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Whooping cough (say: hoop-ing kof) - also called pertussis (say: pur-tuh-sus) - is one of those illnesses. It's a bacterial infection of the respiratory system, which includes your lungs and breathing tubes. Whooping cough got its name because kids who had it would cough a lot, and in between coughs, they'd make a "whoop" sound when they tried to get a breath.