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Tero Toivanen

Childhood Disintegrative Disorder, Autism/PDD: Yale Child Study Center - 0 views

www.med.yale.edu/...cdd.html

disintegrative autism_pdd

shared by Tero Toivanen on 27 Feb 09 - Cached
  • Childhood Disintegrative Disorder This rather rare condition was described many years before autism (Heller, 1908) but has only recently been 'officially' recognized.
  • The condition develops in children who have previously seemed perfectly normal. Typically language, interest in the social environment, and often toileting and self-care abilities are lost, and there may be a general loss of interest in the environment. The child usually comes to look very 'autistic', i.e., the clinical presentation (but not the history) is then typical of a child with autism.
  • A special educator in Vienna, Theodore Heller, proposed the term dementia infantilis to account for the condition.
  • ...3 more annotations...
  • in most cases after even very extensive testing no specific medical cause for the condition is found. As with autism, children who suffer from this condition are at increased risk for seizures.
  • evidence suggest that it arises as a result of some form of central nervous system pathology.
  • Childhood disintegrative disorder is perhaps 10 times less common than more strictly defined autism
  • Tero Toivanen on 27 Feb 09
     
    Childhood Disintegrative Disorder This rather rare condition was described many years before autism (Heller, 1908) but has only recently been 'officially' recognized.
Tero Toivanen

Childhood disintegrative disorder: Causes - MayoClinic.com - 0 views

www.mayoclinic.com/...DSECTION=causes

disintegrative mayoclinic

shared by Tero Toivanen on 27 Feb 09 - Cached
  • Causes There's no known cause of childhood disintegrative disorder, also known as Heller's syndrome. Most experts agree that there's likely a genetic basis for autism spectrum disorders. The theory is that an abnormal gene is switched on in the early stages of development, before birth, and that this gene affects other genes that coordinate a child's brain development.
  • Tero Toivanen on 27 Feb 09
     
    Causes There's no known cause of childhood disintegrative disorder, also known as Heller's syndrome. Most experts agree that there's likely a genetic basis for autism spectrum disorders. The theory is that an abnormal gene is switched on in the early stages of development, before birth, and that this gene affects other genes that coordinate a child's brain development.
Tero Toivanen

Childhood disintegrative disorder: Symptoms - MayoClinic.com - 0 views

www.mayoclinic.com/...DSECTION=symptoms

disintegrative mayoclinic

shared by Tero Toivanen on 27 Feb 09 - Cached
  • Tero Toivanen on 27 Feb 09
     
    Symptoms Children with childhood disintegrative disorder typically show the following signs and symptoms:
Tero Toivanen

Childhood disintegrative disorder - MayoClinic.com - 0 views

www.mayoclinic.com/...DS00801

disintegrative mayoclinic

shared by Tero Toivanen on 27 Feb 09 - Cached
  • Tero Toivanen on 27 Feb 09
     
    Definition Childhood disintegrative disorder is a condition in which children develop normally until age 3 or 4, but then demonstrate a severe loss of social, communication and other skills.
Tero Toivanen

Autism Blog - » Blog Archive » Is there an autism epidemic - the latest science - 0 views

leftbrainrightbrain.co.uk/?p=2023

autism epidemic Eric Fombonne autism-epidemic epidemiology omnibus experts science

shared by Tero Toivanen on 26 Mar 09 - Cached
  • A new paper from Eric Fombonne is in electronic print at the journal Pediatric Research.
  • The title is ‘Epidemiology of pervasive developmental disorders’
  • Combining all these categories together Fombonne presents a prevalence of 60-70/10,000.
  • ...10 more annotations...
  • Pervasive Developmental Disorders, including Autistic Disorder, Asperger Disorder, Pervasive Developmental Disorder Not Otherwise Specified, and Childhood Disintegrative Disorder.
  • For autistic disorder, Fombonne says: The correlation between prevalence and year of publication was statistically significant and studies with prevalenceover 7/10,000 were all published since 1987. These findings point towards an increase in prevalence estimates in the last 15-20 years.
  • recent autism surveys have consistently identified smaller numbers of children with AS than those with autism within the same survey.
  • We therefore used for subsequent calculations an estimate of 6/10,000 for AS, recognizing the strong limitations of available data on AS.
  • How much lower is difficult to establish from existing data, but a ratio of 3 or 4 to 1 would appear an acceptable,
  • Eight studies provided data on childhood disintegrative disorder (CDD). Prevalence estimates ranged from 0 to 9.2/100,000.
  • Current evidence does not strongly support the hypothesis of a secular increase in the incidence of autism but power todetect time trends is seriously limited in existing datasets.
  • The upper-bound limit of the associated confidence interval (4.0/100,000) indicates that CDD is a very rare condition, with about 1 case to occur for every 103 cases of autistic disorder.
  • Whilst it is clear that prevalence estimates have gone up over time, this increase most likely represents changes in the concepts, definitions, service availability and awareness of autistic-spectrum disorders in both the lay and professional public.
  • The possibility that a true change in the underlying incidence has contributed to higher prevalence figures remains, however, to be adequately tested.
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