount deduction arrangements for pharmacy contractors, which will include- all concession lines to be considered as Group Items for Discount Not Deducted i.e. DND or zero discount (ZD) items; and rate of discount deduction for generics to increase from 17.52% to 20% The Pharmaceutical Services Negotiating Committee (PSNC) and DHSC agreed on the changes for all concession lines to be considered as Group Items for Discount Not Deducted. Therefore from 1 April 2023, a new category will be introduced into Part II of the Drug Tariff 'Drugs for which discount is not deducted'. However, the committee had rejected the changes in the rate of discount deduction for generics. It said, "Following pressure from NHS England, Ministers have now chosen to impose changes to the previously agreed discount deduction arrangements, which come into effect from 1 April, and will be kept under review."

Are you looking for an easy way to lose 20 pounds fast? As we all know, the best way to lose weight slowly is to change your diet while incorporating a right exercise routine. But what if you need to drop 20 pounds fast? In this article, I will introduce you a new fat burning method which you could lose 20 pounds fast right at the comfort of your own home. Take just 2 minutes out of your busy day to read this article and learn more about it.

Selection of portable travel wheelchairs, utilizing small caster wheel and lightweight materials, can tip the scale at as little as 13 lbs! Like transport chairs, travel chairs are geared towards storability and portability, but they're even more convenient for those on-the-go. These chairs feature four smaller wheels, rather than the large rear-mounted wheels that characterize standard wheelchairs, and their design ensures that they're always foldable and convenient to carry. Whether it's a family vacation, or a good ol' fashioned road trip, these lightweight wheelchairs are best bet. Lightweight travel wheelchairs give the most independence of movement with the least amount of effort. This type of wheelchair is recommended for someone who cannot self-propel in a standard wheelchair. The weight of this type wheelchair ranges from 28-34 pounds. Lightweight wheelchair is for the highly active individual as they are more easily maneuverable and durable. This type wheelchair weighs in as low as 14 pounds. This helps with ease of use and transport. Travel wheelchair assists people to become more mobile and independent. There are many different types of wheelchairs that are used for various reasons. It is important to understand the limitations and safe operation of whatever wheelchair choose or need. The travel chair seat size (width and depth), seat-to-floor height, footrests/leg rests, front caster outriggers, adjustable backrests, controls, and many other features can be customized on, or added to, many basic models, while some users, often those with specialised needs, may have wheelchairs custom-built. A single-arm drive enables the user to turn either left or right while the two-armed drive enables user to move forward or backward on a straight line. Another type of wheelchair commonly used is a lever-drive wheelchair. This type of chair enables the user to move forward by pumping the lever back and forth. Travel Wheelchairs are usually designed fo

Lightweight travel wheelchair is a Transport Wheelchair that has a lightweight frame and many features that are common on Transporters.Light travel wheelchairs are great for road trips and travel tours, you can go anywhere with a Travel chair, the frame is light and easy to fold and store, this type of wheelchair fits easily into the trunk of your car, or if you are traveling by plane, bus, or train. We provide Lightweight Travel Wheelchair that are dependable and easy to carry or fold, our Transport Wheelchair Series includes travel wheelchairs that have many unique features. We also carry the original and upgraded "Airplane Wheelchair", which is specifically used for plane travel, meaning that it was designed to fit in an airplane, through the aisles and through the doors, and through the bridge.

Transport chairs, also known as companion wheelchairs, have four small wheels instead of two small and two large. A transport chair is designed to only be push by caregiver, other common names are 'companion chair' or 'rollabout chair'. A huge variety of different widths and weight capacities are available. A transport wheelchair is a mobility chair designed for convenience, short-distance use and easy handling by a caregiver. Lightweight and foldable, these wheelchairs are easily moved and typically fit in the trunk of most vehicles. There is even a model designed to fold into a bag to be carried over the shoulder. They are much smaller than standard manual wheelchairs and similar in size to the front wheels. Without large rear wheels, the user must rely on someone else to push the chair, which is why the transport chair is often referred to as a companion wheelchair. Karma Travel Wheelchair KM TV 20.2: Karma Travel Wheelchair KM TV 20.2 - 606 T-6 aircraft-grade aluminum-alloy frame provides incredible strength. Easy-to-fold in three seconds. Karma Travel Wheelchair KM TV 20.2 Features: Type: Travel Wheelchair T-6 aircraft-grade aluminum Secure brake improve safety Padded flip back armrest PU front caster & rear wheel Karma Travel Wheelchair KM TV 20.2 Measurements: Weight: 8.9kg Seat width: 39.5cm Tyre: PU front casters and rear wheels Capacity: 100kg Folded size: (L/W/H): 610mm x 350mm x710mm. Ultra Lightweight Wheelchair: Its compact design and feather light weight makes it suitable for people on the go. Ultra Lightweight Wheelchair Specifications: Frame Style : Foldable Frame Material : Aluminium (Light weight) Rear wheel to wheel width in open position (inches) : 20" Handle to Handle : 16" Seat Width (inches): 13" Rear Wheel Size: 7" Front Wheel Size: 5" Seat to floor height (inches): 19" Seat Depth (inches): 13" Back height (inches): 16" Total height (inches): 35" Max User Weight Capacity (kgs): 80 k.g. Net Weigh

Travel Wheelchair for handicapped and disabled at lowest price and cheap cost in india shope online for Transport Wheel Chair manufacturer distributor dealer and supplier of variety of Travel Wheelchair at low price in india for handicapped and disability product like Karma KM 2500 L Wheelchair, Karma KM 2500 Small Wheel Wheelchair, Karma Travel Wheelchair KM TV 20-2, Ultra Lightweight Wheelchair along with that we offer huge discount and promo code when you purchase TRAVEL WHEELCHAIR from our online shopping store of Travel Wheelchair. Km 2500 Wheelchair Specifications: Width 18" Front/Rear Wheels 6" to 14" Seat Width 47cm Seat Depth 40cm Overall Width 66cm Overall Collapsed Width 36cm Armrest Height 21cm Overall Length 90cm Seat Height 47cm Backrest Height 38cm Overall Height 86cm Weight 9.2 k.g. Km 2500 Wheelchair Price: Item Code: WCI-20 MRP: Rs 20517 Our Price: Rs 14500 Net Price: Rs 14210( Apply Coupon Code 'MSW2365' Get 2% Discount ) KM 2500 Wheelchair @ Rs 14210 supplier, distributor and dealer of Karma KM 2500 Wheelchair for disabled and handicapped in india, Buy Karma Premium Wheelchair KM-2500, Karma KM 2500 Online Shopping, Karma KM 2500 Price, Karma KM 2500 Small Wheel Wheelchair For Sale, Karma KM 2500 Small Wheel Wheelchair For handicap. Wheelchairindia.com C/O Manish Steel Works is an India based online handicapped product shopping website offers a large variety of handicap products and at amazingly low prices. Avail benefit of latest promotions on Wheelchairs, Tricyle, handicap walker, handicap crutches, handicap sticks, folding commode, cycle rickshaw, handicap moped and other items.

how to lose 20 pounds, A healthy and balanced diet loses you 20 kg in two weeks and is suitable for heavy weights above 90 kg.

Karma ErgoLite Lightweight Transporter Chair is a portable mobility solution that is lightweight and foldable so you can bring it everywhere.S-2501 ErgoLite is highly manueverable, providing convenient transport whether you are in class, visiting the doctor or just enjoying time with friends at the mall. Karma Ergolite 2501 is designed for comfort and convenience,Ergolite has fixed armrests with padded troughs, fixed footrests with wider footplates and three pouches for storing personal items while you are out. If you want a mobility aid that combines a durable, low-profile frame with satisfying ergonomics, buy the Karman Healthcare ErgoLite Lightweight Transporter Chair from ActiveForever.The pressure-minimizing ergonomic seat means you can ride for an extended time and remain comfortable and safe from skin ulceration. The built-in seat cushion is treated with Aeigs Microbe Shield technology, rendering it permanently anti-bacterially active for added skin protection. This long-lasting transporter chair has aircraft-grade aluminum for a frame and rugged, 14" tires that never go flat. Karman Healthcare offers an unbeatable lifetime warranty on its S-ERGO line of chairs so you know you're getting a high-quality product. Karma Ergolite 2501 Lightweight Transporter Chair Features: 18 pound transport chair is lightest available S-style ergonomic seat minimizes pressure Aircraft-grade aluminum frame Flat-free tires Backrest folds for easy transport in car Hand brake works with light grip Wider footplates Three pouches for personal items Separate brake for caregiver Built-in anti-microbial cushion

Ergonomic wheelchair series provides users with a large selection of ultra lightweight wheelchairs that can help improve life. This series has features that include a high strength lightweight frame, foldable and easy to store, breathable anti-bacterial, anti-staining, removable and machine washable cushion. Also includes the exclusive S-Shape Seating System, which provides increased stability, better weight distribution and lowers the risk of pressure sores and spinal injury. The patented S-Shape Seating System that comes with every wheelchair model in this series provides an ergonomic seating frame that conforms and flexes to the shape of body. Karma S Ergo 115 Wheelchair: This model features our S-Shape Seating System and is our number one best seller for many reasons. At a mere 11.3 kg in weight with detachable foot rest and many features such as removable machine washable and dry-able cushions treated by AEIGIS treated anti-microbial coated seating system. Karma S-Ergo 115 Wheelchair Features: Ergonomic Handrims & S-Shape Ergonomic Seating System Fixed armrest w/ wider concave armpads Swing In & Away Footrests Backrest Pouch attached to the upholstery 24" flat free polyurethane tires, high tread, flat free wheels Seat width: 16"x17" or 18"x17" or 20"x 17" Silver 1/4" Aegis Anti-Bacterial Upholstery, washable Folding backrest / folding seat for easy traveling "Tube-in Center" foot-plate, assures better side leg support High strength, starting weight at only 11.3 kg. (w/o footrests) 7×1" Polyurethane front casters Upholstery: Black breathable mesh bottom & top AEIGIS Frame Color: Pearl Silver or Rose Red Weight Capacity of 115 kg. Karma S-Ergo 115 Wheelchair Measurements: Seat Width 16 inch., 18 inch., 20 inch. Seat Depth 17 inch. Armrest Height 8 inch. Seat Height 19 inch. Back Height 17 inch. Overall Height 36 inch. Overall Open Width 23 inch., 25 inch., 27 inch. Folded Width 12 inch. Overall Length 39 i

A Pediatric Wheelchair is a very important piece of mobility equipment for any patient. There are many instances where a patient would find himself in need of one, no just in cases of long-term disability. Upon admittance and discharge from the hospital, a patient is wheeled around. Those with temporary hurts to their lower extremities will also need a Pediatric Wheelchair for a short time. No matter the reasons for needing a Pediatric Wheelchair, many will find themselves looking for the right one for themselves, their patients, or for their medical care facility. For a pediatrician seeking to prescribe a Pediatric Wheelchair, must be sure that the patient has the proper upper body strength to use one. If the patient is too weak for self movement, the practitioner would be better to consider a powered wheelchair for mobility. While Pediatric Wheelchairs are smaller and can be just as manuverable as scooters, that depends upon the patient's own abilities in steering the chair. These are factors that the doctor must think about before recommending what type of wheelchair a patient should get. Cerebral Palsy Wheelchair: Cerebral Palsy Wheelchair Description: The model designed for cerebral palsy child only. Ultra light weight aluminium alloy frame Seat Width 38 cms (15") Net Weight: 18.5 kgs Epoxy powder coated frame Detachable arm rest & foot rest provided Elevated and swinging foot rest Elevated foot rest provided to elevate leg angle Height adjustable and detachable head rest Hydraulic reclining high back for a comfortable posture Hydraulic adjustable seat angle Detachable back and seat pad Extra cushion upholstery provided to under arm, head & calg Foldable Lever and paddle brakes provided Safety belt provided Maintenance free rear solid wheels Cloth look like water proof upholstery Anti wheels for better safety and stability Extra cushion upholstery provided to under arm, head & leg Folding action Lever and paddle brakes provided

Km 2500 Wheelchair is amazingly light and compact transit wheelchair which is ideal for outings and travelers. It folds down to take up virtually no space in the boot of a car and weighs just over 9kg making it easy for anyone to lift into a vehicle. It is built with an ultra-lightweight aircraft-grade aluminum alloy frame with a standard seat width of: 16"" and 18"", it has a foldable frame with dual brake system and 20"" flat-free rear wheels. Ultra-lightweight aircraft-grade aluminum alloy frame Standard seat width: 16"" and 18"" Foldable frame with dual brake system 20"" flat-free rear wheels Attendant cable brake Detachable and washable cushion. KARMA KM 2500 SMALL WHEEL WHEELCHAIR: Karma KM 2500 Small Wheel Wheelchair Specifications: Width 18" Front/Rear Wheels 6" to 14" Seat Width 47cm Seat Depth 40cm Overall Width 66cm Overall Collapsed Width 36cm Armrest Height 21cm Overall Length 90cm Seat Height 47cm Backrest Height 38cm Overall Height 86cm Weight 9.2 k.g. Karma KM 2500 Small Wheel Wheelchair Seat and Back AEGIS Microbe Shield Approved by the FDA, EPA, EU, etc., bonded anti-microbial barrier upholstery protects from odor, staining and deterioration from bacteria, fungus and other microorganisms. It is a shield for your health. Karma KM 2500 Small Wheel Wheelchair Extended Armrest: By simulating the natural position of arms, the extended armrest design is ergonomic and creates bigger seating space. An Ultra lightweight wheelchair (9.2 kg) with a compact design for either attendant assisted or self propelling users. The use of aircraft-grade aluminium alloy and double cross brace provide this model with outstanding strength and durability. Karma Healthcare KM-2500 Premium Wheelchair is amazingly light and compact transit wheelchair which is ideal for outings and travelers. It folds down to take up virtually no space in the boot of a car and weighs just over 9.2 kg making it easy for anyone to lift into a v

Heavy Duty Wheelchair specialy design for disabled and handicapped persons. They two types of Heavy Duty Wheelchair for handicapped and disability product like- Karma 8020 X Heavy Duty Wheelchair Karma 8520 Heavy Duty Wheelchair Karma 8020 X Heavy Duty Wheelchair Karma 8020 or Karma KM-8020 Heavy Duty Wheelchair specialy design for disabled and handicapped persons. Some features are mentioned below- Features It comes with detachable swing away footrests. The wheel chair has flip-back armrests. It comes with centre of gravity adjustment. The wheel chair has wide profile casters. Seat Size 20'' inch & 22'' inch Total Weight 17 K.G. Karma 8020 X Heavy Duty Wheelchair Item Code and Price Item Code: WCI-52 MRP: Rs 45162 Our Price: Rs 32900 Net Price: Rs 32242( Apply Coupon Code 'MSW2365' Get 2% Discount ) Karma 8520 Heavy Duty Wheelchair Karma 8520 or Karma KM-8520 Heavy Duty Wheelchair specialy design for disabled and handicapped persons. Some features are mentioned below- Features It comes with detachable swing away footrests. The wheel chair has flip-back armrests. It comes with centre of gravity adjustment. The wheel chair has wide profile casters. Seat Size 20'' inch & 22'' inch Total Weight 17 K.G. Karma 8520 Heavy Duty Wheelchair Item Code and Price Item Code: WCI-29 MRP: Rs 32085 Our Price: Rs 24063 Net Price: Rs 23582( Apply Coupon Code 'MSW2365' Get 2% Discount ) Heavy Duty Wheelchair Online Purchases: This Website is only a venue where Users may meet and interact with us for their sale and purchase transactions. The commercial / contractual terms include without limitation price, shipping costs, date, period, mode of delivery, warranties related to products and services including after sales services related to product(s) and services, etc., over which we have complete control and same may be the subject to change. The agreement between you and wheelchairindia.com is subject to the following terms and cond

Heavy Duty Wheelchair specialy design for disabled and handicapped persons. They two types of Heavy Duty Wheelchair for handicapped and disability product like- Karma 8020 X Heavy Duty Wheelchair Karma 8520 Heavy Duty Wheelchair Karma 8020 X Heavy Duty Wheelchair Karma 8020 or Karma KM-8020 Heavy Duty Wheelchair specialy design for disabled and handicapped persons. Some features are mentioned below- Features It comes with detachable swing away footrests. The wheel chair has flip-back armrests. It comes with centre of gravity adjustment. The wheel chair has wide profile casters. Seat Size 20'' inch & 22'' inch Total Weight 17 K.G. Karma 8020 X Heavy Duty Wheelchair Item Code and Price Item Code: WCI-52 MRP: Rs 45162 Our Price: Rs 32900 Net Price: Rs 32242( Apply Coupon Code 'MSW2365' Get 2% Discount ) Karma 8520 Heavy Duty Wheelchair Karma 8520 or Karma KM-8520 Heavy Duty Wheelchair specialy design for disabled and handicapped persons. Some features are mentioned below- Features It comes with detachable swing away footrests. The wheel chair has flip-back armrests. It comes with centre of gravity adjustment. The wheel chair has wide profile casters. Seat Size 20'' inch & 22'' inch Total Weight 17 K.G. Karma 8520 Heavy Duty Wheelchair Item Code and Price Item Code: WCI-29 MRP: Rs 32085 Our Price: Rs 24063 Net Price: Rs 23582( Apply Coupon Code 'MSW2365' Get 2% Discount ) Heavy Duty Wheelchair Online Purchases: This Website is only a venue where Users may meet and interact with us for their sale and purchase transactions. The commercial / contractual terms include without limitation price, shipping costs, date, period, mode of delivery, warranties related to products and services including after sales services related to product(s) and services, etc., over which we have complete control and same may be the subject to change. The agreement between you and wheelchairindia.com is subject to the following terms and cond

Karma KM-2500L Wheelchair is built with an ultra-lightweight aircraft-grade aluminum alloy frame with a standard seat width of: 16" and 18", it has a foldable frame with dual brake system and 20" flat-free rear wheels.It is Suitable for air travel or in limited space, senior care Ultra-light weight aircraft-grade aluminum alloy frame. Karma KM 2500 L Wheelchair Extended Armrest Karma KM-2500 L Wheelchair is amazingly light and compact transit wheelchair which is ideal for outings and travelers. It folds down to take up virtually no space in the boot of a car and weighs just over 11 kg making it easy for anyone to lift into a vehicle.Backrest folds-down for easy transportation Maximum user weight: 100Kg Aluminum frame Fixed armrest/fixed footrest Foldable frame via double cross bars Comfortable & durable upholstery Swing-away footplates. Key Features: Ultra-lightweight aircraft-grade aluminum alloy frame Standard seat width: 16" and 18" Foldable frame with dual brake system 20" flat-free rear wheels Attendant cable brake Detachable and washable cushion Maximum user weight: 100Kg One Year Warranty Karma Travel Wheelchair KM TV20 606 T-6 aircraft-grade aluminum-alloy frame provides incredible strength. Easy-to-fold in three seconds. Type: Travel Weight: 8.9kg Seat width: 39.5cm Tyre: PU front casters and rear wheels Capacity: 100kg Folded size: (L/W/H): 610mm x 350mm x710mm

Insights Care is honored to present "The 20 Leading Healthcare Solution Providers 2017" which are adapting novel technologies to meet and exceed the health care standard. We have, on our cover, Validic - a cloud-based platform and the market leader in health data connectivity that provides healthcare organizations access to personal health data, gathered from FDA-listed in-home medical devices, wearables and healthcare apps. Led by company's CEO and co-founder, Drew Schiller, Validic serves as a technical partner and strategic advisor, guiding its clients through digital health data integration and innovation. At Validic, Drew leads corporate strategy, drives key initiatives and works closely with senior executives at partner organizations to stay ahead of the technology curve. He believes that digital health will reshape healthcare.

Damien Troy Matcham can certainly be termed as one of the most respected entrepreneurs in Australia and he comes along with a massive experience of more than 20 years in the health sector. He is currently managing his own firm which is indulged in providing the best in class health facilities and medical assistance to people around the country. If we look into his big journey of 20 years in the health domain.

The best seamless thong shaper that slims your waist instantly ! Look stunning with this shaper that defines your curves and it will go unnoticed with anything you wear . The best body shaper for women in the market the seamless body shaper thing style , so why would you want to wear a body shaper that tells everyone every time you wear it? The seamless body shaper Thong Shaper by Ann Michell is terrific for taming the tummy. On the outside, this may look like an ordinary shaper, but as they always say, you can never tell a book by its cover. This bodysuit thong shaper hides the tummy it has three super slimming layers that are invisibly smooth, sculpt and show off your sexy silhouette without showing that you are wearing a body shaper. Its thong back makes it perfect for even your slinkiest and sheerest outfits. Pair it with your favorite bra and its underbust design lifts and supports, enhancing your cleavage. RESULTS - Firmed and flattened midriff Visibly reduced waistline Smoother silhouette Invisible slimming Supported bust FEATURES - Three slimming layers Firm control Thong back Seamless look Cotton inner lining for comfort Adjustable straps Cotton gusset for easy bathroom use Materials: Back outer lining 80% nylon, 20% spandex. Back inner lining 100% latex. Frontal-middle lining 100% latex. Inner lining 80% nylon, 20% spandex.

Thornton & Ross is all set to expand its consumer healthcare offering by acquiring the well-established Opticrom eye-drops brand from Sanofi in the UK. Opticrom forms part of a wider transaction between Thornton & Ross' parent group, STADA, and Sanofi for eight local consumer healthcare brands across several countries, including Belgium, Germany, Hungary, Spain and the UK. The transaction will be financed with a combination of cash on balance sheet and existing facilities, and is scheduled to close in the fourth quarter of 2023, subject to customary approvals of relevant regulatory authorities. Opticrom Allergy 10ml bottle and 20 single doses for itchy, watery, red and inflamed eyes can be found behind the pharmacy counter, while Opticrom Hayfever 10ml bottle is available to purchase via self-selection to soothe and relieve eye symptoms of hayfever. These non-prescription medicines contain 20 mg/1ml sodium cromoglicate (2.0% w/v) and offer relief within 2 minutes.

Pharmacists are a vital member of the multidisciplinary team (MDT) supporting older people to manage their pain. The pharmacist is uniquely positioned to holistically review drug interactions and potential risks associated with each patient's medication and has the expertise to suggest alternative treatment options to reduce the risks associated with polypharmacy or unwanted side effects caused by other medications. Chronic pain The International Association for the Study of Pain defines pain as an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage. Although universally experienced by everyone, the perception of pain is a deeply personal experience influenced by biological, psychological, and social factors, and constitutes an essential behavioural feedback mechanism aimed at protecting us from harm. Pain may be perceived as either acute or chronic. Chronic pain, defined as pain that persists longer than the normal healing time, constitutes a substantial healthcare burden, affecting approximately 20 per cent of people worldwide and accounts for 15-20 per cent of physician consultations. Chronic pain is often associated with disrupted mood and sleep, substance misuse and other chronic conditions. Additionally, comorbidities of chronic pain may also lead to complex medication regimens that increase the risks of adverse drug interactions and unwanted side effects.

Health secretary Sajid Javid visited Medicine Chest Pharmacy in London on Friday (January 28) and thanked pharmacy teams across England for delivering well over 20 million Covid-19 jabs. According to the latest research conducted by the National Pharmacy Association (NPA) and PharmData, independent community pharmacies were the biggest deliverers of Covid-19 vaccines during January 2021 to September 2021 as compared to corporate-run pharmacy sites. As of January 2022, pharmacies across the whole sector had delivered 22 million Covid jabs, with the majority of them being independents of whom most are NPA members. In a video message released after the visit, Javid said: "Today I am here at Medicine Chest pharmacy in London to thank them, all pharmacies, the NHS, for the fantastic job they have done particularly over the last few months to get our country boosted. It's because of this phenomenal success that today we are able to return to Plan A as we see Omicron in retreat and we learn to live with Covid."

An oral drug combination by Novartis showed promise in treating a subgroup of patients suffering from a common childhood brain cancer in a trial. In the mid-stage trial, 47 per cent of the patients that were given the two drugs Tafinlar and Mekinist saw their tumours shrink, far above a rate of 11 per cent in a comparative group of participants on standard chemotherapy, the drugmaker said on Monday, June 6. The participants, aged one to 17 years, were suffering from low-grade gliomas (LGG), the most common childhood brain cancer. The trial only included those who were found to have a mutation known as BRAF V600, a genetic contributor in about 15 per cent to 20 per cent of paediatric LGG cases. Among further results of the trial with 110 participants, the median time without disease progression was 20.1 months for those given the Novartis drug combo, compared to 7.4 months on chemotherapy. The new oral treatment candidate also caused less severe side effects than burdensome chemotherapy.