Journal of Neuropsychiatric Disease and Treatment - Dove Press - 0 views
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Increasing evidence has shown that, in animal stroke models, administering melatonin significantly reduces infarct volume, edema, and oxidative damage and improves electrophysiological and behavioral performance.
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Tero Toivanen on 16 Mar 09Melatonin also improves behavioral performance.
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Given that melatonin shows almost no toxicity to humans and possesses multifaceted protective capacity against cerebral ischemia, it is valuable to consider using melatonin in clinical trials on patients suffering from stroke.