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The NHS has signed the first-of-its-kind subscription deal for two antimicrobial drugs - cefiderocol and ceftazidime-avibactam, manufactured by Shionogi and Pfizer respectively - that will help around 1700 patients per year with severe bacterial infections. Under this deal, pharmaceutical firms will receive a fixed yearly fee - capped at a level that represents value to taxpayers - in order to incentivise funding for innovation that can generate a pipeline of new antibiotics for NHS patients. NHS said the deal will help patients with serious infections that have evolved so much that antibiotics and other current treatments are no longer effective can be given a potentially life-saving alternative. The drugs will provide a lifeline to patients with life-threatening infections like sepsis, hospital or ventilator pneumonia and blood stream infection. Announcing the deal at NHS ConfedExpo, NHS Chief Executive Amanda Pritchard called the revolutionary subscription deal a game-changer and the latest NHS success in using its commercial power to benefit NHS patients in line with the NHS Long Term Plan. "Superbug-busting drugs on the NHS will save lives and strike a blow in the global battle against antimicrobial resistance," Pritchard said.

A pharmacist in a leading independent pharmacy chain shares his myth-busting Ramadan advice on managing health and the use of medication while fasting. While the holy month means total fasting in terms of oral consumption, it's still ok, says Ifti Khan, superintendent pharmacist at Well Pharmacy, to have vaccinations and blood tests and to use eye drops or other medical items that are not ingested through the mouth. It's also important for people to keep taking their prescribed medication over the Ramadan period. Anyone who is concerned should speak to their pharmacist about whether they can take their medicine at different times, as stopping it could have serious consequences. Mr Khan, who will be observing Ramadan himself, said: "Confusion can sometimes arise when it comes to medication and managing health conditions whilst fasting", adding it is important for patients to keep managing health during Ramadan. Having injections or vaccinations is fine, as are blood tests, using eye or ear drops, and using anything that patients don't consume orally - so nicotine and other transdermal patches, pessaries and dialysis, for example. It's also ok to eat and drink as a result of a condition which causes forgetfulness.

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The NHS has launched plans to expand pioneering subscription-style drug contracts to develop lifesaving antibiotics of the future. It is building on its world-first pilot to incentivise the pharmaceutical industry to develop new antibiotics that could be offered to NHS patients when they need them the most. The consultation has launched almost a year to the day that contracts for two superbug-busting drugs were rolled out as part of a world-first pilot. Cefiderocol and ceftazidime-avibactam, new antibiotics manufactured by Shionogi and Pfizer respectively, were awarded world-first subscription contracts which provided the companies with a fixed annual fee based primarily on the availability of the drugs and their value to the NHS, as opposed to the volumes used. By breaking the link between the payments companies receive and the number of their antibiotics prescribed, the NHS is removing any incentive to overuse antibiotics, decreasing the risk of life-threatening infections, such as sepsis and pneumonia, becoming resistant to treatment.

The Company Chemists Association (CCA) has published a report highlighting the key findings of a roundtable it hosted earlier this month. The CCA convened the virtual roundtable to examine the best practice undertaken by a cross-section of LPCs to promote the delivery of the Pharmacy First service. Key recommendations for how LPCs can help support pharmacy contractors to deliver the Pharmacy First service include: Direct engagement with NHS regions who can supply funding to drive Pharmacy First engagement and promotional activity. Engagement with a variety of staff within GP surgeries, ranging from reception staff to GP partners, to drive referrals, as well as build understanding and awareness of the benefits to General Practice. Harnessing data to inform GP surgeries how they are performing locally Using data to ensure pharmacies close any open referrals promptly. Using multiple channels to promote the service, including the sharing of best practice, myth busting, use of data and creating tools which can be readily used by pharmacies and GPs. Encouraging pharmacy staff to highlight the Pharmacy First service to customers - with specific emphasis on the provision of NHS-funded care, timely access and convenience the service provides. The CCA said the report is intended to support all LPCs and pharmacy contractors as they work together to care for patients requiring urgent NHS care in their community.

"Britain will always be your home," said Wes Streeting, Secretary of State for Health and Social Care, in a video message to NHS and care staff in response to recent violence targeting healthcare workers from ethnic minority backgrounds. In the video posted on X, Streeting said: "I have been appalled by recent news reports of violence over the last week directed towards Filipino nurses in Sunderland, GPS closing early out of fear of riots and the torching of a Nigerian care worker's car. "These people are there for our country when we need them. They look after us at our most vulnerable and bust a gut to keep us well. Their attackers bring shame on our nation and our flag." Streeting underscored that the government will not tolerate NHS or social care staff being subjected to intimidation, harassment or racist abuse.

Three Wembley drug gang members have been sentenced for their involvement in a large-scale importation and distribution of unregulated pharmaceutical drugs into the UK from India. Salman Ansari, 33, and his wife Juhi Ansari, 32, of Central Road, Wembley, were among the defendants who were found guilty after a six- week trial and sentenced on 25 October at Southwark Crown Court. Salman and another gang member Waqas Saleem, 33, of Sylvia Gardens, Wembley, were found guilty of 12 counts of possession with intent to supply drugs (Class A, B and C), one count of conspiracy to supply Class C and one count of money laundering. While Salman received a six-year prison sentence, Waqas Saleem was sentenced to two and a half years. Juhi was found guilty of one count of money laundering and received a suspended sentence, requiring her to complete 100 hours unpaid work and 25 days rehab. During the operation, the City of London Police seized over 730kg of drugs, including opioids and benzodiazepines, which are commonly misused for their sedation effect and can be fatal when combined.

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Thirteen people were arrested following raids at four drug manufacturing units in the Indian states of Gujarat and Rajasthan, resulting in the seizure of mephedrone valued at Rs 230 crore (approximately 22.30 million GBP), according to a news agency report. The Gujarat Anti-Terrorist Squad (ATS) and Narcotics Control Bureau conducted the raids jointly on Friday, prompted by a tip-off received by the ATS indicating that Ahmedabad resident Manoharlal Enani and Kuldeepsinh Rajpurohit from Rajasthan had set up mephedrone manufacturing units, PTI reported on Saturday, quoting an official. As stated in an ATS release obtained by the news agency, the raids were conducted at the units in Sirohi and Jodhpur in Rajasthan and Piplaj village in Gandhinagar and Bhaktinagar industrial area of Amreli district in Gujarat. "The ATS recovered 22.028 kilograms of mephedrone (in solid form) and 124 kilograms of liquid mephedrone, collectively valued at Rs 230 crore(approximately 22.30 million GBP). "Rajpurohit was nabbed during the raid in Gandhinagar and Enani was held from Sirohi," it said.

The National Pharmacy Association (NPA) is encouraging individuals to visit their local pharmacy for the treatment of minor ailments to avoid unnecessary days off from work, save the NHS money and improve patient care. A new NPA poll revealed that 55 per cent of workers missed at least one day of work last year due to coughs, colds, and other minor illnesses. The survey, which involved over 2,000 patients and was conducted by Research without Barriers, found that 31 per cent of respondents were absent from work for 1-6 days, 15 per cent for a week, 12 per cent for two weeks and 3 per cent for three weeks. This polling is part of the NPA's Ask Your Pharmacist Week campaign, which aims to dispel common myths around minor ailments and encourage greater use of local pharmacies for medical treatment. In England, pharmacies can now provide NHS treatments for a range of common ailments through the Pharmacy First Service, including ear infections, impetigo, shingles, sinusitis, sore throat, infected insect bites and uncomplicated urinary tract infections (UTIs). However, 36 per cent of people surveyed were unaware of the Pharmacy First service, with 20 per cent believing such ailments could only be treated by their GP.