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Researchers have remotely activated genes inside living animals, a proof of concept that could one day lead to medical procedures in which patients' genes are triggered on demand. The work, in which a team used radio waves to switch on engineered insulin-producing genes in mice, is published today in Science1.

"In recent years, researchers in the messy world of biology have been able to build systems that function like the clean, binary switches on computer chips-and we've covered a number of reports in this area. Unfortunately, most of these share a significant limitation: they rely on proteins from bacteria that act as switches to turn genes on and off under specific conditions. We know about only a limited number of these genetic switches, which may set a severe limit on the number of logical operations we can string together inside a cell."