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Mesenchymal stem cells are a subset of pluripotent stem cells which can be isolated from the mesoderm. With their self-replication renewal and multi-direction differentiation characteristics, they possess a high potential for various therapies in medicine. Mesenchymal stem cells have a unique immune phenotype and immune regulation ability. Therefore, mesenchymal stem cells are already widely used in stem cell transplantations, tissue engineering and organ transplantation. And Beyond these applications, they are used as an ideal tool in tissue engineering as seeder cells in a series of basic and clinical research experiments.