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Lee Vander Loop

Newly Paralyzed Start Here - Spinal Cord Injury - Paralysis Research Center - 0 views

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    Promotes the health and well-being of people living with a spinal cord injury, mobility impairment and paralysis by providing comprehensive information, resources and referral services.
Lee Vander Loop

New Common Pathway in Neurodegenerative Disease is a Possible Door to a Point of No Ret... - 0 views

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    "The focus of the study is on the plentiful neurons that communicate with each other through the neurotransmitter glutamate. While glutamate is a necessary excitatory substance in the nervous system, in excess, it overstimulates and becomes toxic - excitotoxic - to neurons. Fortunately, neighboring astrocytes can mop up the excess via molecular transporters embedded in their outer membranes. The chief transporter is a protein called EAAT2. Earlier Rothstein's group showed that astroglia - and their EAAT2 protein - are critical for normal neuron activity. In test rats whose astroglia lack the EAAT2 equivalent there's not only a flood of toxic glutamate but a resulting neuron death that leads to paralysis."
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