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Fetal Chromosomal Aneuploidies and Microdeletions/ Microduplications Detection (NIPT-Plus) Fetal Chromosomal Aneuploidies and Microdeletions/ Microduplications Detection (NIPT-Plus) can find 100 chromosomal diseases at once, including 3 common chromosomal aneuploidies, 4 sex chromosomal aneuploidies, and 93 microdeletion duplication syndromes.

Trisomy 21 (Down syndrome), trisomy 18 (Edward's syndrome), and trisomy 13 (Patau's syndrome) are the three most prevalent autosomal aneuploid diseases. The incidence in newborns is 1/(600-800), 1/(3500-8000), and 1/(7000-20000). Intellectual disability, developmental delay, multiple deformities, reproductive disorders, etc. are common in children. Using a fetal chromosome aneuploidy (T21, T18, T13) detection kit (semiconductor sequencing), doctors can reliably identify these conditions in unborn children (trisomy 21, trisomy 18, and trisomy 13).

Fetal Aneuploidies (Trisomy 21, Trisomy 18 and Trisomy 13) Detection IVD Medical Device | Capitalbio

HLA Typing The HLA (human leucocyte antigen) system encodes the major histocompatibility complex (MHC) proteins in humans, is closely related to the body's immune system. The HLA gene complex is located on a 3.6 Mb region within chromosome 6p21. They are the most polymorphic gene family found in the human genome, with more than 10,000 different HLA alleles reported to date, thus the capacity to mount an immune response can be remarkably different between individuals within a cohort selected from a single population. HLA genes have been strongly implicated in transplant rejection, autoimmune disease, vaccine pharmacogenomics, cancer and infectious diseases. HLA genotyping is the identification of the HLA class I and class II gene polymorphisms for individuals, which is indispensable for transplant matching and disease association studies.