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"The theme of the 175th Annual Meeting of the American Association for the Advancement of Science (AAAS), "Our Planet and Its Life, Origins, and Futures," celebrated an enormous breadth of scientific accomplishments that transcends many subdisciplines of the natural and social sciences. It was intended to be both a reflection on what has been learned and a look forward to what must yet be better known if we are to make wise choices as stewards of our planet. The program committee saw this as an opportunity to examine how we have come to know and understand the coevolution of life with its interacting biological, biogeochemical, and physical environments. Further advances in this area are essential to develop scenarios that can be useful in guiding decisions to address some of society's most pressing problems. We must work toward a future that embraces the wise application of science to improve human health and well-being and to sustain the great diversity of life on our planet. "