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Hypovase (prazosin) 500 microgram tablets, manufactured by drug major Pfizer, will remain out of stock until mid-January 2022 due to a manufacturing issue. The Department of Health and Social Care (DHSC) and NHS England and Improvement (NHSE&I) have issued a supply disruption alert for the medicine that is used to treat heart-related troubles. Pfizer, the sole supplier of prazosin 500mg tablets in the UK, is out of stock from late November 2021, and had discontinued the Hypovase® (prazosin) 1mg tablets in May 2021. Advice for healthcare professionals In the given situation, prescribers need to review all affected patients to discuss management plans. Meanwhile, alternative medicine alpha blockers remain available to support an uplift in demand.

Alliance Healthcare UK team members Nick Atkins, Swansea Service Centre Manager, and Karl Goodall, Swansea Driver Team Manager, have climbed Pen y Fan in South Wales to support the Alzheimer's Society and raise money for dementia. The pair raised over £1,500, a cause close to Nick's heart, as his mother is a dementia patient. Dementia mainly affects people aged 65 and over, with 65 per cent of the 944,000 individuals living with dementia in the UK being women. Nick and Karl, dressed as 'glamorous grannies' with wigs, tights, and dresses, completed the mountain trek in six hours, carrying an Alliance Healthcare medicines cool box weighing over 35 kg. Alzheimer's Society supports people with dementia and their carers through national care and research efforts. Alzheimer's Society Cymru is the sole UK dementia charity funding both biomedical and care research.

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Nuffield Trust and The King's Fund are seeking feedback from community pharmacy on their proposals for the future of community pharmacy and they are seeking feedback from community pharmacy stakeholders. The online survey is the latest opportunity for pharmacy owners, LPCs and others in the sector to engage with the project to develop a Vision for Community Pharmacy. Nuffield Trust and The King's Fund want to hear their views on their proposals, ahead of the publication of the final report later this year. The vision is critically important, as it will be used to develop the future strategy for the sector and lay the groundwork for the next Community Pharmacy Contractual Framework (CPCF) negotiations. The survey is asking for thoughts on key aspects of the vision and its recommendations. The vision has been developed by Nuffield Trust and The King's Fund following an extensive programme of research, interviews and meetings of the vision Steering Group, Advisory Panel, and Working Groups, all of which have contractors, LPCs and other representatives of the sector at their heart. The vision project team are looking forward to hearing views from across the sector on their proposals and what will need to happen to make them a reality.

Balmedie Pharmacy based in Aberdeenshire, Scotland has been purchased by local expanding multiple operator JMF Healthcare. Balmedie Pharmacy is a well-performing community pharmacy that dispenses an average of 5,255 items per month. It lies completely unopposed in the large Aberdeenshire village of Balmedie, which is circa eight miles north of Aberdeen City Centre. The pharmacy has been owned by Brian Arris since 2004 and was recently brought to market to allow him to pursue other pharmacy business opportunities. Following a confidential sales process with Christie & Co, JMF Healthcare to benefit from new housing developments in this area of Aberdeenshire such as 300 new homes planned in Balmedie, approved plans for up to 500 new homes in Trump Menie Estate, and 284 new homes planned in Blackdog Village. Brian Arris, previous owner of Balmedie Pharmacy, comments, "I'm sad to see the business go as the excellent staff have helped grow the pharmacy from scratch since 2004 and we've all put our hearts and souls into providing good pharmaceutical care for the village and surrounding area. I'm confident everyone is left in safe hands with John at the helm now."

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Capitalising on strong demand for its obesity therapies, Novo Nordisk's growing appetite for deals has fuelled a bet on a U.S. gene-editing company called Life Edit Therapeutics. The Danish drugmaker's collaboration with Durham, North Carolina-based Life Edit Therapeutics - owned by ElevateBio, a cell and gene therapy company in Waltham - is focused on up to seven programs for rare genetic disorders as well as cardiometabolic diseases. At the heart of the tie-up is Life Edit's technology, called base editing, which is designed to make precise changes to the human genome by tweaking one base - or letter - into a different one without affecting other letters. Single-letter mistakes, called point mutations, can give rise to genetic diseases.

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The Pharmaceutical Services Negotiating Committee (PSNC) has invited pharmacy contractors, LPCs and others in the sector to share their views on an open consultation on the "future of community pharmacy". "The consultation - which takes the form of an online survey - is the first opportunity within PSNC's vision project for individuals and organisations to share their thoughts with Nuffield Trust and The King's Fund," said PSNC. The survey is happening in addition to an extensive programme of research, interviews and initial meetings of the vision Steering Group, Advisory Panel, and Working Groups, all of which have contractors, LPCs and other representatives of the sector at their heart. The online survey, asks five questions on topics such as Future policy goals; Why previous reviews and policies may not have fully achieved their objectives; Design principles that should underpin the service offer made by community pharmacy; and Blocks and enablers for change.

More than three quarters of British people, who have suffered persistent ill health following a Covid-19 infection, have had to cut back or change the work they do, according to a survey on the impact of long Covid published on Wednesday (November 9). In the survey of 1,002 people, conducted by market research company Censuswide, some 98 per cent of long Covid sufferers said the condition had limited their ability to work, with 78 per cent needing to cut back or change their work and 19 having ceased work altogether. Long Covid, a collection of symptoms ranging from pain and heart palpitations to insomnia and brain fog, can last for many months after initial infection. Britain's most recent official labour market data showed that a record proportion of people classified as "economically inactive" - neither working nor looking for a job - were suffering from long-term sickness. In absolute terms, the number of working-age people who are long-term sick has risen by 378,000 since early 2020.

Well Pharmacy has acquired three new pharmacies taking the total number of pharmacies owned by the chain across the UK to 746. The UK's largest independent and third largest pharmacy chain has bought Pharmacy Express in Wakefield, West Yorkshire, and two Frosts Pharmacy's in Banbury, North Oxfordshire, and Marston, near Oxford. All three pharmacies will be rebranded. # Well did not disclose the amount it paid for the new acquisitions. Operations director of Well Pharmacy Louis Purchase said that the group was "excited" to expand. "We believe passionately in community pharmacy, and we want our offering to be the best experience of this in the UK. We also hope our new colleagues can keep progressing and develop their clinical skills even further by being part of Well Pharmacy." Frosts Pharmacy teams have joined Well from their pharmacies based in Ferriston, Banbury, North Oxfordshire and Marston, near Oxford. They both serve local people from the heart of their communities and offer a successful travel vaccination clinic in Marston.

Boots has welcomed job applications from LloydsPharmacy staff impacted by the news of closure of all its branches located in Sainsbury's before the end of 2023. The company is recruiting for more than 1,500 pharmacy roles nationwide. Vacancies span pharmacy roles at all levels - from Pharmacy Advisors (Dispensers) and Trainee Pharmacists to experienced Pharmacists looking to develop their careers. Sebastian James, Managing Director of Boots UK & ROI, said: "Pharmacies deliver vital healthcare in the heart of communities. News of the closure of LloydsPharmacy branches within Sainsbury's stores will no doubt have an impact on many talented pharmacists as well as their patients. "We have many roles available at Boots and welcome applications from LloydsPharmacy employees affected by the closures. Patients who are worried about their future pharmacy provision can check our store locator online to find out where their nearest Boots store is - our pharmacy team members are ready to help." There are over 2,200 Boots stores across the UK and 85% of the population live within 10 minutes of a Boots store.

Boots UK's chief pharmacist has been encouraging people to get a flu vaccination by the end of November to help protect themselves, their loved ones and the NHS this festive season. Flu cases in the UK are usually highest in the winter months, from December to March. This year, the UK has seen a rise in cases earlier than usual, and therefore Claire Nevinson, superintendent pharmacist at Boots, reminds people that it is even more important to get protected early to help reduce the risk of spreading the virus due to increased mixing at Christmas parties and family get togethers. Approximately 33 million people are eligible for the free NHS flu jab, including those over 50 years of age, pregnant women and those with medical conditions such as diabetes or heart disease. The pharmacy multiple says it offers the winter flu jab service, which is suitable for those eligible for the free NHS flu jab as well as privately, adding that it has already administered over one million flu vaccinations this season. Ms Nevinson explains: "December is a time to get together with friends and family to celebrate the month's festivities. It's a good idea to plan ahead to ensure you have your flu jab, and your COVID-19 booster vaccination if you are eligible, if you've not had them already, this the best way to protect yourself and reduce the risk of passing the viruses to others.

Well Pharmacy has announced a new partnership with RangeMe, a product discovery, sourcing and purchasing platform, as it looks to increase the diversity of products available to its customers. The independent pharmacy chain said the partnership will provide new, emerging and diverse brands increased access to its buying teams. There are already over 200,000 suppliers registered on the RangeMe platform. "We pride ourselves on being at the heart of the communities we serve and are delighted to be working with RangeMe to increase the diversity of the products we are able to offer to our customers across the UK," Reena Takhar, head of OTC & NHS buying at Well Pharmacy said. "Given the ongoing cost-of-living crisis, we're keen to do all we can to give businesses of all sizes the opportunity to connect with our buyersto allow us to offer new and interesting great value products to our customers." RangeMe helps retailers and their buying teams scale product sourcing efforts with streamlined submissions, simplified discovery tools, and the industry standard digital sell sheet.

Maintaining good dental health is important for everyone. Not only does it help you look and feel your best, but it's also essential for your overall health. Poor dental hygiene can lead to a variety of health problems, including heart disease, stroke, and even diabetes. That's why it's so important to make sure you are taking care of your teeth and gums properly. But with so many different dental treatments and products available today, how do you know which ones are right for you? Here are some helpful tips to follow: UNDERSTAND DIFFERENT DENTAL TREATMENT CATEGORIES There are three main types of dental treatments: preventive, restorative, and cosmetic. Preventive treatments include things like brushing and flossing your teeth every day, getting regular checkups, and using mouthwash. Restorative treatments involve repairing the damage that's already been done to your teeth. Cosmetic treatments improve the appearance of your teeth without necessarily fixing any damage. Which type of treatment is right for you depends on your individual needs. If you have a lot of cavities, for example, you may need restorative treatment. If you have crooked teeth, you may need cosmetic treatment. And if you just want to make sure your teeth stay healthy overall, preventive treatment may be the best option for you.

Novartis on Wednesday (February 1) predicted that core operating income would grow in a "mid single digit" percentage range in 2023 following stagnation last year, as the Swiss drugmaker prepares to spin off its Sandoz generics business. Full-year core operating income was broadly flat at $16.7 billion, it said in a statement, coming in slightly below market expectations of $16.8 billion. Adjusted for overall negative currency effects, group sales in 2022 advanced 4 per cent to $50.5 billion as gains from heart failure drug Entresto and multiple sclerosis (MS) drug Kesimpta were partly offset by competition from cheap generic copies of established MS drug Gilenya. Novartis said it was on track to spin off its generics unit Sandoz in the second half of the year as part of its effort to sharpen its focus on its patented prescription medicines. Analysts have welcomed a programme unveiled in 2022 to trim costs and cut 8,000 jobs and plans to focus on fewer therapy areas and drug technologies. But the market has been underwhelmed by prospects for medium-term growth from new drugs.

Boehringer Ingelheim UK & Ireland has appointed Vani Manja as its new Country Managing Director and Head of Human Pharma. Manja has been associated with Boehringer Ingelheim for over 11 years, in successful leadership roles in Germany, the United States and most recently as General Manager, India. Her career started as a commissioned officer in the Indian Army Ordnance Corps which preceded leadership roles at Becton Dickinson and McKinsey. She brings extensive experience of strategy, marketing, sales, business development, people management, and cultural transformation and is passionate about tackling healthcare inequalities and advancing sustainable healthcare. Commenting on her new role, Manja said: "It is with great heart that I bring the spirit of conscious leadership to my new role. I look forward to being fully present and partnering with key stakeholders in the healthcare ecosystem in our collective quest to improve health for humans and animals in the UK and Ireland."

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There are several benefits to losing weight, including higher self-esteem, better mood, improved sleep pattern, and better health in general. In addition, you can prevent various health concerns associated with obesity, such as heart problems and diabetes. There are different ways to help reduce weight, including lifestyle changes. It requires discipline, perseverance, and commitment to reach your goal and maintain it. The first step to making these changes can be challenging, but you must push yourself and keep moving forward to achieve your objective. If you are a beginner, the weight loss tips can be overwhelming, and some may be too hard to do that it could demotivate you or make you give up. So, we listed some tips for losing weight that are ideal for beginners. Set your goal Although you may want to lose weight immediately, the truth is that it will not happen overnight. Remember that it did not take one day to gain all those extra pounds, so you cannot lose them instantly. Setting your expectations straight is essential, so you won't be disappointed if you do not see an immediate result. You need consistency to be where you want to be, so make sure you have a clear objective. You can set smaller goals that you can achieve within a shorter period, then set another goal after that until you reach your ideal weight. You will feel motivated by these small wins, making you want to keep going.