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J. B.

Confrontation all the way : Pharyngula - 0 views

  • the great unifying principle of my discipline
  • wallowing in self-inflicted ignorance
  • weird fantasies
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  • religious zealots who have been poisoning the minds of the young
  • Gnu Atheists are so dang angry. Damned right we are. The real question is why everyone else isn't.
  • Idiot America
  • The sea our country is drowning in is a raging religiosity, wave after wave of ignorant arguments and ideological absurdities pushed by tired dogma and fervent and frustrated fanatics.
  • The solution, the only longterm solution, is the sanity of secularism.
  • pseudoscientific BS like intelligent design
  • disease
  • if you're one of those people trying to defend superstition and quivering in fear at the idea of taking on a majority that believes in foolishness, urging us to continue slapping bandages on the blight of faith, well then, you're part of the problem and we'll probably do something utterly dreadful, like be rude to you or write some cutting sarcastic essay to mock your position. That is our métier, after all.
  • the Gnu Atheists have values, too, and premiere among them is truth. And that makes us uncivil and rude, because we challenge the truth of religion.
  • Evolution is a real, and it is a process built on raw chance driven by the brutal engines of selection, and there is no sign of a loving, personal god, but only billions of years of pitiless winnowing without any direction other than short-term survival and reproduction. It's not pretty, it's not consoling, it doesn't sanctify virginity, or tell you that god really loves your foreskin, but it's got one soaring virtue that trumps all the others: it's true.
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    Atheist PZ Myers defends his anger toward religious people and has an interesting statement on what he believes the implications of Darwinism are (for those who consider themselves "Theistic Evolutionists").
J. B.

The Disenchanted Naturalist's Guide to Reality « On the Human - 0 views

  • It is one that most naturalists have sought to avoid, or at least qualify, reinterpret, or recast to avoid its harshest conclusions about the meaning of life, the nature of morality, the significance of our consciousness self-awareness, and the limits of human self-understanding.
  • Scientism is my label for what any one who takes science seriously should believe, and scientistic is just an in-your face adjective for accepting science’s description of the nature of reality.
  • the answers to the persistent questions are not what people want to hear, and the bad news may lead them to kill the messenger—scientific research
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  • So, scientists have an incentive to cover up
  • the mechanism Darwin discovered for building adaptations is the only game in town. Any explanation of the very existence of even the slightest adaptation must be Darwinian. 
  • Ever since Newton physics has ruled out purposes in the physical realm. If the physical facts fix all the facts, however, then in doing so, it rules out purposes altogether, in biology, in human affairs, and in human thought-processes.
  • The fundamental laws of nature are mostly timeless mathematical truths that work just as well backwards as forward, and in which purposes have no role.
  • the process that Darwin discovered–random, or rather blind variation, and natural selection, or rather passive environmental filtration–does all the work of explaining the means/ends economy of biological nature that shouts out ‘purpose’ or ‘design’ at us. What Darwin showed was that all of the beautiful suitability of living things to their environment, every case of fit between organism and niche, and all of the intricate meshing of parts into wholes, is just the result of blind causal processes. It’s all just the foresightless play of fermions and bosons producing, in us conspiracy-theorists, the illusion of purpose.
  • When it comes to life, natural selection, it turns out, is the only game in town.
  • One source of meaning on which many have relied is the intrinsic value, in particular the moral value, of human life. People have also sought moral rules, codes, principles which are supposed to distinguish us from merely biological critters whose lives lack (as much) meaning or value (as ours). Besides morality as a source of meaning, value, or purpose, people have looked to consciousness, introspection, self-knowledge as a source of insight into what makes us more than the merely physical facts about us. Scientism must reject all of these straws that people have grasped, and it’s not hard to show why. Science has to be nihilistic about ethics and morality.
  • Just because there is strong selection for a moral norm is no reason to think it right. Think of the adaptational benefits of racist, xenophobic or patriarchal norms. You can’t justify morality by showing its Darwinian pedigree.
  • The process of natural selection is not in general good at filtering for true beliefs, only for ones hitherto convenient for our lines of descent.
  • we can’t invest our moral core with more meaning than this: it was a convenience, not for us as individuals, but for our genes. There is no meaning to be found in that conclusion.
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    Alex Rosenberg pops the Naturalist's bubble.
J. B.

Et tu, Pseudogenes? Another Type of "Junk" DNA Betrays Darwinian Predictions - Evolutio... - 0 views

  • Genomes are littered with nonfunctional pseudogenes, faulty duplicates of functional genes that do nothing, while their functional cousins (the word doesn't even need scare quotes) get on with their business in a different part of the same genome.
    • J. B.
       
      Does this mean Dawkins is arguing Atheism of the Gaps? (e.g., We don't know what these genes are for, therefore they must be junk. Therefore, there must not be a Creator.)
  • Once again, creationists might spend some earnest time speculating on why the Creator should bother to litter genomes with untranslated pseudogenes and junk tandem repeat DNA.
  • recent results are challenging this moniker; indeed, some pseudogenes appear to harbor the potential to regulate their protein-coding cousins. Far from being silent relics, many pseudogenes are transcribed into RNA, some exhibiting a tissue-specific pattern of activation. Pseudogene transcripts can be processed into short interfering RNAs that regulate coding genes through the RNAi pathway. In another remarkable discovery, it has been shown that pseudogenes are capable of regulating tumor suppressors and oncogenes by acting as microRNA decoys.
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  • In some cases, what appears to be a nontranslated pseudogene can, in fact, code for truncated proteins (Kandouz et al. 2004; Zhang et al. 2006). Nevertheless, the evidence that some pseudogenes can exert regulatory effects on their protein-coding cousins is mounting.
  • For the large part, pseudogenes have been overlooked in the quest to understand the biology of health and disease, to the extent that pseudogene probes are often absent from commercially available microarrays. As evidence emerges that pseudogenes are deregulated in disease, and indeed that their deregulation can contribute to diseases such as diabetes and cancer, the prevalent attitude that they are nonfunctional relics is slowly changing.
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