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One of the long-standing medical mysteries is the diagnosis of diabetes in majority of patients suffering from high blood pressure. The reason for this had been unknown. But now, an international team of universities have made a breakthrough. The research, published online in 'Circulation Research', involved contributions from collaborating scientists in Brazil, Germany, Lithuania, and Serbia, as well as the UK and New Zealand. The important new discovery has shown that a small protein cell glucagon-like peptide-1 (GLP-1) couples the body's control of blood sugar and blood pressure. Professor Julian Paton, a senior author, and director of Manaaki Manawa, The Centre for Heart Research at the University of Auckland, said: "We've known for a long time that hypertension and diabetes are inextricably linked and have finally discovered the reason, which will now inform new treatment strategies." GLP-1 is released from the wall of the gut after eating and acts to stimulate insulin from the pancreas to control blood sugar levels. This was known but what has now been unearthed is that GLP-1 also stimulates a small sensory organ called the carotid body located in the neck.

The National Institute for Health and Care Excellence (NICE) has recommended elosulfase alfa for routine use in the NHS for the treatment of mucopolysaccharidosis type 4A (also known as MPS 4A and Morquio A syndrome). Elosulfase alfa, also called Vimizin and made by BioMarin, becomes the first disease modifying treatment recommended by NICE for routine NHS use for people with this rare, severely life-limiting condition. NICE's final draft guidance follows the collection of 'real-world' data from 69 people who received NHS-funded treatment since 2015 as part of a managed access agreement. Clinical trial evidence and data collected as part of the managed access agreement, along with expert clinical opinion, shows some long-term benefits with elosulfase alfa treatment which suggest it slows progression of MPS 4A.

If you have children, it's important to make your home kid-friendly. There are several reasons why this is important for your child's development. A kid-friendly home is a haven for your child. It's a place where they can explore and play without worrying about getting hurt. It's also a place where they can feel comfortable and secure. A kid-friendly home is also a great learning environment for your child. They can learn about new things and explore their interests in a safe and nurturing setting. Finally, a kid-friendly home is just more fun! Children are naturally curious and love to play. By making your home more inviting, you will surely enjoy watching them grow and develop. So how do you make your home more kid-friendly? Here are a few tips: Get Rid of Any and All Sharp Objects It's important to make your home safe for kids, including removing any sharp objects. This means things like knives, scissors, and other sharp tools. Even seemingly innocuous items like paper clips can harm curious little ones. So go through your house and get rid of anything that could potentially hurt a child. It's better to be safe than sorry. And if you have any doubts about whether something is safe or not, err on the side of caution and get rid of it. Better safe than sorry!

harmacists in the town of Barnoldswick in Lancashire are reportedly suffering from various problems including a lack of medicines and the movement or loss of pharmacy staff. Problems, including delays with supply of insulin, were reported at a recent Pendle Council West Craven meeting. And this week the head of one pharmacy chain, Whitworth, highlighted a range of issues faced by his teams including supply chains, costs, loss of staff and NHS reimbursement for contractors. In Barnoldswick, queues have formed inside and outside pharmacies as people attempt to get prescriptions. Some said they had to wait for days to get what they needed, had made repeat-visits to pharmacies and were unsure when medicines might arrive. They also said the number of pharmacies in the area have fallen over the years. Two town centre pharmacies, Whitworth and Well, are located opposite each other, close to a doctors' surgery. Standing in one queue outside Whitworth was Marilyn King. She said: "I have been waiting seven days to get my prescription for blood pressure and some other medicines. This week, I've come back time after time. But the staff say sorry, they have not got it in because nobody has delivered it. "I came here on Saturday, when there was a queue. But the pharmacist was not here. I came again on Tuesday and then Wednesday. Then finally, just when I reached the front of the queue, they asked me to come back in an hour…

The Pharmacist's Defence Association (PDA) has raised concerns over the adoption of Digital Clinical Excellence (DiCE) guidelines for online prescribing of GLP-1 receptor agonists for weight management in adults. This follows a clash with expert recommendations commissioned by the General Pharmaceutical Council (GPhC) as the PDA "believes the final guidance conflicts with the expert opinion underpins the GPhC's prosecution strategy towards pharmacist prescribers under investigation." In a recent statement, the PDA highlighted the discrepancy between DiCE's guidance and the expert report employed by the GPhC to prosecute pharmacist prescribers using a questionnaire-based consultation model. This conflict has prompted the PDA to withhold its endorsement of the DiCE guidance as it differs from an expert report commissioned by the GPhC. The PDA's reservations stem from the inherent risks associated with questionnaire-based prescribing.

The topic of death is often a sensitive and somber one, but it is also a reality that we must face. When someone passes away, there are many legal considerations that come into play surrounding their assets, property, and final wishes. Before delving into the specifics, you must first understand that laws and regulations surrounding death and inheritance can vary greatly depending on location. Different countries, states, and even cities may have their own unique set of laws and procedures in place. involved. That's why you need a legal overview to guide you through the process of protecting your rights in the case of death. Wrongful Death Lawsuits and Compensation In the unfortunate event of a wrongful death, where a person dies due to the negligence or misconduct of another, the bereaved family may seek compensation through legal action. Hiring a lawyer for wrongful death is the best course of action to navigate the complex legal process and ensure that your rights are protected. Wrongful death lawsuits can cover a wide range of incidents, from car accidents to medical malpractice. The compensation awarded in these cases may include funeral expenses, lost wages, and loss of companionship. Know that each case is unique and the amount of compensation awarded will depend on the deceased's income and potential earnings, their age, and the extent of their financial support to their dependents.

The Department of Health and Social Care (DHSC) has finally published its response to the 2022 consultation on hub and spoke dispensing. Considering the consultation evidence and further discussions, the government has expressed its intention to progress the proposals for enabling hub and spoke models across different legal entities as soon as possible. This will be achieved by using the enabling powers outlined in Part 2 of the Medicines and Medical Devices Act 2021 (MMDA) to amend the Medicines Act 1968 and the HMRs. Furthermore, the DHSC has decided to proceed with the implementation of the two models of hub and spoke dispensing that it consulted on. The government response to the consultation reads: "Having considered the responses, the government intend to proceed to implement the necessary changes to medicines legislation to remove the current restrictions that prevent the hub and spoke dispensing models from operating across different legal entities found in section 10 of the Medicines Act 1968.

The British Medical Association (BMA) on Wednesday announced that 33,869 junior doctors have voted in favour of extending the industrial action and the use of action short of strike (ASOS). With a turnout of 62 per cent, their demand stems from the ongoing campaign for complete pay restoration. The new mandate will last till September 19, starting on 3 April. The BMA junior doctors committee co-chairs, Dr Robert Laurenson and Dr Vivek Trivedi, expressed frustration at the year-long strike action, highlighting the government's avoidance tactics to tackle soaring waiting lists, access to GPs and staff shortages. "The government should see the urgency of the situation. Rather than waste time dragging out talks, they can come forward with a credible offer on pay right now. " "Instead, they could be celebrating a revitalised and reinvigorated junior doctor workforce, one that feels that their value has started to be restored. That would be an achievement worth celebrating for everyone and begin to finally turn the tide on the deteriorating workforce crisis," they said.

Patients suffering from chronic and episodic migraine attacks are set to benefit from a groundbreaking recommendation by the National Institute for Health and Care Excellence (NICE) regarding a new medication. The atogepant, a first-of-its-kind preventive drug for migraine, offers hope for those grappling with this debilitating condition and can be taken orally. Published as part of the final guidance draft, NICE has greenlit the atogepant, also known as Aquipta and manufactured by AbbVie, as an option for preventing both chronic and episodic migraines in adults. Specifically, this recommendation is for individuals who have experienced at least four migraine days per month and have failed to find relief with at least three previous preventive treatments. With approximately 4.5 million people in the UK affected by various forms of migraine, this new recommendation marks a significant advancement in migraine management as the condition significantly impacts patients' day-to-day activities as well as places a heavy burden on the NHS and the wider economy.

The Department of Health and Social Care (DHSC) has redetermined the December 2023 concessionary prices for four medicines following requests made by Community Pharmacy England (CPE) on behalf of community pharmacy owners. For Ezetimibe 10mg tablets (pack size 28), the price has been fixed at £17.78, up from £9.44. Other drugs included in the list are Aripiprazole 5mg (£8.52), Digoxin 125microgram (£3.70) and Digoxin 250micrgram (£3.70) tablets. Contractors would be reimbursed at the new prices only for prescriptions submitted for payment for the dispensing month of December 2023. CPE said they are still working with DHSC to agree price concessions for January. Check the final the December 2023 price concessionary here. Additionally, DHSC on Friday confirmed that there's now sufficient stock of Clarithromycin 125mg/5ml oral suspension to meet normal demand, and the Serious Shortage Protocol (SSP), SSP053 for the antibiotic expires on 12 January 2024.

The final report of the Infected Blood Inquiry has been published today, bringing to light a devastating chapter in the history of the UK's healthcare system. The inquiry, which was launched by former Prime Minister Theresa May in 2017, examined how contaminated blood products infected over 30,000 NHS patients with deadly viruses, including HIV and Hepatitis C, between the 1970s and 1990s. Following the publication of the report, Prime Minister Rishi Sunak issued a formal apology on behalf of successive governments, acknowledging the state's significant failings. He stated that he finds it "impossible to comprehend" how victims felt when injected with deadly diseases through no fault of their own.

5 Things to Know about Medicare Drug Coverage Plans. CMS released rates for 2022 for Medicare Advantage Coverage plans. They released these rates prior to the period so that Medicare plans to review them for their final bids.

Here we bring some exciting news for McDonald's lovers in North India! The McDonald's connoisseurs have faced a lot of disappointment in recent times when all the outlets were shut down. But now no more disappointment! We got some silver lining with a pleasant twiston the dark clouds. McDonald's islaunchingMcCafé in Delhi, to add to the delight of 'Mc D fans'!

Medical practices can amplify their MIPS performance via consulting and submitting data through MIPS Qualified registries.

Medical practices can amplify their MIPS 2020performance via consulting and submitting data through MIPS Qualified registries.

The Department of Health and Social Care (DHSC) has revised concession prices for four products and confirmed three further price concessions for May 2024. This announcement comes in response to representations made by Community Pharmacy England (CPE) on behalf of community pharmacy owners Concession prices have been redetermined for Ezetimibe 10mg tablets, Quetiapine 100mg tablets, Quetiapine 150mg tablets and Quetiapine 200mg tablets. Here are the newly granted concessions: Nicorandil 10mg tablets (60 tablets): £5.05 Nicorandil 20mg tablets (60 tablets): £9.30 Pregabalin 75mg capsules (56 capsules): £1.54 The revised prices will be applicable to prescriptions submitted for payment during the dispensing month of May 2024, and do not apply to June 2024 prescriptions, the CPE noted.