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Ellen L

Access : Social isolation delays the positive effects of running on adult neurogenesis ... - 0 views

  • Social isolation can exacerbate the negative consequences of stress and increase the risk of developing psychopathology.
  • individual housing precludes the positive influence of short-term running on adult neurogenesis in the hippocampus of rats and, in the presence of additional stress, suppresses the generation of new neurons.
  • These results suggest that, in the absence of social interaction, a normally beneficial experience can exert a potentially deleterious influence on the brain.
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    Studies have shown that a lack of social interaction turns usually beneficial activities, such as running, into detrimental ones, as a lack of interaction causes elevated levels of corticosterone to be produced, suppressing the generation of new neurons. This reflects the fine line Victor walked between sanity and insanity, as the isolation has a tendency to produce psychopathic effects. 
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