The active compound in marijuana, THC, can slow the growth of lung tumours and reduce the spread of the cancer in mice, a preliminary study reveals.
Human lung cancer tumours grew less than half as fast in mice that received moderate doses of the compound, the researchers reveal. They hope that drugs mimicking the apparent anti-cancer effects of tetrahydrocanabinol (THC) could one day help treat patients. The team strongly discourage people from self-medicating by smoking marijuana, noting that doing so could potentially encourage tumour growth.
Researchers investigating the role of cannabis in cancer therapy reveal it has the potential to destroy leukaemia cells, in a paper published in the March 2006 edition of Letters in Drug Design & Discovery. Led by Dr Wai Man Liu, at Barts and the London, Queen Mary's School of Medicine and Dentistry, the team has followed up on their findings of 2005 which showed that the main active ingredient in cannabis, tetrahydrocannabinol, or THC, has the potential to be used effectively against some forms of cancer. Dr Liu has since moved to the Institute of Cancer in Sutton where he continues his work into investigating the potential therapeutic benefit of new anti-cancer agents.
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PMID: 15629274
doi:10.1016/S1470-2045(04)01711-5
By Randy Dotinga
HealthDay Reporter
MONDAY, Jan. 11 (HealthDay News) -- Preliminary research suggests that a combination of compounds in marijuana could help fight off a particularly deadly form of brain cancer.
But the findings shouldn't send patients rushing to buy pot: the levels used in the research appear to be too high to obtain through smoking. And there's no sign yet that the approach works in laboratory animals, let alone people.