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The Janssen Pharmaceutical Companies of Johnson & Johnson announced that the Scottish Medicines Consortium (SMC) has approved Ponvory (ponesimod) for treating adults with relapsing-remitting multiple sclerosis (RRMS) within NHS Scotland. Ponesimod offers an additional treatment choice for the ailment, which affects over 15,000 people in Scotland. Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the central nervous system in which immune cells attack myelin, causing inflammation. The common symptoms of this disease include fatigue, balance and walking problems, numbness or tingling, dizziness and vertigo. Amanda Cunnington, director of Health Economics, Market Access, Reimbursement, Government Affairs & Patient Engagement, Janssen-Cilag Limited said: "This decision further supports our commitment to ensuring patients living with this condition have access to new treatment options to help address some of the life-long and life-limiting symptoms of MS.

NHS cancer check has set a new record, despite pressures on hospitals due to Covid-19, the number of people being treated for the cancer remained higher than before the pandemic, revealed NHS. Over the last 12 months almost three million people were referred for cancer checks which is up by over a tenth on the 2.4 million people referred before the pandemic. "Even at the peak of the Omicron wave, referrals for suspected cancer were at 116 per cent of pre-pandemic levels with around 11,000 people getting checked every day over the last year," said NHS. In order to meet increasing demand for cancer checks, NHS services across the country are expanding their diagnostic capabilities through one stop shops for tests, mobile clinics and cancer symptom hotlines, ensuring people are diagnosed and treated as early as possible to give them a much better chance of beating the disease. More than 30,000 people every month are being invited for lung cancer checks through NHS mobile trucks visiting at risk communities across the country, as part of the biggest programme to improve early lung cancer diagnosis in health service history.

Insomnia is a condition that prevents a person from getting peaceful and sound sleep for hours. It is a symptom that occurs due to various symptoms and causes. This sleep disorder affects people in different ways. If you suffer from insomnia, you may not be able to fall asleep or stay asleep. Cognitive behavioral therapy or CBT is a type of psychotherapy used to treat insomnia, anxiety disorders, depression, eating disorders, marital disorders, and quality of life. Cognitive-behavioral therapy focuses on changing individuals' negative thoughts because thoughts can primarily contribute to the construction of anxiety, depression, and emotional difficulties. Many people typically need at least 3-4 hours of sleep a night, but the average sleep time is 6-9 hours. This means that sleep duration and sleep cycles vary from person to person. The most important thing is to get enough sleep, no matter how long it takes. The best remedy to treat the symptoms of this disorder is to use OTC Zolpidem 5mg Tablets Online.

Chronic pain is a type of pain that usually lasts for weeks to months. This pain can come and go, and it can be anywhere in the body. Chronic pain can lead to anxiety, depression, and insomnia. Chronic pain is quite different from acute pain and there are some differences between the two types. People usually experience severe pain, when it is injured by a broken bone or a cut on the skin. This pain does not last long. Pain is not something that can be ignored. If it grows, it should be fixed. As fear and pain persist, one begins to think negatively. Long-term negative thoughts begin to form in his mind, a process called fear conditioning. This factor causes an increase in blood pressure and anxiety disorders. Chronic pain is difficult to treat, and results in increased pain, fear, and negative thoughts. Extreme levels of fear lead to more pain, and the cycle of pain threats can be difficult to break. One of the best pills used to treat body pain symptoms is Hydrocodone 325mg, which you can easily buy from any trusted online pharmacy, such as Pharma Health Online.

Silver Diamine Fluoride 38% Caries Protecting Solution Caries Remover fagmin COMPOSITION : Silver diamine fluoride contains approximately 24-28 % (weight/volume) silver and 5-6 % (weight/volume) Research on the use of Silver Diamine Fluoride says exposure to one drop of SDF orally would result in less fluoride ion content than is present in a 0.25 mL topical treatment of fluoride varnish. The exact amount of silver and fluoride present in one drop of SDF is determined by the specific gravity of the liquid and the dropper used. The main disadvantage of SDF is its esthetic result (i.e., permanently blackens enamel and dentinal caries lesions and creates a temporary henna-appearing tattoo if allowed to come in contact with skin). Skin pigmentation is temporary since the silver does not penetrate the dermis Practical Applications in the following cases : High caries-risk patients with anterior or posterior active cavitated lesions havioral or medical management challenges Patients with multiple cavitated caries lesions that may not all be treated in one visit Difficult to treat cavitated dental caries lesions Patients without access to or with difficulty accessing dental care Active cavitated caries lesions with no clinical signs of pulp involvement.

Supplements became hugely popular in the last decade to treat deficiencies and boost various body functions. People who work out use supplements to promote muscle growth and gain energy during exercise. If you are suffering from hormone or vitamin deficiency, you can get off-the-shelf supplements to get your daily intake of these vitamins. However, there have been cases where some people became too reliant on supplements and started taking more than the required dose. Although most of them are made from natural ingredients, it's not particularly safe to use any supplement before understanding what it is and if you actually need it. Here are a few things you need to know before taking supplements or pill products. SUPPLEMENTS DON'T REPLACE A HEALTHY LIFESTYLE Taking supplements every day doesn't mean you are leading a healthy lifestyle. Supplements support this lifestyle but they're not the basis of being healthy. If someone doesn't exercise, eats junk food all the time, and smokes heavily, taking supplements will not make them live or feel better. It all starts with leading a healthy lifestyle, and if you want to boost body function or treat a deficiency, then supplements will have the desired effect. EVERYONE IS DIFFERENT There is no magic solution that works for everyone on the planet. What worked for your friend may not necessarily work for you. Popping a pill or drinking a supplement shake won't improve your performance unless you are taking the right supplement for what you need to be targeted. For instance, vitamin B12 comes from meat, fish, and dairy foods, so vegans should look for a supplement that will provide them with this vitamin.

The new data from NHS England has revealed that more than 100,000 patients were treated for minor illness by their high street pharmacist in just one month. According to new NHS figures, in June, 118,123 people with minor illnesses such as a sore throat or constipation, or those in need of medicine urgently, received a same-day consultation with their local pharmacist after calling NHS 111 or their GP practice - an increase of more than four-fifths (83%) on the number in the same month last year (64,512). The data comes alongside expanded roles for community pharmacies ahead of winter, announced at the NHS England board meeting today. "From this week, NHS 111 online can directly refer people to their high street pharmacist for a same-day consultation, rather than patients needing to call the phone line," said NHS England. Amanda Pritchard, NHS chief executive, said: "Our local pharmacies ensure hundreds of thousands of people every week get the support and medication they need and today's figures show that in just one month, over 100,000 patients have also had consultations with their local pharmacist for minor illnesses - this means patients are getting the care they need quickly but also in a convenient way that can fit in with their busy lives.

A University College London team of researchers has developed an artificial intelligence (AI) programme that can identify minute brain anomalies that lead to epileptic seizures. The algorithm, used in the Multicentre Epilepsy Lesion Detection project (MELD) and which reports locations of abnormalities in cases of drug-resistant focal cortical dysplasia (FCD) - a major cause of epilepsy - was developed by a multinational team who used more than 1,000 patient MRI scans from 22 international epilepsy centres. Brain regions known as FCDs have evolved improperly and frequently lead to drug-resistant epilepsy. Surgery is usually used to treat it, however, finding the lesions on an MRI is a constant problem for doctors because MRI scans for FCDs can appear normal. The scientists employed about 300,000 places throughout the brain to quantify cortical properties from the MRI scans, such as how thick or folded the cortex/brain surface was.

Dental surgery refers to the specialized field of dentistry that involves surgical interventions to diagnose, treat, or prevent oral health problems. Dental surgery plays a vital role in maintaining oral health and treating a variety of dental conditions

British drugmaker AstraZeneca said on Thursday (June 1) it would stop developing its drug brazikumab to treat inflammatory bowel diseases, including Crohn's disease and ulcerative colitis. The company said the discontinuation was due to a delay in the drug's development timeline, affected by global events and "the context of a competitive landscape". AstraZeneca regained the rights to brazikumab from Allergan in 2020 following U.S. drugmaker AbbVie's $63 billion tie-up with Allergan. AbbVie will stop funding the drug's development, AstraZeneca said. AbbVie's Skyrizi also treats Crohn's disease.

Amgen Inc sued Novartis AG's Sandoz in a federal court in the United States on Monday (May 1), accusing Sandoz's proposed versions of its multibillion-dollar bone-strengthening drugs Prolia and Xgeva of infringing several patents. Amgen asked the New Jersey court to block Sandoz's biosimilars of the drugs until its patents expire. One of the patents named in the complaint does not expire until 2037. Sandoz declined to comment on the lawsuit on Tuesday. Novartis, which is also named in the complaint, is preparing to spin Sandoz off into a standalone company later this year. Amgen's Prolia is used to treat osteoporosis. Xgeva, with the same active ingredient denosumab, treats bone cancer and prevents fractures in bone-cancer patients.

AstraZeneca said on Monday (June 27) two of its existing therapies were recommended for treating patients with some forms of high-risk breast cancers in the European Union, in a boost to the company's oncology portfolio. Lynparza, a cancer drug developed jointly with U.S.-based Merck, was backed for standalone use or in combination with endocrine therapy in adults with a form of genetically mutated early-stage breast cancer. The drug, which has received a similar recommendation in the United States in March, is a key asset for AstraZeneca. It was recommended in patients with low-to-normal levels of a protein known as HER2 that is the target of several new therapies. Enhertu - developed jointly with Japan's Daiichi Sankyo (4568.T) - was the other drug that was endorsed by the European Medicines Agency for treating an aggressive form of breast cancer characterised by a high rate of HER2.

Bipolar disorder can be a very challenging mental illness to deal with. It is characterized by severe mood swings, from manic highs to depressive lows. Many people with bipolar disorder struggle to live normal, productive lives. However, there are various treatments available that can help manage the symptoms of this condition and improve quality of life. In this article, we will discuss the different treatments for bipolar disorder and how to properly deal with the symptoms. MEDICATIONS One of the most common treatments for bipolar disorder is medication. There are a variety of different medications that can be used to treat the symptoms of bipolar disorder. The type of medication that is prescribed will depend on the individual's specific situation. Some common medications that are used to treat bipolar disorder include mood stabilizers, antipsychotics, and antidepressants. However, it is important to note that these are serious medications and should only be taken under the supervision of a qualified mental health professional. So, never attempt to take these medications on your own.

The UK Health Security Agency (UKHSA) has raised alarm over rising cases of extensively antibiotic-resistant Shigella infections, mainly in gay, bisexual, and other men who have physical relationship with men (GBMSM). There has been a 53 per cent increase in cases since the beginning of 2023, mostly driven by a cluster of antibiotic resistant strain called Shigella sonnei, with 97 cases reported this year until November, compared to just four cases last year. According to UKHSA, Shigella sonnei infections are difficult to treat as the strain does not respond to the antibiotics typically used to treat the bacteria. While it has been found across England, cases are concentrated in London (45), the North West (21) and South East (12). Shigella is an infectious gut infection that can cause symptoms like diarrhoea (sometimes mixed with blood), stomach cramps and fever, which are commonly mistaken for food poisoning.

The Pharmacists' Defence Association has helped its members to secure around £196,000 last year from employers who treated pharmacists badly or breached their rights in some way. The association strives to help members to resolve workplace disputes quickly, locally, and amicably, however some cases need escalation into the legal system, it said. It helps pharmacists to understand and exercise their rights in case unfair treatment occurs to them. Though no employee expects to be treated badly, this is the reality for some pharmacists, the PDA stated.

The Medicines and Healthcare products Regulatory Agency (MHRA) has launched a public consultation on plans to reclassify a locally-applied hormone replacement therapy product to treat the cause and relieve the symptoms of vaginal atrophy. The MHRA is proposing that Gina 10 microgram vaginal tablets, containing oestradiol, be made available over the counter as a "self care" product, under the supervision of a pharmacist. The Commission on Human Medicines too has advised that the application by Novo Nordisk, which is used to treat vaginal dryness, caused by oestrogen deficiency in postmenopausal women, can be made available as a pharmacy (P) medicine. The MHRA has been asking GPs, pharmacists and members of the public for their opinions on whether the tablets can be made available to women aged 50 and over who have not had a period for at least a year. If the reclassification goes ahead, pharmacists will be given training materials and a checklist to help them supply the medicine safely.

The new deal struck by the NHS will enable provision of a life-saving treatment for babies and young children who suffer with a rare and fatal genetic disease, metachromatic leukodystrophy (MLD). The revolutionary gene therapy treatment, known by its brand name Libmeldy, is used to treat MLD, which causes severe damage to the child's nervous system and organs, leading to a life expectancy of just five to eight years. Having a reported list price of more than £2.8 million, it is the most expensive drug in the world, but can now be offered to young patients on the NHS in England after the health service negotiated a significant confidential discount. the drug works by removing the patient's stem cells and replacing the faulty gene that causes MLD before then re-injecting the treated cells into the patient. The most common form of MLD usually develops in babies younger than 30 months and can cause loss of sight, speech and hearing, as well as difficulty moving, brain impairment, seizures, and eventually death.

A group of drugs commonly used to treat erectile dysfunction may be able to boost the effect of chemotherapy in oesophageal cancer, according to new research funded by Cancer Research UK and the Medical Research Council. The research, published on Tuesday (June 22) in Cell Reports Medicine, found that the drugs, known as PDE5 inhibitors can reverse chemotherapy resistance by targeting cells called cancer-associated fibroblasts (CAFs) residing in the area surrounding the tumour. Although this is early discovery research, PDE5 inhibitors combined with chemotherapy, may be able to shrink some oesophageal tumours more than chemotherapy could alone, tackling chemotherapy resistance, which is one of the major challenges in treating oesophageal cancer. Oesophageal cancer affects the food pipe that connects the mouth to the stomach, and while it is a relatively rare cancer, the UK has one of the higher rates in the world, with 9,300 new oesophageal cancer cases in the UK every year. Resistance to chemotherapy in oesophageal cancer is influenced by the tumour microenvironment, the area that sounds the tumour. This is made up of molecules, blood vessels, and cells such as cancer associated fibroblasts (CAFs), which are important for tumour growth. It feeds the tumour and can act as a protective cloak, preventing treatments like chemotherapy from having an effect.

Some herbs have diuretic effects and may help with sodium and water retention. Instances include: Dandelion "Ginger" Parsley Hawthorn Juniper Natural diuretics could help lessen fluid retention by making you urinate more. But more scientific evidence can prove that these herbs have diuretic impacts, so you may not find them compelling. Ginger is a spice that has a long history of use as a medicinal herb. It's been used to treat everything from colds to diarrhea, but one of the most common uses for ginger is that it acts as a diuretic to get rid of water retention (swelling) in the body. While there's no single cause for swelling or bloating, it can happen because of a variety of factors, including being overweight or gaining weight rapidly due to muscle building or pregnancy. However, ginger isn't just used as an herbal remedy: its active ingredient, shogaol, also exists naturally in other foods like broccoli and carrots! What is ginger? The ginger plant is the underground, fleshy part of the plant that forms a rhizome. It's a perennial herbaceous flowering plant in the Zingiberaceae family. It looks like a small palm tree with reddish-brown stems. Its flowers are white and fragrant with five petals and look like gingerbread cookies! The plant originated in Southern China but now grows in tropical regions all over the world, including India, Japan, and Jamaica. Ginger is used for cooking, medicine, and perfume making because of its intense flavor (which comes from an oil called gingerol). How are diuretic herbs good for you? A diuretic is a substance that promotes the production of urine. Diuretics can treat high blood pressure, heart failure, and kidney problems. They are also sometimes prescribed as a weight-loss aid to help the body eliminate excess water weight associated with bloating or edema (swelling). As you can see from its many uses and benefits, having a diuretic handy when you're feeling bloated is always a good idea. How can you make

Ginger for Weight Loss Ginger is a flavorsome and natural food that may help you supervise weight. Eating ginger fosters a feeling of fullness, an effect scientists call "satiety." Researchers at Columbia University in New York found that when bulky men drank a hot ginger drink, they had lowered feelings of appetite. Hunger can push us toward the consumption of foodstuffs. In many cases, we let our feelings of hunger evolve firmly, causing us to eat high-calorie edibles rich in sugar and fat, such as processed foods, which are well-documented to boost obesity. According to Research, ginger: Stimulates feelings of fullness Improves blood sugar regulation Decreases the amount of fat the gut absorbs Reduces gut inflammation Boosts the process of thermogenesis Ease digestion by stimulating digestive enzymes Help to Reduce Gas, Bloating, and Nausea Improve the Health of Your Gut How Does it Work? Ginger is most well-known for its ability to ease your stomach, especially when floundering with nausea or bloating issues. In your belly, ginger is doing much better in facilitating weight management and improving your health. The gut microbiota is one of the most comprehensive research areas in obesity. Researchers know that tiny microbes in your gut greatly affect your body weight. Collectively, these little microbes are called gut microbiota. The types of foods consumed impact the gut microbiota. Ginger is one of the most widely used spices and has a healthy effect on gut microbes. Ginger emerges to lower gut inflammation and helps the body be better responsive to insulin, enabling improved blood sugar control and reduced weight gain. A 2020 research study published in the European Journal of Nutrition noted that ginger changed the gut microbiota in rats in a manner that helped reduce obesity. Stimulates Stomach Movement to Promote the Elimination of Waste Products Ginger root is a natural digestive aid that can help promote the elimination of waste products in your b