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Human Papillomavirus (HPV) Genotyping Detection HPV is a virus that causes cancer and can be further subdivided into high-risk and low-risk types. Cervical cancer can only result from persistent infection with high-risk HPV. Cervical cancer is the only form of cancer that can be prevented and cured if caught at an early stage due to a known and treatable cause. When it comes to reducing the incidence and mortality rates associated with cervical cancer, HPV screening is the most effective and direct method of prevention, detection, diagnosis, and treatment.