n international consortium led by Baylor College of Medicine and The University of Texas M.D. Anderson Cancer Center has narrowed the search for the gene or genes associated with inherited susceptibility to glioma, a deadly form of brain Cancer, to a region on chromosome 17.
Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas.
Blázquez C, González-Feria L, Alvarez L, Haro A, Casanova ML, Guzmán M.
Cancer Res. 2004 Aug 15;64(16):5617-23.
PMID: 15313899
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
Blázquez C, Salazar M, Carracedo A, Lorente M, Egia A, González-Feria L, Haro A, Velasco G, Guzmán M.
Cancer Res. 2008 Mar 15;68(6):1945-52.
PMID: 18339876
doi: 10.1158/0008-5472.CAN-07-5176