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NHS England has urged women to accept cervical screening invites to make it possible to eliminate the disease within the next two decades. Screening using a highly effective test helps detect human papillomavirus (HPV), which is responsible for over 99 per cent of all cervical cancers. Sadly, three in ten of those eligible for screening do not take up the potentially life-saving offer, as shown by the NHS Cervical Screening Programme, England 2022-2023 annual report. The report, published by NHSE on Thursday, showed that a total of 4.62 million women aged 25 to 64 for cervical screening was invited to book an appointment in 2022-23, and 3.43 million attended the screening.

The World Health Organization said on Sunday (May 29) that monkey pox constitutes a "moderate risk" to overall public health at global level after cases were reported in countries where the disease is not typically found. "The public health risk could become high if this virus exploits the opportunity to establish itself as a human pathogen and spreads to groups at higher risk of severe disease such as young children and immunosuppressed persons," WHO said. As of May 26, a total of 257 confirmed cases and 120 suspected cases have been reported from 23 member states that are not endemic for the virus, the health agency said in a statement. There has been no reported fatalities so far. WHO also said that the sudden appearance of monkeypox at once in several non-endemic countries suggests undetected transmission for some time and recent amplifying events. The agency added that it expects more cases to be reported as surveillance in endemic and non-endemic countries expands. Monkeypox is an infectious disease that is usually mild, and is endemic in parts of west and central Africa. It is spread by close contact, so it can be relatively easily contained through measures such as self-isolation and hygiene.

Pharmaceutical Services Negotiating Committee (PSNC) has expressed its support for alterations in the Human Medicines Regulations 2012 to enable original pack dispensing (OPD) and supply of medicines containing sodium valproate by pharmacists. PSNC's support for changes was in response to the consultation on OPD, initiated by the Department of Health and Social Care (DHSC). The consultation had proposed regulatory changes to allow pharmacists to dispense (up to 10 per cent) more or less than the prescribed quantity of a given medicine in the manufacturer's original packs. Key aims of the proposal are to "support increased patient safety by ensuring patients receive the necessary information that is included in the original manufacturer's packaging about the safe and effective use of a product," DHSC said.

The Medicines and Healthcare products Regulatory Agency (MHRA) has launched a public consultation on plans to reclassify a locally-applied hormone replacement therapy product to treat the cause and relieve the symptoms of vaginal atrophy. The MHRA is proposing that Gina 10 microgram vaginal tablets, containing oestradiol, be made available over the counter as a "self care" product, under the supervision of a pharmacist. The Commission on Human Medicines too has advised that the application by Novo Nordisk, which is used to treat vaginal dryness, caused by oestrogen deficiency in postmenopausal women, can be made available as a pharmacy (P) medicine. The MHRA has been asking GPs, pharmacists and members of the public for their opinions on whether the tablets can be made available to women aged 50 and over who have not had a period for at least a year. If the reclassification goes ahead, pharmacists will be given training materials and a checklist to help them supply the medicine safely.

The Royal Pharmaceutical Society (RPS) and Pharmacy Declares are inviting pharmacy teams from around the world to sign up and commit to taking "bold action" on climate change as mentioned in a climate change charter which was published on Monday (June 13). The charter asks pharmacy teams to commit to understanding how human health and the systems which underpin it are "reliant on the state of our natural environment" and actively explore ways to make pharmacy practice and medicine use more sustainable. It also asks to collaborate and share best practice to improve sustainability in pharmacy and healthcare; demonstrate leadership on sustainability or being a champion for sustainability at work; and assist patients to optimise their medicine use to increase both health outcomes and environmental sustainability. The individuals can also commit to a personal action on climate change of their own choosing. The Charter is being supported by a strong coalition of organisations from across pharmacy including the Centre for Postgraduate Pharmacy Education, the Clinical Pharmacy Association, College of Mental Health Pharmacy and Guild of Healthcare Pharmacists.

It is common knowledge that human happiness and well-being are dependent on good health. According to The American Lung Association (ALA) though, lung cancer is the most common cause of cancer-related death in men and women as well. Unfortunately, it seems we often overlook the importance of our lungs. We tend to forget that they are nature's natural defensive system designed to keep dirt and germs out. However, there are several crucial things you can do to lower your lung disease risk. Here are some valuable guidelines for keeping your lungs in good shape. 1. AVOID EXPOSURE TO POLLUTION 2. NO SMOKING! 3. KEEP AWAY FROM INFECTIONS 4. TAKE DEEP BREATHS 5. EXERCISE REGULARLY These are the most essential and valuable guidelines that you should follow if you want your respiratory system to be healthy. Along with proper exercise, maintaining a balanced diet, and keeping your mind in a healthy vigorous state, they should form the foundation for long and prosperous life. Let's always keep in mind the teachings of ancient Greek philosophers, like Hippocrates, who maintained the axiom "a healthy mind in a healthy body", and we'll always be on the right track.

The Medicines and Healthcare products Regulatory Agency (MHRA) has been accepted as a full member of three international work-sharing partnerships. Through these partnerships the agency said it will play vital international role in making sure medicines and medical devices are regulated safely and efficiently worldwide, Two of these, the International Medical Device Regulatory Forum (IMDRF) and the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) are focused on improving the harmonisation and convergence of medicines and medical devices regulation globally. The partnerships will also help the MHRA to share expertise with other leading organisations, support the development of regulatory guidelines and drive greater harmonisation of regulation around the world. This will help deliver timely access to innovative medical products not just in the UK but globally.

The Medicine and Healthcare Product Regulatory Agency (MHRA) has recalled all pholcodine-containing medicines from the UK pharmacy due to concerns of its potential to cause a severe allergic reaction in some people having general anaesthesia for surgery. The decision was made following the conclusion of a review of post-marketing safety data by the MHRA. The Commission on Human Medicines (CHM) has considered the evidence of an increased risk of the very rare event of anaphylaxis when exposed to neuromuscular blocking agents (NMBA) and advised that pholcodine-containing medicines should be withdrawn. MHRA has advised pharmacists to consider recommending appropriate treatment alternatives for patients who present with a new dry cough or who are currently taking pholcodine. Royal Pharmaceutical Society (RPS) President Professor Claire Anderson said: "If you are taking a cough medicine (including tablets and syrups), check the packaging, label or Patient Information Leaflet to see if pholcodine is a listed ingredient - if it is, and you have any questions, you can talk to your pharmacist who can suggest a different medicine suitable for you.

The Medicines and Healthcare products Regulatory Agency (MHRA) has advised 'no one should stop taking valproate without advice from their healthcare professional.' The latest data on the use of valproate in England revealed that in the last 6 months the number of pregnant women prescribed valproate in a 6-month period has fallen from 68 women in April to September 2018, to 17 women in October 2021 to March 2022. In light of concerns that the current regulatory requirements for safe use are not being consistently followed, the MHRA conducted a review of the available data and asked for advice from the independent Commission on Human Medicines (CHM). "The CHM has advised that no one under the age of 55 should be initiated on valproate unless two specialists independently consider and document that there is no other effective or tolerated treatment," said MHRA. "Where possible, existing patients should be switched to another treatment unless two specialists independently consider and document that there is no other effective or tolerated treatment or the risks do not apply."

Genomic sequencing allowed the world to track new coronavirus variants throughout the pandemic. Now British researchers plan to use it to better understand a host of other respiratory pathogens, from influenza to respiratory syncytial virus (RSV). The work is aimed at shedding more light on known threats and, potentially, emerging ones, the team at the Wellcome Sanger Institute, working with the UK Health Security Agency, said. The world has never had access to the kind of real-time information for these viruses that scientists obtained on SARS-CoV-2 through sequencing millions of genomes, Ewan Harrison, head of the new Respiratory Virus and Microbiome Initiative, told reporters on Monday. That includes granular detail on how they transmit as well as how they evolve in the face of the human immune response. "We hope that by expanding our ability to sequence these viruses routinely, we can build upon the work that's going on COVID, and hopefully supercharge research efforts to understand the transmission of these viruses, but also to help develop new treatments and vaccines," Harrison said.

Endocrinology is the study of hormones and glands in the human body. The endocrine system produces and secretes hormones that regulate many bodily functions, including growth and development, metabolism, and reproductive health. Endocrinologists are physicians who specialize in diagnosing and treating hormonal imbalances and disorders. There are several reasons why you might consider seeing an endocrinologist. In this article, we'll explore some of the most common reasons people seek out the expertise of an endocrinologist. YOU HAVE DIABETES If you have diabetes, it is important to consider seeing an endocrinologist. Endocrinologists specialize in managing diabetes and can help you develop a personalized treatment plan to manage your blood sugar levels. They can also help you prevent or manage complications of diabetes, such as nerve damage, kidney disease, and eye problems. An endocrinologist can work with you to develop a healthy lifestyle plan that includes diet, exercise, and medication management. They can also help you adjust your treatment plan as needed to ensure that your diabetes is well-controlled. Seeing an endocrinologist can help you achieve better health outcomes and improve your overall quality of life.

The UK government on Thursday (8 May) launched a new plan to tackle antimicrobial resistance (AMR), a global issue that makes infections difficult or impossible to treat. This is the second phase of a series of 5-year national action plans, aimed at supporting the government's 20-year vision to contain and control AMR by 2040. With the launch of this new national action plan, the UK commits to reducing its use of antimicrobials - such as antibiotics, antifungals and antivirals - in humans and animals. Additionally, it aims to strengthen surveillance of drug-resistant infections before they emerge and incentivise industry to develop the next generation of treatments. There are also plans to expand initiatives such as the world-first 'subscription model' for antimicrobials, launched in 2019 as a pilot.

In a significant leap forward in the fight against HIV, the Medicines and Healthcare products Regulatory Agency (MHRA) has given the green light to two groundbreaking formulations of cabotegravir. Apretude 30 mg film-coated tablets and Apretude 600 mg prolonged-release suspension for injection are now authorized for preventing sexually transmitted HIV-1 infection in adults and adolescents weighing at least 35kg at increased risk. This approval marks a pivotal moment in HIV (human immunodeficiency virus) prevention, offering an alternative to existing standard pre-exposure prophylaxis or PrEP treatments. HIV, a virus notorious for compromising the immune system, has long been a global health concern. Cabotegravir, a member of the integrase inhibitor group, works by blocking a key enzyme necessary for the replication of HIV-1, thereby reducing the virus's ability to spread.

The results of a national NHS staff survey, published recently, revealed that frontline healthcare workers are facing record levels of discrimination at work, with 58,000 respondents reporting that they experienced "unacceptable" levels of unwanted sexual behaviour from the public last year. Concerningly, 8.67 per cent of 675,140 NHS workers who responded to the poll said they suffered sexual harassment from patients, patients' relatives, or other members of the public in 2023. Particularly, ambulance staff were affected, with nearly 25 per cent of staff reporting unwanted sexual behaviour from the public last year. According to the survey findings, 3.84 per cent of staff also encountered unwanted sexual behaviour from their colleagues. Dr Navina Evans, Chief Workforce, Training and Education Officer, described the survey results as "very distressing" and said that "such conduct should not be tolerated in the NHS." On the positive side, more NHS workers reported being happier at work and experiencing less burnout than before. Over half of the participants stated they look forward to coming to work, the highest number since 2020, as per the NHS. Dr Evans attributed this improvement to initiatives such as flexible working hours, clinical support squads to help menopausal women at work, and human resources stay advocates.

The UK Health Security Agency (UKHSA) and The Pirbright Institute have launched a new collaboration to develop vaccines against henipavirus, a genus of viruses that includes Nipah virus. Funded by the Medical Research Council, this research aims to develop a vaccine that provides cross protection against the whole genus, addressing the threat of outbreaks from new or emerging henipaviruses and strengthening epidemic preparedness. Scientists at UKHSA will evaluate the protective efficacy of vaccines developed by The Pirbright Institute by using use a model of Nipah virus disease, which mimics the infection in humans. Professor Isabel Oliver, chief scientific officer at UKHSA, stated that the study would improve understanding of henipaviruses and enhance efforts to protect health from this "current and future global health threat." "The work will also make a vital contribution to the 100 Days Mission - an important initiative to make sure the world is better prepared for the next pandemic by accelerating the development of diagnostics, therapeutics and vaccines," he added.

The incredible consequences that drug misuse has imposed on humans in the last few years make it one of the most pressing issues facing such nations. A person who is addicted to drugs or alcohol often turns to these substances as a crutch while they're going through tough times. Taking the drug regularly becomes habitual since it provides short-term relief without permanently resolving the issue. An important part of becoming sober is learning to substitute better routines for the addict's old, harmful ones. These self-care routines and healthy habits are much better ways to deal with stress. Here we will explain how healthy behavior throughout addiction recovery is simply one of many methods to adapt to life after treatment. Physical Activity Scientific studies have shown that physical activity increases levels of two hormones. dopamine and serotonin, which are linked to better mood. A more positive outlook, restful sleep, and enhanced general health are all possible outcomes of these hormones. In the early stages of your rehabilitation, it is wise to start an exercise regimen that you have never done before. You may find new sober friends and interactions, as well as inspiration to improve your physical health, by connecting with other people who share your interests in physical activity. In the early stages of recovery, having sober friends may be really helpful since it allows you to connect with those who understand what you're going through. Friendships formed in early recovery often continue long after the addict has left the program, according to many people in recovery.

Bristol-based Invatech Health has announced that it is fully funding the development of a new medical centre for families displaced by war and disaster in Northern Syria. The company has donated £54,000 to Action for Humanity for the medical centre, which would be part of a new village being constructed by the NGO, which provides clean water food, shelter, healthcare and education for millions of Syrians. According to the technology company, their donation is one of the charity's largest ever single donor contributions. The new village is set to accommodate 750 families, offering newly constructed homes, each featuring two bedrooms, a kitchen, and a bathroom.

MCAN Health, a medical travel company based in Istanbul-Turkey, has announced its sponsorship of National Pharmacy Association (NPA), a not-for-profit organisation representing independent community pharmacies across the UK. Gulsultan Dogan, the Founder and CEO of MCAN Health, said that their company is dedicated to improving global healthcare accessibility, which aligned perfectly with the NPA's mission to boost community health services in the United Kingdom. On receiving the invitation letter from the NPA, Dogan said: "We did not hesitate to show our support and positively answer the invitation letter. "As a professional in the healthcare sector for years, I firmly believe medical care is a human right that should be accessible to everyone without enduring lengthy waiting lists."

The Royal Pharmaceutical Society (RPS) and the Pharmacists' Defence Association (PDA) have responded to the Department of Health and Social Care (DHSC) consultation on pharmacy supervision, which was launched in early December last year. The DSHC set out proposals to amend the Medicines Act 1968 and The Human Medicines Regulations 2012 to allow registered pharmacy technicians to work without direct supervision, which in turn will help free up pharmacists to provide more clinical care and reduce GP appointments. While the RPS supported the legislative change, it highlighted a range of topics that should be considered and clarified in regulations and guidance. According to RPS, the new concept of 'authorisation', including around documentation, accountability, and the role of superintendent pharmacist and responsible pharmacist, needs clarification.

Novavax has announced the execution of a contract modification to extend the base period of performance of its current contract with the US Department of Health and Human Services, Biomedical Advanced Research and Development Authority