The widely-held concept that levels of "good" cholesterol in the blood can indicate heart disease risk is not equally true for Blacks and whites, and the measure
itself may be of less value than previously thought, according to a U.S. study published on Monday (November 21).
Various types of cholesterol are thought to have either healthy or unhealthy effects.
Low levels of so-called "good" high-density lipoprotein (HDL) cholesterol were linked with higher odds for developing cardiac problems in the long-term study - but
only in white participants, the study published in the Journal of the American College of Cardiology found.
In contradiction to what has generally been assumed, low HDL levels did not confer any higher risk of heart disease in Black people, researchers said. Among white
people, however, those with HDL levels below 40 milligrams per deciliter had a 22% higher risk for coronary heart disease compared with those whose HDL levels were
higher.
High HDL levels (above 60 mg/dL), which are thought to be protective, were not linked with lower coronary heart disease risks in either race, researchers found.
Recipes To Lower Cholesterol -- Cholesterol what is known as for most people will be flashed in her mind that something bad for your body. Cholesterol is a
It is essential for your health to understand high cholesterol symptoms and tips to manage. It becomes more vital when you are above 40. First of all, let's try to understand what is Cholesterol? It is a fat-like substance that is produced by the liver naturally. It has many functions in our body like producing specific hormones, new cell membranes, and Vitamin D.
The National Institute for Health and Care Excellence (NICE) has recommended icosapent ethyl also called Vazkepa manufactured by Amarin for adults who have cardiovascular disease with controlled LDL-C levels taking a statin.
It's final draft guidance is expected to be available on the July 20.
Nearly half a million people are expected to benefit from the first licensed treatment shown to reduce the risk of heart attacks and strokes in people with
controlled low-density lipoprotein cholesterol (LDL-C - sometimes called "bad" cholesterol) who are taking a statin and who have raised levels of triglycerides.
NICE said: "Clinical trial evidence suggests that for people with raised triglycerides who have LDL-C levels controlled by statins, and who have cardiovascular disease, icosapent ethyl reduces their risk of cardiovascular events by over a quarter compared with placebo.
Helen Knight, interim director of medicines evaluation at NICE, said: "Icosapent ethyl is the first licensed treatment of its kind for people who are at risk of heart attacks and strokes despite well controlled LDL cholesterol because they have raised blood fats. And although lifestyle changes, including diet and exercise, can help to reduce their risk, these may not work for everyone.
Esperion Therapeutics' non-statin therapy "bempedoic acid" has shown modest results in reducing the risk of major cardiovascular events in statin-intolerant
patients in the cholesterol lowering via bempedoic acid, an ACL-inhibiting regimen (CLEAR Outcomes) trial, revealed GlobalData, a leading data and analytics company.
As a result, there is substantial room for improvement in this space as a potential approval is expected in Australia in near-term based on these results, said
GlobalData.
According to GlobalData's Pharmaceutical Intelligence Center, the total number of diagnosed prevalent cases of dyslipidemia in Australia is expected to increase at
a compound annual growth rate of approximately 1.2% from 5.2 million in 2022 to 5.4 million in 2025.
Neha Myneni, Pharma Analyst at GlobalData, comments: "Bempedoic acid joins several statin alternatives that have shown the potential to reduce cardiac illnesses.
However, with not much significant improvement in the outcomes, there exists a clear room for improvement for non-statin therapies in this space."
Bempedoic acid is the sixth class of cholesterol-lowering drugs (other than cholesteryl-ester transfer protein isoform (CETPi) inhibitors), that has demonstrated the
potential to reduce heart attacks and strokes. Other class of therapies with similar potential currently marketed in Australia include statins, bile acid resins,
niacin, ezetimibe, and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors (alirocumab, evolocumab, and inclisiran).
Stroke is a cerebrovascular syndrome that involves the blockage and bursting of blood vessels in the brain. It shows a multifactorial pattern of inheritance. High cholesterol levels, high blood pressure, hypertension and obesity are the key causes of stroke besides inherited genes.
We offers the full range of blood tests with results available as early as 48 hours. Home-visits (mobile phlebotomy) offered for blood sample collection for both NHS and Private blood tests. Pregnancy HCG, Hepatitis B Immunity, Tuberculosis, Occupational Health, Vitamin tests, Glucose, Cholesterol, etc.
CoQ10 may also be a very important supplement to consider for those taking statin drugs to lower cholesterol. Statins are one the most commonly prescribed medications today.
Atorvastatin, a medicine to treat high blood cholesterol, is the most dispensed drug with 59 million items in England in 2022/23, revealed the NHS Business
Services Authority (NHSBSA) on Thursday (8 June).
While Apixaban (an anticoagulant) was the drug with the highest costs of £430 million. Apixaban 5mg tablets had the largest increase in cost between 2021/22 and
2022/23 in England, with an increase of £280 million.
NHSBSA's annual statistics report 'Prescription Cost Analysis-England 2022/23' published also has revealed an eight per cent rise in the prescription items that
were dispensed in the community in England.
The report highlighted that in 2022/23, 1.18 billion prescription items were dispensed at a cost of £10.4 billion in the community in England, witnessing an
increase of eight per cent from £9.69 billion in 2021/22.
Whether you believe it or not, following a vegan diet can be quite eventful for your body. For instance, it can help you lose weight, get a better body
structure, and so on.
However, is that all? You can get that by following a thorough exercise plan as well, no?
Well, yes, you can. Nevertheless, following a vegan diet plan can help you out in more than a single manner. Please keep reading this article till the end to know
more about it.
WHAT IS A VEGAN DIET?
As a vegan, you can eat dairy food, including cheese and milk, without any boundaries. If you want to get a little bit of protein, you may consume eggs (boiled or
in a gravy) too. Also, yes, plants are going to be an integral part of your diet plan too.
However, you won't be able to eat meat anymore. So, no chicken, mutton, or beef for the rest of your life. Instead, you will need to focus solely on plant-based
protein.
BENEFITS OF FOLLOWING A VEGAN DIET
A plant-based diet structure can be highly beneficial for your health. For example, it can -
LOWER YOUR BLOOD PRESSURE.
Hypertension, also known as high blood pressure, can increase your risk of a heart attack. It's also known to be a close counterpart of type-2 diabetes too.
Fortunately, though, the diet you follow can make quite a massive difference here. For example, following a vegan diet can help you reduce the amount of oily food
you're taking on a daily basis.
This, in turn, can decrease the amount of cholesterol in your blood and make it easier for you to lose weight. And, the less obese you are, the lower your blood
pressure will be.
A daily medication for high blood pressure could be replaced by an injection twice a year, if Queen Mary University and Barts Health NHS Trust succeed in their trail to investigate if an injection-based drug - Zilebesiran - could inhibit the production of a protein called angiotensinogen (AGT).
Scientists are to trial a world-first drug to treat high blood pressure that can be given by injection twice a year.
Professor Sir Nilesh Samani, medical director, British Heart Foundation, said: "This exciting trial could lead to good news for the millions of people across the UK with high blood pressure, many of whom need to take daily medication to lower their risk of heart attacks and strokes.
"The study will determine whether an injection given twice a year lowers blood pressure sufficiently over a prolonged period.
"If this proves to be the case, it may provide an alternative to taking daily pills for some patients."