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A pulse oximeter is typically used for target diseases, which include measles, tuberculosis, tetanus, etc. Recently, hepatitis B and yellow fever have also been added to the list of the target diseases.

The use of vital sign monitoring devices in hospitals allows doctors to look for signs of potential life-threatening complications before the patient reaches the critical stages. Patients can often be monitored throughout the night with a pulse oximeter, ECG, blood pressure and oxygen saturation monitoring devices. These devices are also useful for monitoring the effect of medication and other treatments on the body.