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(CNN) -- Anything creative begins with a question. The problem is that questions take us into uncertainty, which is a very dangerous place to be. If there were a predator next to you and your brain wasn't absolutely sure what to do, then it'd probably be too late. The need to translate ambiguous sensory information into meaningful behavior has been the fundamental drive of brain evolution, without which survival in a complex world would not have been possible. And yet a deep irony is that the best questions -- i.e., the ones that challenge our deepest sense of what is true -- create the most uncertainty.

July 9, 2012 Early Computing's 'Deal With the Devil' Victoria StoddenGeorge Dyson, son of the physicist Freeman Dyson and author of Turing's Cathedral, grew up playing with discarded bits of early computers at Princeton's Institute for Advanced Study.Enlarge Image By Marc Parry In 1936, the British logician Alan Turing imagined a universal computing machine. In the wake of World War II, at Princeton's Institute for Advanced Study, a team of mathematicians and engineers built one. The machine stood roughly the size of four refrigerators. People called it Maniac, for Mathematical and Numerical Integrator and Computer. At its heart was "a 32-by-32-by-40 bit matrix of high-speed, random-access memory-the nucleus of all things digital ever since," writes George Dyson in a new book, Turing's Cathedral (Pantheon Books). How that computer came to be, he says, is the story of "a deal with the devil." Mathematicians built a machine that helped create the hydrogen bomb. In exchange, they got a new breed of computer that enabled incredible scientific progress.