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Wang C, Harris WS, Chung M, Lichtenstein AH, Balk EM, Kupelnick B, Jordan HS, Lau J. \nn-3 Fatty acids from fish or fish-oil supplements, but not \nalpha-linolenic acid, benefit cardiovascular disease outcomes in \nprimary- and secondary-prevention studies: a systematic review. \nAm J Clin Nutr. 2006 Jul;84(1):5-17. Review. \nPMID: 16825676

ScienceDaily (Feb. 11, 2009) - New research from Columbia University Medical Center continues to shed light on the benefits of making fish a staple of any diet.

Prevention of insulin resistance by n-3 polyunsaturated fatty acids. Fedor D, Kelley DS. Curr Opin Clin Nutr Metab Care. 2009 Mar;12(2):138-46. PMID: 19202385

What causes coronary heart disease or coronary atherosclerotic plaque, this thing that we track with heart scans? \n\nWell, here are a few little-publicized facts about heart disease that you are unlikely to hear from your When's-the-next-stent? cardiologist or the What is there besides statins? primary care doctor. \n\n(Since everybody knows that smoking is a modifiable risk for heart disease that can be readily identified, let's focus on the blood tests that reveal heart disease causes.)

Lin PY, Su KP. A meta-analytic review of double-blind, placebo-controlled trials of antidepressant efficacy of omega-3 fatty acids. J Clin Psychiatry. 2007 Jul;68(7):1056-61. PMID: 17685742 [PubMed - in process]

Severus WE. Effects of omega-3 polyunsaturated fatty acids on depression. Herz. 2006 Dec;31 Suppl 3:69-74. Review. PMID: 17575808 [PubMed - indexed for MEDLINE]