After an incubation period of 5-10 days, the onset of the
disease is sudden and is marked by fever, chills, headache, and myalgia. Around
the fifth day after the onset of symptoms, a maculopapular rash, most prominent
on the trunk (chest, back, stomach), may occur. Nausea, vomiting, chest pain, a
sore throat, abdominal pain, and diarrhea then may appear. Symptoms become
increasingly severe and may include jaundice, inflammation of the pancreas,
severe weight loss, delirium, shock, liver failure, massive hemorrhaging, and
multi-organ dysfunction.