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SEQanswers is a discussion forum and information source for next generation sequencing.

I am Candy Swift from Creative Biolabs. We have established the GHA® platform to germinalize humanized antibodies. Antibody humanization followed by germinalization produces human antibodies with excellent germinality index (GI). Human antibodies optimized from this platform are almost equivalent to mature human antibodies in sequence and have minimal immunogenicity while retaining parental affinity and specificity... Read full article at http://www.scientistsolutions.com/science-bspace.aspx?ssipg=BSShow%7csub=DisplayBlog&id=2559369a-9d54-4c20-a793-ed48378602a1&sid=74e9145a-7b90-45ca-b8d1-390ecd336650.

A tool for visualizing abnormal read pairs (i.e. too far apart, forward-forward or reverse-reverse). One of the ways to identify structural variation in a genome is to look at mapping of a read-pair library on a reference genome. Any read-pair (i.e. the ends of the same clone) normally maps in a forward-reverse orientation at a distance from each other that corresponds to the insert size of the clone library. Structural variation between the reference genome used for mapping and the genome used to create the clone library will cause the reads to map in the wrong orientation (i.e. forward-forward or reverse-reverse; indicating an inversion) or at too large or too small a distance (indicating an insertion or deletion in the sample, respectively). pARP basically displays raw read pair mapping data and does not make any assumptions on models as might be required when doing a statistical analysis of the same data. By showing a birds' eye view it helps in interpreting what structural variations are present.

nucleotide blast Search a nucleotide database using a nucleotide query Algorithms: blastn, megablast, discontiguous megablast protein blast Search protein database using a protein query Algorithms: blastp, psi-blast, phi-blast blastx Search protein database using a translated nucleotide query tblastn Search translated nucleotide database using a protein query tblastx Search translated nucleotide database using a translated nucleotide query