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The HPAPIs and cytotoxic drugs manufacturing polarity independent safety tests have been developed by several pharmaceutical companies. These chemical agents are required to be kept below the safety standards specified by the US Food and Drug Administration (FDA). However, the current safety guidelines published by the FDA do not include these medications.

The HPAPIs and cytotoxic drugs fabricating extremity free security tests have been created by a few drug organizations. These substance specialists are needed to be kept beneath the security standards determined by the US Food and Drug Administration (FDA).