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According to research reports, individuals with inherited cancer genes have a higher risk of cancer than ordinary people. About 7% of breast cancer and 1%-15% of ovarian cancer are caused by BRCA1/BRCA2 gene mutations. In families with a high incidence of breast and ovarian cancer, 80% of patients have mutations in the BRCA1/BRCA2 gene, and this gene is inherited in an autosomal dominant manner in the population. This test detects the entire coding region of BRCA1/BRCA2 genes, and 20bp intron regions upstream and downstream of the coding region, in addition to known mutation hotspot genes, unknown mutations can be detected.

Genetic Testing for BRCA1/2 Targeted-drug Guidance [ Germline + Somatic] This test detects somatic and germline SNV, InDel and CNV mutations in the BRCA1 and BRCA2 genes, covering the entire coding region of the BRCA1/2 gene and both flanking intron regions, provide information to guide PARP inhibitor therapy in breast & ovarian cancer.