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The Structure of Scientific Revolutions by Thomas S. Kuhn, is an analysis of the history of science, published in 1962 by the University of Chicago Press. Its publication was a landmark event in the history, philosophy, and sociology of scientific knowledge and it triggered an ongoing worldwide assessment and reaction in—and beyond—those scholarly communities. In this work, Kuhn challenged the then prevailing view of progress in "normal science". Scientific progress had been seen primarily as "development-by-accumulation" of accepted facts and theories. Kuhn argued for an episodic model in which periods of such conceptual continuity in normal science were interrupted by periods of revolutionary science.

What is arguably the most famous example of a revolution in scientific thought is the Copernican Revolution. In Ptolemy's school of thought, cycles and epicycles (with some additional concepts) were used for modeling the movements of the planets in a cosmos that had a stationary Earth at its center. As accuracy of celestial observations increased, complexity of the Ptolemaic cyclical and epicyclical mechanisms had to increase to maintain the calculated planetary positions close to the observed positions. Copernicus proposed a cosmology in which the Sun was at the center and the Earth was one of the planets revolving around it.

Copernicus' contemporaries rejected his cosmology, and Kuhn asserts that they were quite right to do so: Copernicus' cosmology lacked credibility.

Consider global warming: Are you a global warming skeptic? Or are you skeptical of the global warming skeptics? In this case, I used to be a global warming skeptic, but now I'm skeptical of the global warming skeptics, which makes me a global warming believer based on the facts as I understand them at the moment. The "at the moment" part is what makes conclusions in science and skepticism provisional.

Thus, science and skepticism are synonymous, and in both cases it's okay to change your mind if the evidence changes. It all comes down to this question: What are the facts in support or against a particular claim?

Being a skeptic just means being rational and empirical: thinking and seeing before believing.

Hence Neel’s terrible experiments on the Yanomami, in a kind of grim downgrade of the Malthusian ethics of “Survivor.” He wanted to disprove the vulnerability of small, isolated groups to epidemics, seeking to show that though a disease such as measles might wreak awful havoc, his alpha-dominated males would be better adapted to evolve genetic immunity to these “contact” diseases. Many might die but the survivors would be of ever more superior stock. In their letter to the head of the Anthropological Association Turner and his colleague Sponsel write carefully that “Tierney’s well-documented account, in its entirety, strongly supports the conclusion that the epidemic was in all probability deliberately caused as an experiment designed to produce scientific support for Neel’s eugenic theory.”

We began this study assuming that, in Turner and Sponsel's words, we would be investigating 'an impending scandal' concerning flagrant wrongdoing by two celebrated scholars. Almost immediately, however, we discovered published evidence that the most serious allegations were false. Neel was not a eugenicist, did not cause the 1968 measles epidemic, and did not run nefarious experiments on unsuspecting human subjects. What he did was what any responsible physician would have done: vaccinate as many people as he could in a circle around the mission where the epidemic began. That these facts were available in the medical literature 30 years ago (Neel et al. 1970) made us wonder why Tierney had so badly distorted the facts. Perhaps it was because he had become an 'advocate,' to use his own words.

The first has to do with Tierney's use of an article by G. S. Wilson ("Measles as a Universal Disease," Amer. J of Diseases of Children 53: 219-23, 1962) to back up his claim that the Edmonston B measles vaccine is contraindicated. This is crucial to his broader argument that James Neel intentionally started a measles epidemic among the Yanomamo in 1968 by using this vaccine, and that he did this in order to observe its effect and test a eugenic theory.

Patrick Tierney's recent book Darkness in El Dorado makes very serious accusations of wrongdoing against Napoleon Chagnon, James Neel, and other scientists. Neel is accused of starting an epidemic among the Yanomamo in 1968 in order to observe its course as part of a secret experiment to test a eugenic theory. Chagnon is accused of aiding him, of fudging data, of staging events for his ethnographic films among other things, somehow causing the warfare that characterizes the Yanomamo.