e Flavivirus. Acute means it comes on (onset) rapidly, while systemic means it affects the whole body. In severe cases yellow fever causes a high fever, bleeding into the skin and the death of cells in the liver and kidneys. Liver damage results in severe jaundice - yellowing of the skin; hence the name "yellow fever".

Yellow fever causes 200,000 infections and 30,000 deaths every year

Since the 1980s, the number of cases of yellow fever has been increasing.[6][2] This is believed to be due to fewer people being immune,

more people living in cities, people moving frequently, and changing climate.[2] The disease originated in Africa, where it spread to South America through the slave trade in the 17th century.[1] Since the 17th century, several major outbreaks of the disease have occurred in the Americas, Africa, and Europe.[1] In the 18th and 19th centuries, yellow fever was seen as one of the most dangerous infectious diseases.[1] The yellow fever virus was

llow fever can be prevented by vaccination. Travelers should also take precautions against mosquito bites when in areas with yellow fever transmission. Travelers should get vaccinated for yellow fever before visiting areas where yellow fever is found.