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In a new study, men who took phosphodiesterase type 5 inhibitors (PDE5Is), such as Viagra (sildenafil; Pfizer), for treatment of erectile dysfunction, were found to be 18 per cent less likely to develop Alzheimer's compared to those who did not take the drugs.
The results of the population-based cohort study were published in Neurology on 7 February 2024.
Researchers at University of Oxford examined IQVIA Medical Research Data UK records of 269,725 men, who were diagnosed with erectile dysfunction between
January 2000 and March 2017.
None of the participants had any memory or thinking problems at the start of the study and they were followed for an average of 5.1 years.
During the study, 749 out of 1,119 participants taking erectile dysfunction drugs developed Alzheimer's disease.
Drugmaker Viatris said on Sunday (October 1) it had reached agreements to divest some of its businesses for a total of about £2.9 billion.
Viatris said its move to divest some of its businesses is part of its long-term strategy to streamline focus on three core therapeutic areas - ophthalmology,
gastroenterology and dermatology.
The company has received an offer of about $2.17 billion (£1.78 billion) for almost all of its over-the-counter drug business from France-based Cooper Consumer
Health. Viatris will retain rights for erectile dysfunction drug Viagra, nasal spray Dymista and select OTC drugs within certain markets.
Separately, the drugmaker said it has agreed to sell its women's healthcare business to Spanish pharmaceutical company Insud Pharma, while its active
pharmaceutical ingredients business in India will be sold to Iquest Enterprises. Both divestitures would result in about $1.2 billion (£987 million) in proceeds.
Pharma giant, Pfizer has announced plans to cut 500 jobs at its Sandwich site in Kent, England as part of its ongoing $3.5 billion cost-cutting drive.
The company is also planning to shut its Pharmaceutical Sciences Small Molecule (PSSM) capabilities at the site, a spokesperson of the company told FiercePharma.
However, the Sandwich site will remain open and other functions will continue with "a different size," the spokesperson added.
Currently, around 940 people are employed at the site, which is the location where Pfizer scientists first discovered Viagra.
"We are proud of our heritage of breakthrough science in the UK and we will retain a scientific presence in the U.K. including at our Discovery Park location
in Sandwich," Pfizer's spokesperson confirmed in an email to FiercePharma.
Proprietary Association of Great Britain, PAGB - which represents manufacturers of branded over-the-counter (OTC) medicines, self-care medical devices
and food supplements - on Tuesday (12 December) celebrated 40 years of reclassification of medicines.
Expanding self-care for common ailments and minor injuries will not only help ease pressure on primary care services, but also provides significant potential
savings for the NHS, the consumer healthcare association highlighted during the event.
Nurofen (ibuprofen) and Imodium (loperamide) were the first medicines to go through Medicines and Healthcare products Regulatory Agency (MHRA)'s switch process
in 1983 to make them available over the counter - OTC.
Other reclassified medicines which were once available on prescription only include Voltarol (diclofenac dimethylammonium), Canesten (clotrimazole), Nexium
(esomeprazole), Nicorette, Nicotinell and Niquitin (nicotine replacement therapies), Regaine (minoxidil), Viagra Connect (sildenafil), Cialis Together
(tadalafil) for erectile dysfunction and Gina (estradiol hemihydrate) for the treatment of postmenopausal symptoms such as vaginal dryness.
A man has been sentenced to three and a half years in prison for illegally importing and distributing unlicensed medicines from India, the Middle East,
and the Far East.
Antoine Christopher Kolias, 31, received his sentence at Southwark Crown Court on 28 June after being found guilty of criminal activities in May.
The Medicines and Healthcare products Regulatory Agency's (MHRA) Criminal Enforcement Unit (CEU) led the investigation, dubbed Operation Bentley.
Kolias was discovered to be acting both as a distributor for an established unlicensed medicines dealer and running his own illicit business.
He was involved in the sale of sildenafil citrate, the active ingredient in Viagra, as well as Class C drugs including tramadol, zopiclone, and pregabalin between
2018 and 2019, and again between 2020 and 2021.
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