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Recombinant Gliadinfragment (storage protein from wheat (Triticum aestivum) grain). cDNAcoding for an epitope-carrying fragment of a wheat gamma-gliadin isoform,fused to a hexa-histidine purification tag. Expressed in E.coli bacterial cells.

antibody producing cell: Repetitive Immunizations Multiple Sites (RIMMS) Services, obtain hybridomas rapidly

Glutamate receptors are located in both neurons and glial cells throughout the CNS. The glutamatergic synapse pathways, which are linked to many other neurotransmitter pathways, play a crucial role in a large array of normal physiological functions. The glutamate dysfunction stands out as a key factor in both neurodevelopmental diseases and injury.

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter that widely distributed in the vertebrate central nervous system (CNS). As a phylogenetically ancient signaling molecule, 5-HT serves as a target of numerous physiologic regulators, including modulators of gene transcription, neurotrophic factors and steroids.

Inflammasome activation is a key function mediated by the innate immune system in response to harmful stimuli, such as pathogens, dead cells or irritants. However, overt activation of inflammasomes may also lead to a variety of autoinflammatory and autoimmune diseases, including neurodegenerative diseases (such as multiple sclerosis, Alzheimer's disease and Parkinson's disease) and metabolic disorders (such as atherosclerosis, obesity and type II diabetes).

Canonical processing of APP is catalyzed by α-secretase, resulting in the generation of two fragments: a large extracellular fragment secreted APP (sAPP) α (sAPPα) that is released to extracellular medium, as well as an83 amino acid C-terminal fragment α-carboxyterminal fragments (CTF) that remains in the membrane.

Gamma-Aminobutyric acid (γ-Aminobutyric acid, GABA) is the predominating inhibitory neurotransmitter in the mammalian CNS. As exogenous GABA cannot penetrate the blood-brain barrier, it is synthesized in the GABAergic neurons in the CNS, converted from glutamate, the principal excitatory neurotransmitter, using the enzyme glutamic acid decarboxylase (GAD) and pyridoxal phosphate as a cofactor.

Phosphorylation is the most common and important molecular mechanism of acute and reversible regulation of protein function. Through protein phosphorylation, protein function is regulated in response to extracellular stimuli both inside and outside the cell.

Neuroinflammatory response is primarily an inherent protective mechanism in the central nervous system (CNS). In intact nerves of the CNS, glial cells (including astrocytes and microglia) play a key role in critical support, and can respond to any degree of CNS injury and disease.

This virus is classified in the BSL 3 category. This Western equine encephalitis virus[47a-Original reference strain (=California horse).] is preserved under Freeze Dried (-20°C).Tests for the presence of mycoplasmae were positive.

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