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A US drug company has agreed to pay out $1.6bn (£1bn) after improperly marketing a mood-stabilising drug in a settlement thought to be the largest of its kind involving a single drug. Abbott Laboratories encouraged its sales teams to market Depakote for uses that were not approved by regulators, the US justice department said.

Trading blocs A regional trading bloc is a group of countries within a geographical region that protect themselves from imports from non-members. Trading blocs are a form of economic integration, and increasingly shape the pattern of world trade.