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The relationship between music and neuroscience involved many research teams, one coming from the Rotman Research Institute in Canada. For this project, the team arranged a group of 19 volunteers, each given short song excerpts (all familiar with the style). While the participants listened, the brains, being scanned by MRI, highlighted one region: the nucleus accumbens, responsible for the sensation of pleasant surprise. However, this only works when the style is recognized.

Since the 1920s, researchers have recorded rhythmic patterns or electrical impulses in the brain. Now, rhythm is known to have effects on perception, attention, working memory, learning, and language. Gazzaley, a neuroscientist, wants to determine if these rhythms vary between healthy individuals. He is also interested in exploring what roles these rhythms play in various disorders. In one experiment, Gazzaley worked with the drummer, Mickey Hart, by strapping him to an EEG while playing the drums. Hart's brain was shown on screen, live.

Using a computer program, Neuroscientist Kamitani led an experiment to compare the brain's activity during sleep and during wake. This study involved 3 adult males, who were hooked up to a fMRI (used to measure brain activity). Being told to describe the things they saw in their dreams, the 3 adults were also asked to look at those objects in real life. Kamitani's study revealed that the brain responded similarly to objects dreamt about or seen awake.