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A physically active lifestyle offers numerous benefits, including better cardiovascular fitness, healthy body weight, management of chronic illnesses like diabetes and arthritis, and improved bone health and muscular fitness. However, like the cliché statement that every action attracts an adverse reaction, physical activity has its fair share of risks, including injuries. Some common body injuries while engaging in various levels of physical activity or active sports include wrist, knee, and ankle injuries. The most common injuries are bruises, strains, and sprains, and this article focuses on the latter. A sprain is an acute soft tissue injury when ligaments get torn or stretched excessively. Ligaments are tough fibrous tissues made of collagen that connect the bones and form the different joints found in human bodies. Therefore, sprains are joint injuries, with ankles taking the giant share of most sprain injuries. It's also important to note that sprains are often confused with strains. However, they're distinctly different because the former are injuries to the ligaments in a joint, while the latter are injuries to the muscles.