A study on the effects of Apolipoprotein A-IV in food intake regulation - 1 views

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  #1 Johnny James on 27 Jan 14

   

  Apolipoprotein A-IV(APOA4) resides on chromosome 11 in shut linkage to APOA1 and APOC3. APOA4 contains 3 exons separated by 2 introns, and is polymorphic, most of the reportable sequence polymorphisms occur in exon 3. The translation product of the APOA4 is a 396-residue preprotein, that undergoes chemical process process to yield APOA4, a 376-residue mature O-linked compound protein. In most mammals, together with humans, Apolipoprotein A-IV synthesis is confined to the intestine, but in mice and rats internal organ synthesis conjointly happens. Apolipoprotein A-IV is secreted into circulation on the surface of fresh synthesized corpuscle particles. Enteric fat absorption dramatically will increase the synthesis and secretion of APOA4. uingbbcosk
  Apolipoprotein A-IV is a glycoprotein synthesized by the human viscus. In rodents, the small viscus and the liver secrete APOA4. The small viscus, however, is by far the most important organ liable for the current APOA4. Enteric APOA4 synthesis is markedly stirred up by fat absorption and seems to not be mediate by the uptake or reesterification of fatty acids to create triglycerides. Rather, it's the formation of chylomicrons that acts as a symbol for the induction of enteric APOA4 synthesis. APOA4 synthesis is additionally increased by a factor from the small intestine which factor is probably peptide tyrosine-tyrosine(PYY). The inhibition of food intake by APOA4 is perhaps mediate centrally. Apolipoprotein ccl11 elisa kit http://www.cusabio.com/bio1-C-CCL11-7-7.html employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for APOA4 has been pre-coated onto a microplate. Apolipoprotein A-IV ELISA Kit has high sensitivity and excellent specificity for detection of APOA4. The stimulation of enteric synthesis and secretion of APOA4 by protein absorption are fast, APOA4 plays a role in the short-run regulation of food intake. APOA4 can be concerned in the long-run regulation of food intake and weight. Chronic body process of a high fat diet blunts the enteric APOA4 response to protein feeding and make a case for why the chronic body process of a high fat diet predisposes each animals and humans to fatness.

   

  <div class="cArrow"> </div><div class="cContentInner">Apolipoprotein A-IV(APOA4) resides on chromosome 11 in shut linkage to APOA1 and APOC3. APOA4 contains 3 exons separated by 2 introns, and is polymorphic, most of the reportable sequence polymorphisms occur in exon 3. The translation product of the APOA4 is a 396-residue preprotein, that undergoes chemical process process to yield APOA4, a 376-residue mature O-linked compound protein. In most mammals, together with humans, Apolipoprotein A-IV synthesis is confined to the intestine, but in mice and rats internal organ synthesis conjointly happens. Apolipoprotein A-IV is secreted into circulation on the surface of fresh synthesized corpuscle particles. Enteric fat absorption dramatically will increase the synthesis and secretion of APOA4. uingbbcosk <br /> Apolipoprotein A-IV is a glycoprotein synthesized by the human viscus. In rodents, the small viscus and the liver secrete APOA4. The small viscus, however, is by far the most important organ liable for the current APOA4. Enteric APOA4 synthesis is markedly stirred up by fat absorption and seems to not be mediate by the uptake or reesterification of fatty acids to create triglycerides. Rather, it's the formation of chylomicrons that acts as a symbol for the induction of enteric APOA4 synthesis. APOA4 synthesis is additionally increased by a factor from the small intestine which factor is probably peptide tyrosine-tyrosine(PYY). The inhibition of food intake by APOA4 is perhaps mediate centrally. Apolipoprotein ccl11 elisa kit <a href="http://www.cusabio.com/bio1-C-CCL11-7-7.html" rel="nofollow" target="_blank">http://www.cusabio.com/bio1-C-CCL11-7-7.html</a> employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for APOA4 has been pre-coated onto a microplate. Apolipoprotein A-IV ELISA Kit has high sensitivity and excellent specificity for detection of APOA4. The stimulation of enteric synthesis and secretion of APOA4 by protein absorption are fast, APOA4 plays a role in the short-run regulation of food intake. APOA4 can be concerned in the long-run regulation of food intake and weight. Chronic body process of a high fat diet blunts the enteric APOA4 response to protein feeding and make a case for why the chronic body process of a high fat diet predisposes each animals and humans to fatness.</div>

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