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Bill Fulkerson

Radial flow system decouples reactions in automated synthesis of organic molecules - 0 views

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    The synthesis of structurally complex organic molecules is the first task in the discovery of functional compounds needed for new technologies, including those in medicine and flexible electronics. Starting with relatively simple, purchasable reactants, the process involves sequences of chemical reactions in which the complexity of the molecules produced gradually increases with each step towards the final target. The sequences can be linear, or convergent (different parts of the target molecule are made in separate sequences and then joined together). To ensure that large amounts of the final product are prepared, each synthetic step must be high-yielding and reproducible, and must generate few side products.
Bill Fulkerson

Why a 400-Year Program of Modernist Thinking is Exploding | naked capitalism - 0 views

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    " Fearless commentary on finance, economics, politics and power Follow yvessmith on Twitter Feedburner RSS Feed RSS Feed for Comments Subscribe via Email SUBSCRIBE Recent Items Links 3/11/17 - 03/11/2017 - Yves Smith Deutsche Bank Tries to Stay Alive - 03/11/2017 - Yves Smith John Helmer: Australian Government Trips Up Ukrainian Court Claim of MH17 as Terrorism - 03/11/2017 - Yves Smith 2:00PM Water Cooler 3/10/2017 - 03/10/2017 - Lambert Strether Why a 400-Year Program of Modernist Thinking is Exploding - 03/10/2017 - Yves Smith Links 3/10/17 - 03/10/2017 - Yves Smith Why It Will Take a Lot More Than a Smartphone to Get the Sharing Economy Started - 03/10/2017 - Yves Smith CalPERS' General Counsel Railroads Board on Fiduciary Counsel Selection - 03/10/2017 - Yves Smith Another Somalian Famine - 03/10/2017 - Yves Smith Trade now with TradeStation - Highest rated for frequent traders Why a 400-Year Program of Modernist Thinking is Exploding Posted on March 10, 2017 by Yves Smith By Lynn Parramore, Senior Research Analyst at the Institute for New Economic Thinking. Originally published at the Institute for New Economic Thinking website Across the globe, a collective freak-out spanning the whole political system is picking up steam with every new "surprise" election, rush of tormented souls across borders, and tweet from the star of America's great unreality show, Donald Trump. But what exactly is the force that seems to be pushing us towards Armageddon? Is it capitalism gone wild? Globalization? Political corruption? Techno-nightmares? Rajani Kanth, a political economist, social thinker, and poet, goes beyond any of these explanations for the answer. In his view, what's throwing most of us off kilter - whether we think of ourselves as on the left or right, capitalist or socialist -was birthed 400 years ago during the period of the Enlightenment. It's a set of assumptions, a particular way of looking at the world that pushed out previous modes o
Bill Fulkerson

zero sperm - 0 views

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    A strange thing has happened to men over the past few decades: We've become increasingly infertile, so much so that within a generation we may lose the ability to reproduce entirely. What's causing this mysterious drop in sperm counts-and is there any way to reverse it before it's too late?
Bill Fulkerson

Diverse interactions and ecosystem engineering can stabilize community assembly | Natur... - 0 views

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    The complexity of an ecological community can be distilled into a network, where diverse interactions connect species in a web of dependencies. Species interact directly with each other and indirectly through environmental effects, however to our knowledge the role of these ecosystem engineers has not been considered in ecological network models. Here we explore the dynamics of ecosystem assembly, where species colonization and extinction depends on the constraints imposed by trophic, service, and engineering dependencies. We show that our assembly model reproduces many key features of ecological systems, such as the role of generalists during assembly, realistic maximum trophic levels, and increased nestedness with mutualistic interactions. We find that ecosystem engineering has large and nonlinear effects on extinction rates. While small numbers of engineers reduce stability by increasing primary extinctions, larger numbers of engineers increase stability by reducing primary extinctions and extinction cascade magnitude. Our results suggest that ecological engineers may enhance community diversity while increasing persistence by facilitating colonization and limiting competitive exclusion.
Steve Bosserman

How Artists Are Bringing Blockchain to Their Neck of the Woods - 0 views

  • It’s also a process that upends our deeply rooted legal norms that attach ownership to people. If we have historically tied ownership to the concept of natural or legal persons, what then happens, asks Kolling, if a non-human agent, whether a natural entity or a computer program, gains the ability to own? “Wouldn’t this ability come along with some kind of personhood?”
  • Kolling and his terra0 co-founders are part of a broader wave that’s ushering blockchain into the art world. Some are merely using the technology to verify the authenticity of particular works, but many artists want to go further. “Every system which plainly reproduces the old one is quite boring,” says Seidler, 29, who’s a head shorter than the lanky Kolling. “What interests me is using distributed ledgers as experimental systems where issues of autonomy, value and cooperation can be renegotiated.”
Steve Bosserman

High score, low pay: why the gig economy loves gamification | Business | The Guardian - 0 views

  • Simply defined, gamification is the use of game elements – point-scoring, levels, competition with others, measurable evidence of accomplishment, ratings and rules of play – in non-game contexts. Games deliver an instantaneous, visceral experience of success and reward, and they are increasingly used in the workplace to promote emotional engagement with the work process, to increase workers’ psychological investment in completing otherwise uninspiring tasks, and to influence, or “nudge”, workers’ behaviour.
  • According to Burawoy, production at Allied was deliberately organised by management to encourage workers to play the game. When work took the form of a game, Burawoy observed, something interesting happened: workers’ primary source of conflict was no longer with the boss. Instead, tensions were dispersed between workers (the scheduling man, the truckers, the inspectors), between operators and their machines, and between operators and their own physical limitations (their stamina, precision of movement, focus). The battle to beat the quota also transformed a monotonous, soul-crushing job into an exciting outlet for workers to exercise their creativity, speed and skill. Workers attached notions of status and prestige to their output, and the game presented them with a series of choices throughout the day, affording them a sense of relative autonomy and control. It tapped into a worker’s desire for self-determination and self-expression. Then, it directed that desire towards the production of profit for their employer.
  • Former Google “design ethicist” Tristan Harris has also described how the “pull-to-refresh” mechanism used in most social media feeds mimics the clever architecture of a slot machine: users never know when they are going to experience gratification – a dozen new likes or retweets – but they know that gratification will eventually come. This unpredictability is addictive: behavioural psychologists have long understood that gambling uses variable reinforcement schedules – unpredictable intervals of uncertainty, anticipation and feedback – to condition players into playing just one more round.
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  • Gaming the game, Burawoy observed, allowed workers to assert some limited control over the labour process, and to “make out” as a result. In turn, that win had the effect of reproducing the players’ commitment to playing, and their consent to the rules of the game. When players were unsuccessful, their dissatisfaction was directed at the game’s obstacles, not at the capitalist class, which sets the rules. The inbuilt antagonism between the player and the game replaces, in the mind of the worker, the deeper antagonism between boss and worker. Learning how to operate cleverly within the game’s parameters becomes the only imaginable option. And now there is another layer interposed between labour and capital: the algorithm.
Steve Bosserman

A radio play about radio that became the first fake-news story | Aeon Essays - 0 views

  • The broadcast has become an origin story of fake news and technological anxiety in the United States, and its tentacled aliens watch when we talk of fake news today. Then, as now, the worry over whether the news can be believed was a proxy for something else entirely – fear of the new technologies that brought it. Scholars have convincingly questioned the scale of the 1938 panic. Everybody loves a good story – especially the newspapers threatened by radio news, the social scientists seeking a claim to relevance, and Welles, great ham that he was. Firsthand accounts attest that some listeners did panic, but many more did not. Why, then, did millions more find the panic so easy to believe these past 80 years?
  • In that decade, radio became more trusted than newspapers. The reasons had to do partially with the unique characteristics of the medium – its intimacy and ability to put you on the spot to hear as an event unfolded without a reporting gap in which craven newspapermen could insert their own slant. It also had to do with the trueness of the sounds that radio reproduced.
  • In November, three days after the War of the Worlds broadcast, Dorothy Thompson, a syndicated columnist and radio reporter, published an oft-cited piece in response, entitled ‘Mr Welles and Mass Delusion’, in which she argued that the broadcast suggested American susceptibility to foreign propaganda:All unwittingly Mr Orson Welles and the Mercury Theatre of the Air have made one of the most fascinating and important demonstrations of all time. They have proved that a few effective voices, accompanied by sound effects, can so convince masses of people of a totally unreasonable, completely fantastic proposition as to create nationwide panic … If people can be frightened out of their wits by mythical men from Mars, they can be frightened into fanaticism by the fears of Reds, or convinced that America is in the hands of 60 families, or aroused to revenge against any minority, or terrorised into subservience to leadership because of any imaginable menace.
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  • The new trajectory changed news from an informative tool to an expressive one, and upended older reader-to-journalist relationships that looked almost more like a student-to-teacher relationship, albeit one entered into by choice. Though readers could always share stories, social media propelled the act. Readers can share stories because they feel true, and lend those stories emotional rather than factual force.
  • There are plenty of reasons the fake news concern of today does not exactly parallel the War of the Worlds story– among them, the fact that a large part of the modern worry is the degree to which lone actors can create the illusion of legitimacy online. But as with War of the Worlds, any individual piece of fake news – like the false story that Pope Francis endorsed President Trump – is not the only concern.More than the news, we fear the technology that transmits it. The quintessential Martians are those ways of knowing that are enabled by our new machines, threatening to make the solid world make-believe once more.
Steve Bosserman

How the sufferings of one generation are passed on to the next | Aeon Essays - 0 views

  • Those findings apply to a single generation, yet they tug at the edges of evolutionary theory, in which species change slowly over millennia, not rapidly over the months or years of a single life. Charles Darwin’s process of natural selection holds that nature choses the best-adapted organisms to reproduce and survive in any given ecosystem. The process operates when DNA sequences mutate randomly, and organisms with the specific sequences best-adapted to the environment multiply and prevail – causing gene expression to shift. Yet as surely as the slow march of Darwinian evolution shapes life on Earth over aeons, scientists have found that epigenetic signals can work each day, and not just through methyl groups. Experience in the environment could also alter chromatin, the molecular matrix making up our chromosomes; RNA, the messenger molecules that translate genetic instructions from DNA into protein; and histones, the proteins involved in packaging and structuring the chromatin comprising the genes.
Bill Fulkerson

Famous economics experiment reproduced thousands of times - 0 views

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    In an open marketplace, such as a farmers' market where produce and other goods like candles and flowers are exchanged for money, the ideal prices for both consumers and sellers will quickly emerge. For example, if a seller tries to offer a bag of peaches for $10 but another vendor is willing to sell similar peaches for $5, the lower price will eventually win out and become the norm. This phenomenon, which is related to the law of supply and demand, was demonstrated experimentally starting in the 1960s by Caltech alumnus and Nobel Laureate Vernon Smith (BS '49), now at Chapman University, and later by Caltech's Charlie Plott, the William D. Hacker Professor of Economics and Political Science.
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