Use of cod liver oil during the first year of life is associated with lower risk of childhood-onset type 1 diabetes: a large, population-based, case-control study.
Stene LC, Joner G; Norwegian Childhood Diabetes Study Group.
Am J Clin Nutr. 2003 Dec;78(6):1128-34.
PMID: 14668274
Conclusion: Cod liver oil may reduce the risk of type 1 diabetes, perhaps through the antiinflammatory effects of long-chain n-3 fatty acids.
Outcomes evaluation suggests that BrennerFIT participants have reduced their body mass index and cardiovascular risk factors, while post-implementation data and surveys show a low dropout rate and high levels of patient/family satisfaction with the program.
Not enough vitamin D: health consequences for Canadians.
Schwalfenberg G.
Can Fam Physician. 2007 May;53(5):841-54. Review
PMID: 17872747
Conclusion
Low levels of VTD are considered a major public health problem in Canada, especially during the winter. Those with risk factors should be screened for low 25(OH)D levels and repletion therapy instituted if needed. Researchers have estimated that the oral dose of vitamin D3 to attain and maintain 25(OH)D levels >80 nmol/L is 2200 IU/d if baseline levels are 20 to 40 nmol/L, 1800 IU/d if levels are 40 to 60 nmol/L, and 1160 IU/d if levels are between 60 and 80 nmol/L.64
We need to ensure that patients have healthy blood levels of 25(OH)D to prevent levels of parathyroid hormone from rising and to maximize absorption of calcium, magnesium, and phosphate. Positive effects on bone are marginal at best unless patients consume at least 800 IU/d of VTD. The emerging and exciting role of the VTD receptor and the actions of VTD in maintaining health in other cell types have become more apparent during the last decade.
Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction.
Chiu KC, Chu A, Go VL, Saad MF.
Am J Clin Nutr. 2004 May;79(5):820-5.
PMID: 15113720
Conclusions: The data show a positive correlation of 25(OH)D concentration with insulin sensitivity and a negative effect of hypovitaminosis D on ß cell function. Subjects with hypovitaminosis D are at higher risk of insulin resistance and the metabolic syndrome. Further studies are required to explore the underlying mechanisms.
The program, which involved two distinct project periods (1999-2000 for planning and 2000-2007 for implementation), improved health-related skills and behaviors (e.g., eating more healthfully, engaging in more physical activity), leading to anecdotal reports of better health.
To investigate whether lower risk HLA class II genotypes would influence the efficacy of DiaPep277 therapy in protecting β-cell function evaluated by C-peptide secretion in recent-onset type 1 diabetic subjects.
