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Nicholas Scholz

Multiple Sclerosis - 0 views

  • Multiple sclerosis (or MS) is a chronic, often disabling disease that attacks the central nervous system (CNS)
  • MS is a disease that involves an immune system attack against the central nervous system (brain, spinal cord, and optic nerves)
  • Although MS is thought by some scientists to be an autoimmine disease, others disagree strongly because the specific target of the immune attack in MS has not yet been identified. For this reason, MS is referred to as an immune-mediated disease.
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  • As part of the immune attack on the central nervous system, myelin (the fatty substance that surrounds and protects the nerve fibers in the central nervous system) is damaged, as well as the nerve fibers themselves
  • The damaged myelin forms scar tissue (sclerosis
  • Relapsing-Remitting MS
  • People with this type of MS experience clearly defined attacks of worsening neurologic function. These attacks—which are called relapses, flare-ups, or exacerbations —are followed by partial or complete recovery periods (remissions
  • Primary-Progressive MS
  • This disease course is characterized by slowly worsening neurologic function from the beginning—with no distinct relapses or remissions
  • Secondary-Progressive MS
  • Following an initial period of relapsing-remitting MS, many people develop a secondary-progressive disease course in which the disease worsens more steadily, with or without occasional flare-ups, minor recoveries (remissions), or plateaus
  • Progressive-Relapsing MS
  • In this relatively rare course of MS (5%), people experience steadily worsening disease from the beginning, but with clear attacks of worsening neurologic function along the way
  • but the disease continues to progress without remissions.
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    Multiple sclerosis has been associated with attacks against the central nervous system. The immune system has been identified to targeting organs such as the brain, spinal cord, and optic nerves. It is known as an immune - mediated disease because there is no specific target that has been identified. The attacks by the immune system often damage myelin and create scarred tissue (sclerosis). Patients with multiple sclerosis could experience one of four courses identified with the disease. One course is the Relapsing-Remitting MS. In this course the patient experiences a severe attack on the CNS followed by remissions. The second course is known as the Primary-Progressive MS. In this course the central nervous system slowly deteriorates without any relapses or remissions. Another course of MS is the Secondary-Progressive MS. This form of MS generally follows the relapsing-remitting form of MS and progressively worsens the CNS with or without remissions and plateaus. The most rare form of MS is perhaps the Progressive-Relapsing MS. In this course of MS, patients generally experience a progressive worsening of neurological function, without any remissions.  
Nicholas Scholz

How do Medical Professionals Diagnose Brain Tumors? - 0 views

  • The neurological exam includes checking vision, hearing, strength, sensation, balance, coordination, reflexes and ability to think and remember
  • An angiogram is a type of X-ray of the head that shows the brain’s arteries and veins
  • To show abnormalities like a brain tumor, a contrast dye is often used
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  • CT scans are a type of X-ray that creates a three-dimensional picture of the head by scanning the head from multiple different angles
  • CT scans can be helpful in diagnosing some types of brain tumors, especially those near or involving bone
  • DTIs measure the flow of water through the white matter tracts of the brain. This provides a snapshot of the brain's structure and can be used to compare changes over time.
  • This scan allows the surgeon and treating team to visualize the circuitry (or wiring) of the brain to guide the surgery
  • FMRI is used to determine the specific location of the brain where a certain function, such as speech or motor function, occurs
  • Patients can undergo functional MRIs (fMRI) to help delineate a roadmap of important structures (such as areas that control the arms, legs, or speech) prior to surgery
  • . These scans use magnetic fields and radio waves, rather than X-rays, and computers to create detailed pictures of the brain.
  • MRS is similar to MRI, except that it measures the function of the brain rather than its structure
  • A PET scan detects changes in cells as they grow
  • A biopsy is a surgical procedure to remove a small sample of the tumor for examination under a microscope
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    This article provides information regarding the diagnosis of brain tumors. The first step in diagnosing brain tumors is a neurological exam. This type of exam is used to check vision, hearing, strength, sensation, and other cognitive skills. If deemed necessary other exams can be performed to determine characteristics of the tumors. The first is an angiogram, which is a type of x-ray for the head which examines arteries and veins. The second type is a brain scan, which shows abnormalities using a contrast dye. Another type of scan is the CT scan which creates a 3 dimensional image of the brain which can be useful in diagnosing brain tumors especially near bones. Diffusion Tensor Imaging (DTI) is a type of scan which measures the flow of water through white matter of the brain. This method provides a snapshot of brains structure and can be very useful during surgical procedures allowing physicians a guide to the rest of the brain. An fMRI is used to determine specific locations related to specific functions. This type of diagnostic tool helps create a guide to specific functions of the brain which is used to better prepare for surgery. The common MRI uses a magnetic field and radio waves to create pictures of the brain. A similar MRS measures the function of the brain rather than its structure. Additionally, PET scans detect changes in the cells using an injection of radioactive glucose. Finally, the most effective way to diagnose a patient is by using a biopsy. A biopsy is a surgical procedure which a profile of tissue is collected and examined under a microscope. Most biopsy's are done using surgery, although there are a couple of different types of needle biopsy's.
Nicholas Scholz

Alzheimer's - Alzheimer's Association - 0 views

  • Alzheimer's is a type of dementia that causes problems with memory, thinking and behavior.
  • Alzheimer's disease accounts for 50 to 80 percent of dementia cases.
  • Up to 5 percent of people with the disease have early onset Alzheimer's
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  • Those with Alzheimer's live an average of eight years after their symptoms become noticeable
  • However, serious memory loss, confusion and other major changes in the way our minds work may be a sign that brain cells are failing.
  • Each nerve cell connects with many others to form communication networks
  • Keeping everything running requires coordination as well as large amounts of fuel and oxygen
  • Plaques are deposits of a protein fragment called beta-amyloid (BAY-tuh AM-uh-loyd) that build up in the spaces between nerve cells.
  • Tangles are twisted fibers of another protein called tau (rhymes with “wow”) that build up inside cells.
  • It's the destruction and death of nerve cells that causes memory failure, personality changes, problems carrying out daily activities and other symptoms of Alzheimer'
  • Ninety percent of what we know about Alzheimer's has been discovered in the last 15 years
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    Alzheimer's is actually a common form of dementia. Roughly 50-80 percent of patients with dementia are associated with Alzheimer's. Alzheimer's is considered a neurological disorder with loss of memory, thinking and behavioral function. Alzheimer's is common diagnosed in patients 65 and older with the exception of patients with Early-Onset Alzheimer's. Alzheimer's progressively worsens over time and commonly culminates in death 8 years after symptoms start to arrive. Again no cure has been found for alzheimer's, but certain medications are used to treat symptoms. A build-up of plaques and tangles in the brain is suspected to kill nerve cells and cause a loss of brain function. The loss of nerve cells causes gaps in the communication network and eventually causes a loss of function in those areas of the brain. Although scientists do not know their exact role in Alzheimer's, patients have been associated with an abundant amount of these abnormal structures.
Nicholas Scholz

Epilepsy - NIH - 0 views

  • The epilepsies are a spectrum of brain disorders ranging from severe, life-threatening and disabling, to ones that are much more benign
  • seizures can be controlled with modern medicines and surgical techniques
  • Epilepsy may develop because of an abnormality in brain wiring, an imbalance of nerve signaling chemicals called neurotransmitters
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  • Only when a person has had two or more seizures is he or she considered to have epilepsy
  • For about 70 percent of those diagnosed with epilepsy,
  • normal pattern of neuronal activity becomes disturbed, causing strange sensations, emotions, and behavior
  • Issues may also arise as a result of the stigma attached to having epilepsy
  • the risk of seizures restricts their independence (some states refuse drivers licenses to people with epilepsy) and recreational activities.
  • Ongoing research is focused on developing new model systems that can be used to more quickly screen potential new treatments
  • Researchers funded by the National Institutes of Health have developed a flexible brain implant that could one day be used to treat seizures
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    Epilepsy is a neurological disorder associated with sudden seizures. In diagnosing epilepsy, the patient must have displayed two unexpected seizures. Epilepsy can be life - threatening and disabling or benign. Typical symptoms associated with epilepsy are strange sensations, emotions, and behavior. The cause of epilepsy is uncertain, but abnormal brain wiring may have an effect. With no cure for epilepsy, modern day medications and surgeries are used to treat patients. Due to the stigma associated with epilepsy, some children develop behavioral and emotional issues. The restriction of independence, like being denied a drivers license due to seizures, is also emotionally challenging for these patients. Current research being conducted for patients with epilepsy include the development of new models used to determine treatments, and brain implants which control seizures. 
Nicholas Scholz

Parkinsons DIsease - NIH - 0 views

  • Parkinson's disease (PD) belongs to a group of conditions called motor system disorders, which are the result of the loss of dopamine-producing brain cells
  • symptoms of PD are tremor, or trembling in hands
  • bradykinesia, or slowness of movemen
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  • As these symptoms become more pronounced, patients may have difficulty walking, talking, or completing other simple tasks
  • difficulty in swallowing
  • At present, there is no cure for PD
  • and progressive
  • A therapy called deep brain stimulation (DBS) has now been approved by the U.S. Food and Drug Administration
  • Usually, patients are given levodopa
  • movements called dyskinesias that are a common side effect of levodopa
  • PD is both chronic
  • In some cases, surgery may be appropriate if the disease doesn't respond to drugs
  • No one can predict which symptoms will affect an individual patient, and the intensity of the symptoms also varies from person to person.
  • PD research in laboratories at the National Institutes of Health (NIH)
  • Scientists looking for the cause of PD
  • develop new protective drugs that can delay, prevent, or reverse the disease.
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    This article pertains to the neurological disorder, Parkinson's Disease (PD). PD is known to reduce motor system function due to the loss of dopamine-producing brain cells. Most symptoms related to PD include tremors, trembling, and slowness of movement (bradykinesia). As the disease progresses these tremors begin to effect daily activities like chewing and speaking. Unfortunately there is no cure for Parkinson's Disease. The most common treatment for PD is the use of medications such as levodopa. Due to complications with current medications other treatments like deep brain stimulation and surgery are commonly used. Parkinson's Disease is both chronic and progressive. Tremors and other symptoms will occur for long periods of time and possibly grow worse. Patients with PD experience varying symptoms and intensities. Current research being done in response to Parkinson's is being conducted at the National Institute of Health (NIH) and elsewhere. Current topics of research include discovering the cause of PD, and the development of protective drugs needed to delay, prevent, and even reverse the disease.
Nicholas Scholz

Severe Complications Related to Cancerous Brain Tissue - 0 views

  • About two-thirds of patients with brain metastases will have symptoms that can range from headache to vision problems to confusion
  • These metastases can lead to spinal cord compression, which in the most severe cases can cause permanent paralysis and/or incontinenc
  • Plexopathies cause pain and occur when cancer spreads to the plexus, a network of interweaving nerves, blood
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  • essels, or lymph vessel
  • h vessel
  • Cancer can also spread to the tissues that cover the brain and spinal cord, called the leptomeningeal tissues
  • There is a strong correlation between deep vein thrombosis and cancer: patients who present with deep vein thrombosis are more likely to be diagnosed with cancer
  • Paraneoplastic disorders are a group of conditions related only because they result from biological side effects of cancer
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    This essay explains the types of complications related to neurological conditions and how they effect the body. The first complication is of course related to the origination of brain tumors themselves. Brain metastases is caused by the spread of cancerous cells to brain from other areas of the body. Symptoms could include that of headaches to vision problems. The next topic of discussion is the Epidural Spinal Cord Compression. This is another type of metastases which can lead to spinal cord compression and possible paralysis. Common issues associated with this type of metastases include breast, prostate, or lung cancer. Additionally, Plexopathies are caused by the spread of cancer to the plexus. This type of complication causes serious pain and has the ability to migrate towards other areas of the plexus. Leptomeningeal Metastases is caused by the spread of cells to the tissues which cover the brain and spinal cord and could effect cognitive skills. Another complication is a vascular disorder. Vascular disorders and cancer are believed to correlate with a deep vein thrombosis. Finally, paraneoplastic disorder is a complication that is caused by a group of conditions which create biological side effects. These side effects include release of substances into the blood stream and inappropriate immune system responses.
Priya S.K.

Music Therapy for Health and Wellness | Psychology Today - 0 views

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    As a pharmacist, Catherine Ulbricht studied different types of music and its therapeutic effects. There are scientific evidences that support that music influences mood and helps with stress. 5 conditions for which music therapy has good evidence for are autism, dementia, depression, infant development, and sleep quality. However, music shouldn't be listened to at high volumes nor should be a sole treatment for dangerous medical/psychiatric conditions; therefore, safety should be taken into account.
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