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Urease inhibitors are a class of chemical agents that inhibit urease activity in soil and delay urea hydrolysis. Soil urease is a specific hydrolase that catalyzes the hydrolysis of urea in the soil.

Urease inhibitor is a kind of substance that can inhibit the activity of soil urease, and it is a new technology which has been studied in urea or nitrogen compound fertilizer. Using soil urease inhibitor can effectively slow decomposition of urea into ammonia process, reduce soil NH4 + and NH3 concentration, soil fertility and crop fertilizer synchronization.