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Primary hypotensive reaction is a rare type of transfusion reaction caused by excess bradykinin in the blood product, which is typically not screened for during packed red blood cell preparation. Here, we describe a patient who experienced hypotension during blood transfusion that could not be attributed to other life-threatening reactions such as acute hemolytic reaction, anaphylaxis, transfusion-related acute lung injury, or sepsis.

With regard to transplantation is carried out conventional therapy in most cases (81%) also on adult patients with good results, is procendendo more and more with the transplantation of stem cells (16%) and finally gene therapy, where he is studying the possibility of genes able to produce hemoglobin in an appropriate manner.

Drug and Iron Chelation Therapy Drugs to treat hemochromatosis: iron accumulation in the blood is one of the most immediate consequences resulting from frequent blood transfusions, which needs a thalassemia. To cope with hemochromatosis, the doctor suggests, generally, a therapy with chelating drugs, which can, therefore, to sequester the iron accumulated in the blood and eliminate it through urination.